scholarly journals Rapid pathogen identification and antimicrobial susceptibility testing in in vitro endophthalmitis with matrix assisted laser desorption-ionization Time-of-Flight Mass Spectrometry and VITEK 2 without prior culture

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0227071 ◽  
Author(s):  
Lindsay Y. Chun ◽  
Laura Dolle-Molle ◽  
Cindy Bethel ◽  
Rose C. Dimitroyannis ◽  
Blake L. Williams ◽  
...  
Keyword(s):  
Susceptibility Testing ◽  
Laser Desorption ◽  
Laser Desorption Ionization ◽  
Pathogen Identification ◽  
Ionization Time ◽  
Flight Mass Spectrometry ◽  
Vitek 2 ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption

scholarly journals Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Accelerates Pathogen Identification and May Confer Benefit in the Outcome of Peritoneal Dialysis-Related Peritonitis

2016 ◽  
Vol 54 (5) ◽  
pp. 1381-1383 ◽  
Author(s):  
Wei-Hung Lin ◽  
Jyh-Chang Hwang ◽  
Chin-Chung Tseng ◽  
Yu-Tzu Chang ◽  
An-Bang Wu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Laser Desorption ◽  
Laser Desorption Ionization ◽  
Pathogen Identification ◽  
Ionization Time ◽  
Desorption Ionization ◽  
Flight Mass Spectrometry ◽  
Tof Ms ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption

Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) and conventional standard methods were compared for time to pathogen identification and impact on clinical outcomes in peritoneal dialysis-related peritonitis patients. The MALDI-TOF MS method identified the causative microorganisms earlier (average time saved, 64 h for all pathogens), and patients had a shorter hospital stay (mean ± standard deviation, 5.2 ± 4.8 days versus 8.2 ± 4.5 days,P= 0.001).

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