scholarly journals Antibiotic Selection Pressure and Macrolide Resistance in Nasopharyngeal Streptococcus pneumoniae: A Cluster-Randomized Clinical Trial

PLoS Medicine ◽  
2010 ◽  
Vol 7 (12) ◽  
pp. e1000377 ◽  
Author(s):  
Alison H. Skalet ◽  
Vicky Cevallos ◽  
Berhan Ayele ◽  
Teshome Gebre ◽  
Zhaoxia Zhou ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Streptococcus Pneumoniae ◽  
Randomized Clinical Trial ◽  
Selection Pressure ◽  
Macrolide Resistance ◽  
Antibiotic Selection ◽  
Antibiotic Selection Pressure ◽  
Cluster Randomized

scholarly journals Using increased trust in medical researchers to increase minority recruitment: The RECRUIT cluster randomized clinical trial

2021 ◽  
pp. 106519
Author(s):  
Barbara C. Tilley ◽  
Arch G. Mainous ◽  
Rossybelle P. Amorrortu ◽  
M. Diane McKee ◽  
Daniel W. Smith ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Minority Recruitment ◽  
Medical Researchers ◽  
Cluster Randomized

Is the future for clinical trials internet-based? A cluster randomized clinical trial

2005 ◽  
Vol 2 (1) ◽  
pp. 72-79 ◽  
Author(s):  
Jennifer Litchfield ◽  
Jenny Freeman ◽  
Henrik Schou ◽  
Mark Elsley ◽  
Robert Fuller ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Randomized Clinical Trial ◽  
The Future ◽  
Cluster Randomized

scholarly journals Postvaccination Increase in Serotype 19A Pneumococcal Disease in Norway Is Driven by Expansion of Penicillin-Susceptible Strains of the ST199 Complex

2012 ◽  
Vol 19 (3) ◽  
pp. 443-445 ◽  
Author(s):  
Didrik F. Vestrheim ◽  
Martin Steinbakk ◽  
Ingeborg S. Aaberge ◽  
Dominique A. Caugant
Keyword(s):  
Conjugate Vaccine ◽  
Invasive Pneumococcal Disease ◽  
Pneumococcal Conjugate Vaccine ◽  
Selection Pressure ◽  
Pneumococcal Disease ◽  
Antibiotic Selection ◽  
Serotype Replacement ◽  
Rapid Replacement ◽  
Antibiotic Selection Pressure

ABSTRACTSerotype replacement in invasive pneumococcal disease has been observed after widespread use of the 7-valent pneumococcal conjugate vaccine (PCV7). Replacement is dominated by penicillin-nonsusceptible serotype 19A in several countries. Antibiotic selection pressure has been proposed to interact with immunization, leading to rapid replacement. In Norway, where prescription of antibiotics is limited, post-PCV7 replacement by serotype 19A is dominated by penicillin-susceptible clones. Hence, serotype 19A replacement occurs, although it is not driven by antibiotic selection pressure.

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