scholarly journals Virucidal activity of a quaternary ammonium compound associated with calcium hydroxide on avian influenza virus, Newcastle disease virus and infectious bursal disease virus

2018 ◽  
Vol 80 (4) ◽  
pp. 574-577 ◽  
Author(s):  
Mariko ITO ◽  
Md. Shahin ALAM ◽  
Mayuko SUZUKI ◽  
Satoru TAKAHASHI ◽  
Miyuki KOMURA ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Infectious Bursal Disease Virus ◽  
Quaternary Ammonium Compound ◽  
Infectious Bursal Disease ◽  
Ammonium Compound ◽  
Virucidal Activity ◽  
Bursal Disease

Infectious Bursal Disease Virus: Molecular Epidemiologic Perspectives and Impact on Vaccine Efficacy Against Avian Influenza and Newcastle Disease Viruses

2019 ◽  
Vol 63 (4) ◽  
pp. 606 ◽  
Author(s):  
Tamer A. El-Aried ◽  
Shimaa M. G. Mansour ◽  
Reham M. ElBakrey ◽  
Abd El-Shakour N. Ismail ◽  
Amal A. M. Eid
Keyword(s):  
Avian Influenza ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Vaccine Efficacy ◽  
Infectious Bursal Disease Virus ◽  
Infectious Bursal Disease ◽  
Bursal Disease

scholarly journals Viral antibodies in south polar skuas around Davis Station, Antarctica

2008 ◽  
Vol 20 (5) ◽  
pp. 455-461 ◽  
Author(s):  
Gary D. Miller ◽  
Joanne M. Watts ◽  
Geoffrey R. Shellam
Keyword(s):  
Avian Influenza ◽  
Blood Serum ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Infectious Bursal Disease Virus ◽  
Infectious Bursal Disease ◽  
Viral Antibodies ◽  
Bursal Disease ◽  
Catharacta Maccormicki ◽  
South Polar

AbstractWe surveyed south polar skuas (Catharacta maccormickiSaunders) in Antarctica for antibodies to a series of viral agents using blood serum and cloacal swabs from 124 adult skuas. There were no ticks on the subjects and we were unable to isolate virus from any individual. Skuas, however, were seropositive to some avian viruses: 16.9% (20/118) had antibodies to infectious bursal disease virus and 10.5% (11/105) were seropositive for Newcastle disease. We found 1.0% (1/98) had antibodies to avian influenza, no evidence of egg drop syndrome (0/48), but 27.8% (10/36) had antibodies to flaviviruses. Clearly south polar skuas encounter a variety of pathogens either in Antarctica or during their migration in the non-breeding season. There was no evidence of disease in skuas, but the presence of antibodies to pathogens indicates the need to continue to search for the origins of these immunological challenges.

scholarly journals A Recombinant Newcastle Disease Virus (NDV) Expressing VP2 Protein of Infectious Bursal Disease Virus (IBDV) Protects against NDV and IBDV

2004 ◽  
Vol 78 (18) ◽  
pp. 10054-10063 ◽  
Author(s):  
Zhuhui Huang ◽  
Subbiah Elankumaran ◽  
Abdul S. Yunus ◽  
Siba K. Samal
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Recombinant Virus ◽  
Infectious Bursal Disease Virus ◽  
Antibody Responses ◽  
Infectious Bursal Disease ◽  
Vp2 Protein ◽  
Bursal Disease ◽  
Recombinant Newcastle Disease Virus

ABSTRACT Infectious bursal disease virus (IBDV) causes a highly immunosuppressive disease in chickens. Currently available, live IBDV vaccines can lead to generation of variant viruses. We have developed an alternative vaccine that will not create variant IBDV. By using the reverse genetics approach, we devised a recombinant Newcastle disease virus (NDV) vector from a commonly used vaccine strain LaSota to express the host-protective immunogen VP2 of a variant IBDV strain GLS-5. The gene encoding the VP2 protein of the IBDV was inserted into the most 3′-proximal locus of a full-length NDV cDNA for high-level expression. We successfully recovered the recombinant virus, rLaSota/VP2. The rLaSota/VP2 was genetically stable, at least up to 12 serial passages in chicken embryos, and was shown to express the VP2 protein. The VP2 protein was not incorporated into the virions of recombinant virus. Recombinant rLaSota/VP2 replicated to a titer similar to that of parental NDV strain LaSota in chicken embryos and cell cultures. To assess protective efficacy of the rLaSota/VP2, 2-day-old specific-pathogen-free chickens were vaccinated with the recombinant virus and challenged with a highly virulent NDV strain Texas GB or IBDV variant strain GLS-5 at 3 weeks postvaccination. Vaccination with rLaSota/VP2 generated antibody responses against both NDV and IBDV and provided 90% protection against NDV and IBDV. Booster immunization induced higher levels of antibody responses against both NDV and IBDV and conferred complete protection against both viruses. These results indicate that the recombinant NDV can be used as a vaccine vector for other avian pathogens.

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