Case Study: Extension of a Systematic Data-Based Reinforcement System to Increase Independence in Public-School Inclusion Settings to a Student with Down Syndrome and Intellectual Disability

2018 ◽  
Vol 41 (3) ◽  
pp. 345-355
Author(s):  
Audrey Gifford ◽  
Caroline C. Redpath ◽  
Karen M. Lionello-DeNolf
Keyword(s):  
Down Syndrome ◽  
Intellectual Disability ◽  
Public School ◽  
Systematic Data ◽  
Reinforcement System

scholarly journals Mutations Impairing GSK3-Mediated MAF Phosphorylation Cause Cataract, Deafness, Intellectual Disability, Seizures, and a Down Syndrome-like Facies

2015 ◽  
Vol 96 (5) ◽  
pp. 816-825 ◽  
Author(s):  
Marcello Niceta ◽  
Emilia Stellacci ◽  
Karen W. Gripp ◽  
Giuseppe Zampino ◽  
Maria Kousi ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Intellectual Disability

Animal Models of Down Syndrome

2021 ◽  
Author(s):  
Anna J. Moyer ◽  
Roger H. Reeves
Keyword(s):  
Down Syndrome ◽  
Cognitive Impairment ◽  
Intellectual Disability ◽  
Animal Models ◽  
Brain Regions ◽  
Laboratory Mice ◽  
Tremendous Progress ◽  
New Treatments ◽  
And Function ◽  
Early Developmental

Is intellectual disability a treatable feature of persons with Down syndrome? Researchers have made tremendous progress in the last 30 years, from creating the first mouse model of Down syndrome to completing the first major clinical trial for cognitive impairment in people with Down syndrome. Until recently, normalizing brain development and function seemed too lofty a goal, and indeed, even proposing a candidate therapy requires answering a number of difficult questions. How does trisomy 21, a molecular diagnosis, cause the clinical phenotypes of Down syndrome? When, where, and how do trisomic genes act to disrupt normal development and which genes are involved with which outcomes? Which brain regions and behaviors are most impaired? Is there an early developmental window of time during which treatments are most effective? This article discusses how animal models such as laboratory mice can be used to understand intellectual disability and to develop new treatments for cognitive impairment.

Dancing with Down syndrome: a phenomenological case study

2015 ◽  
Vol 16 (3) ◽  
pp. 291-307 ◽  
Author(s):  
Nicole Reinders ◽  
Pamela J. Bryden ◽  
Paula C. Fletcher
Keyword(s):  
Down Syndrome ◽  
Phenomenological Case Study

A Case Study of the Virginia Head Start/Public School Transition Project

NHSA Dialog ◽  
1999 ◽  
Vol 2 (1) ◽  
pp. 116-119
Author(s):  
M. Jerry Cline ◽  
Frances Bridges-Cline
Keyword(s):  
Public School ◽  
Head Start ◽  
School Transition ◽  
Transition Project
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