scholarly journals Translating the 2020 AAD-NPF Guidelines of Care for the Management of Psoriasis With Systemic Nonbiologics to Clinical Practice

2021 ◽  
Vol 107 (2) ◽  
Author(s):  
Vipawee S Chat ◽  
Shelley K Uppal ◽  
Donovan G Kearns ◽  
George Han ◽  
Jashin J. Wu

In 2020, the American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) released a set of guidelines for the management of psoriasis in adults with systemic nonbiologic therapies, including acitretin, apremilast, cyclosporine, fumaric acid esters, methotrexate, and tofacitinib. This review addresses dosing, efficacy, toxicity, drug-related interactions, and contraindications alongside evidence-based treatment recommendations for each systemic therapy. Important considerations for treatment such as drug selection, initiation of therapy, drug monitoring, and patient management also are discussed. Physicians are encouraged to use these recommendations to guide treatments based on individual patient needs and disease characteristics.

2021 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
Shaheela Backar

Frontal fibrosing alopecia (FFA) is a primary progressive cicatricial alopecia of the frontal, temporal, or frontotemporal scalp. In FFA, hairline recession, scalp pruritus, perifollicular erythema, and eyebrow loss are common at presentation. At present, there are no evidence-based treatment guidelines for FFA; hence, adopted modalities of treatment vary among clinicians. This review is an overview of the disease characteristics and the available therapeutic options in FFA.


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