A new method of quantification of the pulmonary regional distribution of aerosols using combined CT and SPECT and its application to nedocromil sodium administered by metered dose inhaler

1994 ◽  
Vol 67 (793) ◽  
pp. 46-53 ◽  
Author(s):  
S Perring ◽  
Q Summers ◽  
J S Fleming ◽  
M A Nassim ◽  
S T Holgate
1994 ◽  
Vol 3 (7) ◽  
pp. S35-S37 ◽  
Author(s):  
F. M. de Benedictis ◽  
G. Tuteri ◽  
A. Niccoli ◽  
D. Mezzetti ◽  
L. Rossi ◽  
...  

To compare the effectiveness of cromolyn sodium (CS) (10 mg) and nedocromil sodium (NS) (4 mg) administered by a metered dose inhaler (MDI) with a spacer device in preventing exercise-induced asthma (EIA), eight asthmatic children with EIA were studied in a randomized double-blind, cross-over, placebo-controlled study, CS and NS provided significant, comparable protection from EIA and both were better than placebo. We conclude that CS and NS administered by a pressurized aerosol with a spacer device provide equal protection against EIA in children.


Respiration ◽  
1988 ◽  
Vol 53 (2) ◽  
pp. 65-73 ◽  
Author(s):  
Dieter Köhler ◽  
Wolfgang Fleischer ◽  
Heinrich Matthys

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