scholarly journals A feasibility study of hyoscine butylbromide (buscopan) to improve image quality of cone beam computed tomography during abdominal/pelvic Stereotactic Ablative Radiotherapy

BJR|Open ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 20210045
Author(s):  
Finbar Slevin ◽  
Matthew Beasley ◽  
Jim Zhong ◽  
Eleanor Hudson ◽  
Richard Speight ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Cone Beam Computed Tomography ◽  
Feasibility Trial ◽  
Cone Beam ◽  
Stereotactic Ablative Radiotherapy ◽  
Motion Artefact ◽  
Hyoscine Butylbromide ◽  
Bowel Motion ◽  
The Impact

Objectives: Cone beam computed tomography (CBCT) is used for image guidance of stereotactic ablative radiotherapy (SABR), but it is susceptible to bowel motion artefacts. This trial evaluated the impact of hyoscine butylbromide (buscopan) on CBCT image quality and its feasibility within a radiotherapy workflow. Methods: A single-centre feasibility trial (ISRCTN24362767) was performed in patients treated with SABR for abdominal/pelvic oligorecurrence. Buscopan was administered to separate cohorts by intramuscular (IM) or intravenous (i.v.) injection on alternate fractions, providing within-patient control data. 4-point Likert scales were used to assess overall image quality (ranging from excellent to impossible to use) and bowel motion artefact (ranging from none to severe). Feasibility was determined by patient/radiographer questionnaires and toxicity assessment. Descriptive statistics are presented. Results: 16 patients were treated (8 by IM and 8 by i.v. buscopan). The percentage of images of excellent quality with/without buscopan was 47 vs 29% for IM buscopan and 65 vs 40% for i.v. buscopan. The percentage of images with no bowel motion artefact with/without buscopan was 24.6 vs 8.9% for IM buscopan and 25.8 vs 7% for i.v. buscopan. Four patients (25%) reported dry mouth. 14 patients (93%) would accept buscopan as routine. 11 radiographers (92%) reported no delay in treatments. Conclusions: A trend towards improved image quality/reduced bowel motion artefact was observed with IM/i.v. buscopan. Buscopan was well tolerated with limited impact on workflow. Advances in knowledge: This is the first trial of buscopan within a radiotherapy workflow. It demonstrated a trend to improved image quality and feasibility of use.

scholarly journals A technical note on intra-arterial cone-beam computed tomography for the evaluation of flow-diverter stents: Image quality differences between diluted and non-diluted contrast medium

2019 ◽  
Vol 26 (2) ◽  
pp. 164-169
Author(s):  
Naci Kocer ◽  
Sedat G Kandemirli ◽  
Daniel Ruijters ◽  
Michalis Mantatzis ◽  
Osman Kizilkilic ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Contrast Medium ◽  
Cone Beam Computed Tomography ◽  
Vessel Wall ◽  
Flow Diverter ◽  
Cone Beam ◽  
Gray Scale ◽  
Stent Deployment ◽  
Contrast Technique

Background Design of flow-diverter stents for flexibility, tractability, and low profile limits their radiopacity on conventional digital subtraction angiography. Cone-beam computed tomography (CBCT) offers higher spatial resolution for the evaluation of flow-diverter stents. However, CBCT requires optimal dilution and timing of contrast medium for simultaneous visualization of the stent, arterial lumen, and vessel wall. There are only limited data on the effects of different contrast dilutions on CBCT image quality in neurointerventional applications. Materials and methods In our institution, intra-arterial CBCTs were acquired during stent deployment and at follow-ups with 10% diluted contrast. We had recently started acquiring intra-arterial CBCTs with non-diluted contrast. Retrospective analysis of our flow-diverter data identified eight cases with different aneurysm locations who had intra-arterial CBCT with 10% diluted contrast immediately after flow-diverter stent deployment and with non-diluted contrast technique during follow-ups. For each case, the image quality between diluted and non-diluted contrast techniques was compared qualitatively by assessing stent visualization and quantitatively by plotting gray-scale intensity values along the vessel lumen. Results In two sets of CBCT images per each case, there was no substantial difference between diluted and non-diluted CBTC techniques for the evaluation of stent architecture and lumen opacification. Gray-scale intensity values perpendicular to the lumen revealed similar intensity values along the neighboring parenchyma, vessel wall, and lumen for the two different contrast techniques. Conclusion Intra-arterial CBCT angiography can be performed without contrast dilution and still achieve adequate image quality in certain cerebral aneurysms treated with flow diverter. The non-diluted contrast technique avoids the time loss during preparation of diluted contrast and installation of diluted contrast to the injector in angiography suites with a single power injector.

Feasibility study of a s ynchronized-mo ving-g rid (SMOG) system to improve image quality in cone-beam computed tomography (CBCT)

2012 ◽  
Vol 39 (8) ◽  
pp. 5099-5110 ◽  
Author(s):  
Lei Ren ◽  
Fang-Fang Yin ◽  
Indrin J. Chetty ◽  
David A. Jaffray ◽  
Jian-Yue Jin
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Feasibility Study ◽  
Cone Beam Computed Tomography ◽  
Cone Beam ◽  
Improve Image Quality

Influence of cone-beam computed tomography milliamperage settings on image quality of the mandibular third molar region

2013 ◽  
Vol 30 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Frederico Sampaio Neves ◽  
Thaís de Camargo Souza ◽  
Sérgio Lins de-Azevedo-Vaz ◽  
Paulo Sérgio Flores Campos ◽  
Frab Norberto Bóscolo
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Cone Beam Computed Tomography ◽  
Third Molar ◽  
Cone Beam ◽  
Mandibular Third Molar ◽  
Molar Region

Patient dose and image quality from mega-voltage cone beam computed tomography imaging

2007 ◽  
Vol 34 (2) ◽  
pp. 499-506 ◽  
Author(s):  
Olivier Gayou ◽  
David S. Parda ◽  
Mark Johnson ◽  
Moyed Miften
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Cone Beam Computed Tomography ◽  
Patient Dose ◽  
Cone Beam ◽  
Computed Tomography Imaging ◽  
Tomography Imaging

Assessment of image quality in maxillofacial cone-beam computed tomography imaging

2015 ◽  
Vol 21 (4) ◽  
pp. 248-253 ◽  
Author(s):  
Casey Gamache ◽  
Jeryl D. English ◽  
Anna M. Salas-Lopez ◽  
John Rong ◽  
Sercan Akyalcin
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Cone Beam Computed Tomography ◽  
Cone Beam ◽  
Computed Tomography Imaging ◽  
Tomography Imaging

Fast acquisition cone-beam computed tomography: initial experience with a 10 s protocol

2018 ◽  
Vol 10 (9) ◽  
pp. 916-920 ◽  
Author(s):  
Visish M Srinivasan ◽  
Gouthami Chintalapani ◽  
Kevin Matthew Camstra ◽  
Sabih T Effendi ◽  
Jacob Cherian ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Cone Beam Computed Tomography ◽  
Cone Beam ◽  
Head Model ◽  
Parent Artery ◽  
Swine Model ◽  
Cerebrovascular Lesions ◽  
Acquisition Protocol ◽  
Scan Time

BackgroundCone-beam computed tomography (CBCT) facilitates the acquisition of cross-sectional imaging in angiography suites using a rotational C-arm and digital flat panel detectors. The applications are numerous, including evaluation of implanted devices and localization of cerebrovascular lesions. We present and validate the clinical utility of an alternative fast CBCT acquisition protocol in the context of neurovascular device imaging.MethodsContrast-enhanced (CE)-CBCT images were acquired using a new 10 s protocol in a phantom head model, swine model, and in patients. The acquisition parameters of both the 10 s and 20 s protocols were exactly the same, except for fewer projections (250 projections in 10 s vs 500 projections in 20 s), resulting in reduced scan time. Image quality was measured quantitatively in a controlled phantom study and qualitatively by blinded reviewers. The latter was performed to assess the image quality of the 10 s protocol pertinent to the device visibility and its apposition to the parent artery.Results10 s CBCT images were comparable to 20 s CBCT in both phantom and animal studies. Of the 25 patient images, the reviewers agreed that they were able to discern the flow diverter struts and assess the apposition in all images. The overall rating for all 10 s images was 4.28 on a 5-point scale. No images were rated as less than 3, which was the average diagnostic quality. The ratings were concordant across three blinded reviewers (κ=0.411). Additionally, contrast and spatial resolution between 10 s and 20 s images were similar in non-human models.ConclusionsCBCT images of neurovascular devices can be obtained successfully using a 10 s acquisition protocol. In addition, the 10 s protocol offers faster acquisition, thus allowing its use in awake patients and with an added advantage of lower radiation and contrast dose.

Sign in / Sign up

Export Citation Format

Share Document