scholarly journals Gene Expression of Bone Matrix Proteins and Endothelin Receptors in Endothelin-1-Deficient Mice Revealed by In Situ Hybridization

1998 ◽  
Vol 13 (2) ◽  
pp. 237-244 ◽  
Author(s):  
Yukie Kitano ◽  
Hiroki Kurihara ◽  
Yukiko Kurihara ◽  
Koji Maemura ◽  
Yoshimi Ryo ◽  
...  
Keyword(s):  
Gene Expression ◽  
In Situ Hybridization ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Endothelin Receptors ◽  
Endothelin 1 ◽  
Bone Matrix Proteins ◽  
Deficient Mice

Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization

2009 ◽  
Vol 9 (10) ◽  
pp. 1551-1557 ◽  
Author(s):  
Kimiaki Hirakawa ◽  
Sehchi Hirota ◽  
Tohru Ikeda ◽  
Akira Yamaguchi ◽  
Teiji Takemura ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fracture Healing ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Bone Matrix Proteins

scholarly journals In situ hybridization of bone matrix proteins in undecalcified adult rat bone sections.

1992 ◽  
Vol 40 (8) ◽  
pp. 1079-1088 ◽  
Author(s):  
T Ikeda ◽  
S Nomura ◽  
A Yamaguchi ◽  
T Suda ◽  
S Yoshiki
Keyword(s):  
In Situ Hybridization ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Adult Rat ◽  
Bone Matrix Proteins ◽  
Rat Bone

PERIARTICULAR GENE EXPRESSION OF OSTEOPONTIN AND PROGRESSION IN OSTEOPENIA FOLLOWING JOINT IMMOBILIZATION

2001 ◽  
Vol 05 (04) ◽  
pp. 225-234
Author(s):  
TAKAHIDE MIYAMA ◽  
NORIMASA NAKAMURA ◽  
TAKANOBU NAKASE ◽  
YUKIYOSHI TORITSUKA ◽  
AKIRA MYOUI ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Matrix ◽  
Knee Joints ◽  
Tartrate Resistant Acid Phosphatase ◽  
Positive Staining ◽  
Multinucleated Cells ◽  
Molecular Events ◽  
Bone Matrix Proteins ◽  
Temporal And Spatial

In order to elucidate the molecular events involved in periarticular osteopenia following joint immobilization, we investigated the temporal and spatial gene expression of one of the major non-collagenous bone matrix proteins, osteopontin (OPN), in periarticular regions, after immobilizing rat knee joints. Significant decreases in total BMD was observed in the immobilized limbs after 2 weeks of immobilization. Histologically, multinucleated cells with positive staining for tartrate resistant acid phosphatase (TRAP) were significantly increased in the metaphyseal regions, 1 to 4 weeks following immobilization. In situ hybridization studies revealed that OPN mRNA was present in a significantly larger number of cells in the metaphysial regions of joints immobilized for 1 to 3 weeks; compared with those levels detected in the control limbs, OPN mRNA was mainly detected in osteoblast/osteocyte-lineage cells of the spongiosa. Such temporal and spatial similarities in the expression of TRAP-positive multinucleated cells and OPN transcripts suggest the possible involvement of OPN in the periarticular osteoclastogenesis, leading to the activation of regional bone resorption following joint immobilization.

scholarly journals Altered distribution of bone matrix proteins and defective bone mineralization in klotho-deficient mice

Bone ◽  
2013 ◽  
Vol 57 (1) ◽  
pp. 206-219 ◽  
Author(s):  
Muneteru Sasaki ◽  
Tomoka Hasegawa ◽  
Tamaki Yamada ◽  
Hiromi Hongo ◽  
Paulo Henrique Luiz de Freitas ◽  
...  
Keyword(s):  
Bone Mineralization ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Bone Matrix Proteins ◽  
Defective Bone ◽  
Deficient Mice

scholarly journals Gene expression for bone matrix proteins during bone resorption in calcium-deficient rats.

1994 ◽  
Vol 64 ◽  
pp. 290
Author(s):  
Keiichi Ohya ◽  
Maki Sumikawa ◽  
Naoya Arai ◽  
Masashi Tatematsu ◽  
Hideaki Ogura
Keyword(s):  
Gene Expression ◽  
Bone Resorption ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Bone Matrix Proteins

Gene Expression of Noncollagenous Bone Matrix Proteins in the Limb Joints and Intervertebral Disks of the twy Mouse

1998 ◽  
Vol 63 (2) ◽  
pp. 167-172 ◽  
Author(s):  
T. Ohtsuki ◽  
S. Furuya ◽  
T. Yamada ◽  
S. Nomura ◽  
J.-i. Hata ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Intervertebral Disks ◽  
Bone Matrix Proteins
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