Kummell's disease: Literature update and challenges ahead

Abstract Background: To evaluate the short to mid-term radiographic and clinical outcomes of the restoration of normal spinal alignment and sagittal balance in the treatment of Kümmell’s disease with thoracolumbar kyphosis. Methods: Between February 2016 and May 2018,30 cases of Kümmell’s disease with thoracolumbar kyphosis were divided into two groups (A and B) according to whether the kyphosis was combined with neurological deficits.All of the cases underwent surgical treatment to regain the normal spinal alignment and sagittal balance.And the radiographic outcomes and clinical results of these 30 patients were retrospectively evaluated.The sagittal imaging parameters including sagittal vertebral axis (SVA),thoracic kyphosis (TK),thoracolumbar kyphosis (TLK),lumbar lordosis (LL),pelvic incidence (PI),pelvic tilt (PT),and sacral slope (SS)of the whole spine before operation,immediately after operation,and the last follow-up of each group were measured and evaluated.The clinical results included the Oswestry Disability Index (ODI) and the Numerical Rating Scale (NRS) of the two groups .Results: The average follow-up period of group A and B were 34.2 and 38.7 months respectively.The parameters of both groups such as SVA,TLK,and thoracolumbar Cobb angle after surgery and at the last follow-up were significantly improved compared with those before surgery.The ODI and the NRS of the two groups at the last follow-up were also significantly improved. Conclusion: In the treatment of Kümmell’s disease with thoracolumbar kyphosis,to restore the normal alignment and sagittal balance can obtain a satisfactory radiographic and clinical short and medium-term effects.

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Kümmell’s disease: Is ischemic necrosis or vertebral “microcracking” the first step in the sequence?

Medical Hypotheses ◽

10.1016/j.mehy.2012.12.003 ◽

2013 ◽

Vol 80 (4) ◽

pp. 505 ◽

Cited By ~ 9

Author(s):

Charalampos Matzaroglou ◽

Christos S. Georgiou ◽

Hans Joachim Wilke ◽

Konstantinos Assimakopoulos ◽

Athanasios Karageorgos ◽

...

Keyword(s):

Ischemic Necrosis ◽

Kummell’S Disease ◽

Kümmell’S Disease

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Multiple Vertebral Osteonecroses (Kṻmmell’s Disease) After 10 Years on Denosumab: Is Osteocyte Apoptosis to Blame? More Evidence Needed

Calcified Tissue International ◽

10.1007/s00223-017-0386-9 ◽

2018 ◽

Vol 103 (1) ◽

pp. 109-110 ◽

Cited By ~ 1

Author(s):

Federica Biamonte ◽

Sudhaker D. Rao ◽

Cristiana Cipriani ◽

Jessica Pepe ◽

Piergianni Biondi ◽

...

Keyword(s):

Osteocyte Apoptosis ◽

Kummell’S Disease ◽

Kümmell’S Disease

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Comparison of the clinical outcomes and cement distribution patterns after percutaneous vertebroplasty in the treatment of thoracolumbar Kümmell’s disease and OVCFs

10.21203/rs.3.rs-19332/v1 ◽

2020 ◽

Author(s):

Cheng-Liang Wang ◽

Ji-Bin Chen ◽

Te Li

Keyword(s):

Bone Cement ◽

Distribution Pattern ◽

Operation Time ◽

Distribution Patterns ◽

Fracture Rate ◽

Vas Score ◽

Cement Distribution ◽

Kummell’S Disease ◽

Kümmell’S Disease ◽

Time Point

Abstract Background The purpose of this study is to investigate and compare the therapeutic effect and distribution characteristics of bone cement in the PVP treatment for thoracolumbar Kümmell's diseases and OVCFs. Methods A prospective analysis of 35 patients with Kümmell ’s disease (K group) and 35 patients with OVCFs (O group) who underwent PVP treatment from February 2016 to February 2018 was conducted. The vertebral compression rate and degree of osteoporosis were more serious in the K group than in the O group ( P <0.05, respectively). Distribution pattern, volume and leakage rate of bone cement, operation time, VAS score, ODI, correction rates of vertebral compression and kyphosis, re-fracture rate of adjacent vertebrae in 2 years between the two groups were compared to assess clinical effect. Results The follow-up time of the two groups was 24-48 months. The amount of intraoperative bone cement injection was significantly higher in the K group than in the O group ( P =0.025). The cement distribution pattern of local solid lump was dominant in the K group (65.71%), while intercalation with trabeculae was dominant in the O group (74.29%) ( P <0.001). VAS score and ODI were significantly lower both in the two groups at 1 day, 1 year and 2 years after surgery than before surgery (all P <0.05), but significantly lower in the K group than in the O group at each time point after surgery (all P <0.05). The correction rates of kyphosis and vertebral compression in both groups was significantly corrected ( P <0.05, respectively) and gradually lost with time ( P <0.05, respectively). The correction rates of kyphosis and vertebral compression were significantly higher in the K group than in the O group at each time point after surgery (all P <0.05). Conclusions PVP has the advantages of simple operation, short operation time, small trauma and quick recovery in treating both Kümmell's disease and OVCFs. However, PVP can better restore partial vertebral height and correct kyphosis in the treatment of Kümmell's disease, while can better alleviate pain and improve ODI in the treatment of OVCFs.

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