scholarly journals An H9N2 Influenza Virus Vaccine Prepared from a Non-Pathogenic Isolate from a Migratory Duck Confers Protective Immunity in Mice against Challenge with an H9N2 Virus Isolated from a Girl in Hong Kong

2012 ◽  
Vol 74 (4) ◽  
pp. 441-447 ◽  
Author(s):  
Naoki NOMURA ◽  
Yoshihiro SAKODA ◽  
Kosuke SODA ◽  
Masatoshi OKAMATSU ◽  
Hiroshi KIDA
2018 ◽  
Vol 153 ◽  
pp. 78-84 ◽  
Author(s):  
Hongjing Gu ◽  
Yaqian Gao ◽  
Shanshan Zhou ◽  
Fang Sun ◽  
Zhongpeng Zhao ◽  
...  

1974 ◽  
Vol 72 (1) ◽  
pp. 91-100 ◽  
Author(s):  
C. McLaren ◽  
C. W. Potter

SUMMARYNormal ferrets did not produce serum antibody following immunization with 200 i.u. of inactivated A/Hong Kong/68 influenza virus vaccine and were found to be susceptible to subsequent challenge infection with A/Hong Kong/68 virus. High titres of virus were recovered from nasal washings collected 3 days after infection, serum antibody was produced, increased nasal protein was detected and HI antibody was detected in nasal washings. Ferrets infected with influenza virus A/PR/8/34 7 weeks before immunization with inactivated A/HK/68 virus did, however, produce serum HI antibody to A/HK/68 virus. This antibody conferred partial immunity to challenge infection with A/HK/68 virus, as shown by decreased titres of virus in nasal washings and reduced levels of nasal protein. Previous infection of ferrets with influenza virus B/Ann Arbor/66 did not result in the production of serum antibody to A/HK/68 virus following immunization with A/HK/68 vaccine and the animals were completely susceptible to subsequent challenge infection with A/HK/68 virus. Differences in the amount of nasal protein and nasal antibody produced after A/HK/68 infection were also found in ferrets previously infected with either A/PR/8/34 or B/AA/66 virus, compared with normal ferrets.


1978 ◽  
Vol 81 (3) ◽  
pp. 331-336 ◽  
Author(s):  
Brian J. Feery ◽  
M. G. Evered ◽  
Kathleen Hayes

SummaryIn a group of 32 adult volunteers given subunit influenza virus vaccine containing 250 international units (i.u.) of A/Victoria/3/75, 250 i.u. of A/Scotland/ 840/74 and 300 i.u. of B/Hong Kong/8/73, there were substantial increases in the geometric mean homologous haemagglutination-inhibiting (HI) antibody titres. There was also substantial boosting of the antibodies to the earlier variants of the Hong Kong (H3N2) series and to a later variant of the Asian (H2N2) series. There was no boosting of antibodies to the A/FM/1/47 strain, a representative member of the H1N1 series, but two individuals showed substantial rises to A/PR/8/34 (H0N1).There were increases in the HI titre of antibodies cross reactive with two recent isolations, A/Texas/1/77, and A/Victoria/35/77, but the majority of vaccinees failed to reach antibody titres likely to be protective against such strains.


PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e98685 ◽  
Author(s):  
Rafael Polidoro Alves Barbosa ◽  
Ana Paula Carneiro Salgado ◽  
Cristiana Couto Garcia ◽  
Bruno Galvão Filho ◽  
Ana Paula de Faria Gonçalves ◽  
...  

2020 ◽  
Author(s):  
Nadiyah Alqazlan ◽  
Jake Astill ◽  
Khaled Taha-Abdelaziz ◽  
Éva Nagy ◽  
Byram Bridle ◽  
...  

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