Praliciguat. Soluble guanylate cyclase activator, Treatment of heart failure with preserved ejection fraction, Treatment of diabetic nephropathy

Preserved Ejection Fraction ◽

CINACIGUAT, A SOLUBLE GUANYLATE CYCLASE ACTIVATOR, UNLOADS THE HEART IN ACUTE DECOMPENSATED HEART FAILURE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(10)60148-9 ◽

2010 ◽

Vol 55 (10) ◽

pp. A16.E147 ◽

Cited By ~ 4

Author(s):

Erland Erdmann ◽

Marc J. Semigran ◽

Markku S. Nieminen ◽

Rahul Agrawal ◽

Veselin Mitrovic ◽

...

Keyword(s):

Heart Failure ◽

Guanylate Cyclase ◽

792 Cardiorenal actions of the new direct soluble guanylate cyclase activator BAY 58-2667 in experimental congestive heart failure

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(03)90524-8 ◽

2003 ◽

Vol 2 (1) ◽

pp. 172-173

Author(s):

G BOERRIGTER ◽

L COSTELLOBOERRIGTER ◽

A CATALIOTTI ◽

T TSURUDA ◽

G HARTY ◽

...

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Guanylate Cyclase ◽

Cardiorenal actions of the new heme-independent direct soluble guanylate cyclase activator BAY 58-2667 in experimental congestive heart failure

Journal of Cardiac Failure ◽

10.1016/s1071-9164(03)00214-8 ◽

2003 ◽

Vol 9 (5) ◽

pp. S9

Author(s):

Guido Boerrigter ◽

Lisa C. Costello-Boerrigter ◽

Harald Lapp ◽

Gail J. Harty ◽

Alessandro Cataliotti ◽

...

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Guanylate Cyclase ◽

BAY 58–2667, a soluble guanylate cyclase activator, improves cardiopulmonary haemodynamics in acute decompensated heart failure and has a favourable safety profile

BMC Pharmacology ◽

10.1186/1471-2210-7-s1-s9 ◽

2007 ◽

Vol 7 (S1) ◽

Cited By ~ 6

Author(s):

Harald Lapp ◽

Veselin Mitrovic ◽

Norbert Franz ◽

Hubertus Heuer ◽

Michael Buerke ◽

...

Keyword(s):

Heart Failure ◽

Guanylate Cyclase ◽

Safety Profile ◽

Favourable Safety ◽

Favourable Safety Profile ◽

Cinaciguat, a soluble guanylate cyclase activator, unloads the heart but also causes hypotension in acute decompensated heart failure†

European Heart Journal ◽

10.1093/eurheartj/ehs196 ◽

2012 ◽

Vol 34 (1) ◽

pp. 57-67 ◽

Cited By ~ 89

Author(s):

Erland Erdmann ◽

Marc J. Semigran ◽

Markku S. Nieminen ◽

Mihai Gheorghiade ◽

Rahul Agrawal ◽

...

Keyword(s):

Heart Failure ◽

Guanylate Cyclase ◽

The soluble guanylate cyclase activator BAY 58-2667 has a favourable safety profile and improves cardiopulmonary haemodynamics in acute decompensated heart failure

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(08)60005-3 ◽

2008 ◽

Vol 7 ◽

pp. 1-1 ◽

Cited By ~ 4

Author(s):

M MITROVIC ◽

H LAPP ◽

N FRANZ ◽

H HEUER ◽

M BUERKE ◽

...

Keyword(s):

Heart Failure ◽

Guanylate Cyclase ◽

Safety Profile ◽

Favourable Safety ◽

Favourable Safety Profile ◽

Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes

European Journal of Heart Failure ◽

10.1093/eurjhf/hfs093 ◽

2012 ◽

Vol 14 (9) ◽

pp. 1056-1066 ◽

Cited By ~ 75

Author(s):

Mihai Gheorghiade ◽

Stephen J. Greene ◽

Gerasimos Filippatos ◽

Erland Erdmann ◽

Roberto Ferrari ◽

...

Keyword(s):

Heart Failure ◽

Acute Heart Failure ◽

Guanylate Cyclase ◽

Randomized Controlled ◽

Acute Heart Failure Syndromes ◽

Patient-reported outcomes in the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED ejection fraction (SOCRATES-PRESERVED) study

European Journal of Heart Failure ◽

10.1002/ejhf.800 ◽

2017 ◽

Vol 19 (6) ◽

pp. 782-791 ◽

Cited By ~ 44

Author(s):

Gerasimos Filippatos ◽

Aldo P. Maggioni ◽

Carolyn S.P. Lam ◽

Elisabeth Pieske-Kraigher ◽

Javed Butler ◽

...

Keyword(s):

Heart Failure ◽

Ejection Fraction ◽

Guanylate Cyclase ◽

Patient Reported Outcomes ◽

Soluble Guanylate Cyclase Stimulator

Preserved Ejection Fraction ◽

Heart Failure Patients ◽

Patient Reported ◽

A Soluble Guanylate Cyclase Activator Inhibits the Progression of Diabetic Nephropathy in the ZSF1 Rat

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.115.230706 ◽

2016 ◽

Vol 356 (3) ◽

pp. 712-719 ◽

Cited By ~ 24

Author(s):

C. M. Boustany-Kari ◽

P. C. Harrison ◽

H. Chen ◽

K. A. Lincoln ◽

H. S. Qian ◽

...

Keyword(s):

Diabetic Nephropathy ◽

Guanylate Cyclase ◽

Population Pharmacokinetics and Pharmacodynamics of Cinaciguat, a Soluble Guanylate Cyclase Activator, in Patients with Acute Decompensated Heart Failure

Clinical Pharmacokinetics ◽

10.2165/11317590-000000000-00000 ◽

2010 ◽

Vol 49 (2) ◽

pp. 119-129 ◽

Cited By ~ 14

Author(s):

Wolfgang Mueck ◽

Reiner Frey

Keyword(s):

Heart Failure ◽

Population Pharmacokinetics ◽

Guanylate Cyclase ◽

Pharmacokinetics And Pharmacodynamics ◽

Population Pharmacokinetics And Pharmacodynamics ◽