A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

PLoS Genetics ◽

10.1371/journal.pgen.1006185 ◽

2016 ◽

Vol 12 (7) ◽

pp. e1006185 ◽

Author(s):

Sahar Kassem ◽

Guillaume Gaud ◽

Isabelle Bernard ◽

Mehdi Benamar ◽

Anne S. Dejean ◽

...

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

Signaling Molecule ◽

Effector T Cell ◽

Cell Functions ◽

T Cell Receptor Signaling ◽

Natural Variant ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of T cell receptor signaling precedes immunological synapse formation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004974.58104 ◽

2002 ◽

Author(s):

Andre Veillette

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Synapse Formation ◽

Immunological Synapse ◽

Cell Receptor ◽

Receptor Signaling ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Regulation of T cell receptor signaling by activation-induced zinc influx.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10059956.11264055 ◽

2011 ◽

Author(s):

Donna Farber ◽

Minjun Yu

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13373008.15147061 ◽

2012 ◽

Author(s):

Elizabeth Mellins ◽

Michael Strohman

Keyword(s):

Major Histocompatibility Complex ◽

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

Major Histocompatibility ◽

Histocompatibility Complex ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of The Ca(v)1.4 calcium channel is a critical regulator of T cell receptor signaling and naive T cell homeostasis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13411045.14782172 ◽

2011 ◽

Author(s):

Markus Hoth

Keyword(s):

T Cell ◽

Calcium Channel ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

T Cell Homeostasis ◽

Cell Homeostasis ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling ◽

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Faculty Opinions recommendation of Distinct temporal patterns of T cell receptor signaling during positive versus negative selection in situ.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718145624.793487806 ◽

2013 ◽

Author(s):

Valerie Horsley ◽

Natalie Roberts

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Negative Selection ◽

Temporal Patterns ◽

Cell Receptor ◽

Receptor Signaling ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.723619637.793515738 ◽

2016 ◽

Author(s):

Miguel Vicente-Manzanares

Keyword(s):

T Cell ◽

Programmed Cell Death ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

Programmed Cell Death 1 ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726375245.793551467 ◽

2018 ◽

Author(s):

Andrea Reboldi

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Membrane Cholesterol ◽

Receptor Signaling ◽

Cholesterol Sulfate ◽

Naturally Occurring ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Faculty Opinions recommendation of Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726922889.793528475 ◽

2017 ◽

Author(s):

Benjamin Kile

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

T Cell Exhaustion ◽

Receptor Signaling ◽

Cell Exhaustion ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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Strength of T Cell Receptor Signaling Strikes Again

Immunity ◽

10.1016/j.immuni.2009.09.008 ◽

2009 ◽

Vol 31 (4) ◽

pp. 529-531 ◽

Author(s):

Leslie J. Berg

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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A Biophysical Mechanosensor Model for T-Cell Receptor Signaling

Biophysical Journal ◽

10.1016/j.bpj.2008.12.1981 ◽

2009 ◽

Vol 96 (3) ◽

pp. 368a

Author(s):

Zhen-Yu J. Sun ◽

SunTaek Kim ◽

Koh Takeuchi ◽

Maki Touma ◽

Jiahuai Wang ◽

...

Keyword(s):

T Cell ◽

T Cell Receptor ◽

Cell Receptor ◽

Receptor Signaling ◽

T Cell Receptor Signaling ◽

Cell Receptor Signaling

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