scholarly journals Coadministration of Curcumin and Hydromorphone Hydrochloride Alleviates Postoperative Pain in Rats

2022 ◽  
Vol 45 (1) ◽  
pp. 27-33
Author(s):  
Yihan Wang ◽  
Yang Liu ◽  
Jieting Liu ◽  
Min Wang ◽  
Yingbin Wang
Keyword(s):  
1999 ◽  
Vol 56 (8) ◽  
pp. 460-464 ◽  
Author(s):  
Janson ◽  
Brunne
Keyword(s):  

Eine adäquate Therapie postoperativ auftretender Schmerzen verbessert nicht nur das Wohlbefinden der Patienten, sondern beeinflußt auch die posttraumatische bzw. postoperative Pathophysiologie positiv. Dazu stehen neben der kontinuierlichen bzw. repetitiven Applikation von Antipyretika und Opioiden auch spezielle Methoden wie die intravenöse Patienten-kontrollierte Analgesie (PCA) und die Epiduralanalgesie zur Verfügung. Während bisher allein die Verbesserung der Analgesiequalität im Vordergrund der Bemühungen stand, werden zur Zeit neue Konzepte mit einem multimodalen Ansatz entwickelt. Dabei soll mit Hilfe der Analgesie eine gute Mobilisierbarkeit, ein früher enteraler Kostaufbau und eine insgesamt schnellere Konsolidierung des Patienten mit dem Ziel der Reduktion perioperativer Morbidität und Mortalität erreicht werden.


2016 ◽  
Vol 64 (S 01) ◽  
Author(s):  
F. Dörr ◽  
S. Macherey ◽  
M. Heldwein ◽  
S. Stange ◽  
T. Wahlers ◽  
...  

Author(s):  
Daniel J. Lynch ◽  
James S. Lin ◽  
Kanu S. Goyal

Abstract Introduction This study looked to determine how providing written prescriptions of nonopioids affected postoperative pain medication usage and pain control. Materials and Methods Patients undergoing hand and upper-extremity surgery (n = 244) were recruited after the implementation of a postoperative pain control program encouraging nonopioids before opioids. Patients were grouped based on procedure type: bone (n = 66) or soft tissue (n = 178). Patients reported postoperative medication consumption and pain control scores. Two-tailed t-tests assuming unequal variance were performed to look for differences in postoperative pain control and medication consumption between those who were and were not given written prescriptions for nonopioids. Results For both soft tissue and bone procedure patients, a written prescription did not significantly affect patients’ postoperative pain control or medication consumption. Regardless of receiving a written prescription, patients who underwent soft tissue procedures consumed significantly more daily nonopioids than opioids. Conclusion Receiving written prescriptions for nonopioids may not have a significant effect on postoperative pain control or medication consumption. Patients undergoing soft tissue hand and upper extremity procedures may be more likely to consume more daily nonopioids than opioids postoperatively compared to bone procedure patients regardless of whether they receive a written prescription for nonopioids.


Author(s):  
Rubina Yasmin ◽  
AKM Akhtaruzzaman ◽  
Paresh Chandra Sarker ◽  
Neaz Ahmed ◽  
Ranadhir Kumar Kundu ◽  
...  

This prospective clinical study was carried out in the Dept. of Anaesthesia, Analgesia and Intensive Care Medicine, BSMMU, Dhaka, during the period of May 2003 to July 2003. The study was done to emphasize the importance of giving analgesics preemptively instead of waiting for the child to complain of pain and to produce smooth recovery after surgery by decreasing immediate postoperative pain in children by a simple, safe acceptable drug. The children scheduled for tonsillectomy under general anaesthesia were recruited in this study. The analgesic efficiency of rectal paracetamol in two doses, 25 mg/kg bodywt.(Gr-P25) and 50 mg/kg. bodywt. (Gr-P50) were compared with Diclofenac Sodium suppository 1mg/ kg body weight (Gr-D) given half an hour before induction of anaesthesia. Pain scoring was done by TPPPS (Toddler Pre-schooler postoperative pain scale). Heart rate and blood pressure were stable in Gr-P50 and Gr-D. Time of first demand of analgesic was delayed in Gr-P50 and Gr-D. Total paracetamol consumption in 24 hours was less in Gr-P50(181±14.25) and Gr-D (212±25) than Gr-P25(318± 26.39). Total duration of analgesia in Gr- P50 (657±9.94) mins. and in Gr- D(502±10.63) mins. and in Gr-P25(288±23.17) mins. Pre-emptive high dose rectal paracetamol appears to be more effective than diclofenac sodium suppository for postoperative analgesia in children undergoing tonsillectomy. Journal of BSA, Vol. 18, No. 1 & 2, 2005 p.9-16


Sign in / Sign up

Export Citation Format

Share Document