Serum serotonin concentration in small breed dogs with degenerative mitral valve disease

2015 ◽  
Vol 16 (4) ◽  
pp. 177-181
Author(s):  
Soo-Jung Lim ◽  
Sun-Hee Lee ◽  
Kun-Ho Song
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Serotonin Concentration ◽  
Serum Serotonin ◽  
Small Breed

scholarly journals Serum serotonin concentration in lean and obese dogs with myxomatous mitral valve disease

2016 ◽  
Vol 56 (4) ◽  
pp. 205-208
Author(s):  
Kyu-Tae Kim ◽  
Hee-Myung Park ◽  
Changbaig Hyun ◽  
Kyoung-Won Seo ◽  
Kun-Ho Song
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Serotonin Concentration ◽  
Serum Serotonin

Serum Serotonin Concentration Is Associated with Severity of Myxomatous Mitral Valve Disease in Dogs

2013 ◽  
Vol 27 (5) ◽  
pp. 1105-1112 ◽  
Author(s):  
I. Ljungvall ◽  
K. Höglund ◽  
I. Lilliehöök ◽  
M.A. Oyama ◽  
A. Tidholm ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Serotonin Concentration ◽  
Serum Serotonin

scholarly journals Assessment of Platelet and Plasma Serotonin in Canine Pulmonary Hypertension Secondary to Degenerative Mitral Valve Disease

2021 ◽  
Vol 8 ◽  
Author(s):  
Nattawan Tangmahakul ◽  
Pussadee Makoom ◽  
Sirilak Disatian Surachetpong
Keyword(s):  
Pulmonary Hypertension ◽  
Mitral Valve ◽  
Mitral Valve Disease ◽  
High Probability ◽  
Valve Disease ◽  
Serotonin Concentration ◽  
Platelet Serotonin ◽  
The Difference ◽  
Post Hoc ◽  
Plasma Serotonin

Background: Pulmonary hypertension (PH) is a common complication of degenerative mitral valve disease (DMVD), the most common cardiovascular disease in dogs. Serotonin has been suspected to play a role in the pathogenesis of PH, so this study aimed to investigate the differences in platelet and plasma serotonin between normal, DMVD and DMVD with PH (DMVD+PH) dogs.Materials and Methods: Sixty-two small-breed dogs were enrolled to the study and divided into the normal (n = 22), DMVD (n = 20), and DMVD+PH (n = 20) groups. The platelet and plasma serotonin concentrations were measured by the competitive ELISA.Results: The Kruskal–Wallis revealed the difference among the four groups of normal (179.73 [102.37–352.24] ng/109 platelets), DMVD (325.99 [96.84–407.66] ng/109 platelets), DMVD with intermediate probability of PH (291.11 [106.69–400.84] ng/109 platelets) and DMVD with high probability of PH (35.82 [2.69–126.35] ng/109 platelets) (p = 0.014). The Dunn's post-hoc test showed a decrease in the platelet serotonin concentration of the DMVD dogs with high probability of PH compared to the DMVD group (p = 0.008). The plasma serotonin concentration was not different between normal, DMVD, and DMVD+PH dogs.Conclusion: In conclusion, a decrease in platelet serotonin concentration, which is associated with a degree of PH probability was found in DMVD dogs with PH. Further studies investigating roles of platelet serotonin in PH secondary to DMVD should be performed.

scholarly journals Retrospective study of degenerative mitral valve disease in small-breed dogs: survival and prognostic variables

2017 ◽  
Vol 18 (3) ◽  
pp. 369 ◽  
Author(s):  
Hyun-Tae Kim ◽  
Sei-Myoung Han ◽  
Woo-Jin Song ◽  
Boeun Kim ◽  
Mincheol Choi ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Prognostic Variables ◽  
Small Breed

scholarly journals Holter Monitoring of Small Breed Dogs with Advanced Myxomatous Mitral Valve Disease with and without a History of Syncope

2014 ◽  
Vol 28 (2) ◽  
pp. 363-370 ◽  
Author(s):  
C.E. Rasmussen ◽  
T. Falk ◽  
A. Domanjko Petrič ◽  
M. Schaldemose ◽  
N.E. Zois ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Holter Monitoring ◽  
Valve Disease ◽  
History Of ◽  
Small Breed

Murmur intensity in small-breed dogs with myxomatous mitral valve disease reflects disease severity

2014 ◽  
Vol 55 (11) ◽  
pp. 545-550 ◽  
Author(s):  
I. Ljungvall ◽  
M. Rishniw ◽  
F. Porciello ◽  
L. Ferasin ◽  
D. G. Ohad
Keyword(s):  
Mitral Valve ◽  
Disease Severity ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Small Breed

scholarly journals Serum Serotonin Concentrations in Dogs with Degenerative Mitral Valve Disease

2009 ◽  
Vol 23 (6) ◽  
pp. 1208-1213 ◽  
Author(s):  
J.W. Arndt ◽  
C.A. Reynolds ◽  
G.E. Singletary ◽  
J.M. Connolly ◽  
R.J. Levy ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Serum Serotonin

Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

2015 ◽  
Vol 76 (6) ◽  
pp. 520-531 ◽  
Author(s):  
Signe E. Cremer ◽  
Annemarie T. Kristensen ◽  
Maria J. Reimann ◽  
Nynne B. Eriksen ◽  
Stine F. Petersen ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Platelet Serotonin ◽  
Serum Serotonin
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