Evolutionary Ttrace analysis of eukaryotic DNA topoisomerase I superfamily: Identification of novel antitumor drug binding site

2005 ◽  
Vol 48 (4) ◽  
pp. 375 ◽  
Author(s):  
Yunlong SONG
Keyword(s):  
Binding Site ◽  
Topoisomerase I ◽  
Antitumor Drug ◽  
Drug Binding ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Drug Binding Site ◽  
Eukaryotic Dna

Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives

2013 ◽  
Vol 23 (1) ◽  
pp. 480-486 ◽  
Author(s):  
Fatma Zilifdar ◽  
Sabiha Alper-Hayta ◽  
Serap Yilmaz ◽  
Çiğdem Kaplan-Özen ◽  
Egemen Foto ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Inhibitory Effects ◽  
Dna Topoisomerase ◽  
Eukaryotic Dna

scholarly journals Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site.

1990 ◽  
Vol 265 (31) ◽  
pp. 19287-19295
Author(s):  
R.P. Hertzberg ◽  
R.W. Busby ◽  
M.J. Caranfa ◽  
K.G. Holden ◽  
R.K. Johnson ◽  
...  
Keyword(s):  
Binding Site ◽  
Topoisomerase I ◽  
Affinity Labeling ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Covalent Complex

Minor groove dimeric bisbenzimidazoles inhibit in vitro DNA binding to eukaryotic DNA topoisomerase I

2010 ◽  
Vol 75 (6) ◽  
pp. 695-701 ◽  
Author(s):  
O. Yu. Susova ◽  
A. A. Ivanov ◽  
S. S. Morales Ruiz ◽  
E. A. Lesovaya ◽  
A. V. Gromyko ◽  
...  
Keyword(s):  
Dna Binding ◽  
Topoisomerase I ◽  
Minor Groove ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Dimeric Bisbenzimidazoles ◽  
Eukaryotic Dna

DNA recombinase activity of eukaryotic DNA topoisomerase I; effects of camptothecin and other inhibitors

1995 ◽  
Vol 337 (2) ◽  
pp. 135-145 ◽  
Author(s):  
Yves Pommier ◽  
Jeffrey Jenkins ◽  
Glenda Kohlhagen ◽  
François Leteurtre
Keyword(s):  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Eukaryotic Dna ◽  
Dna Recombinase

Differential Stabilization of Eukaryotic DNA Topoisomerase I Cleavable Complexes by Camptothecin Derivatives

Biochemistry ◽  
1995 ◽  
Vol 34 (21) ◽  
pp. 7200-7206 ◽  
Author(s):  
Akihiko Tanizawa ◽  
Kurt W. Kohn ◽  
Glenda Kohlhagen ◽  
Francois Leteurtre ◽  
Yves Pommier
Keyword(s):  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Dna Topoisomerase ◽  
Eukaryotic Dna
Sign in / Sign up

Export Citation Format

Share Document