Spontaneous Dissection of Three Major Coronary Arteries Subsequent to Cystic Medial Necrosis

CHEST Journal ◽  
1999 ◽  
Vol 116 (5) ◽  
pp. 1473-1475 ◽  
Author(s):  
Viviane M. Conraads ◽  
Anne Vorlat ◽  
Cecile G. Colpaert ◽  
Inez E. Rodrigus ◽  
Rudi J. De Paep ◽  
...  
Keyword(s):  
Coronary Arteries ◽  
Cystic Medial Necrosis ◽  
Medial Necrosis ◽  
Spontaneous Dissection

scholarly journals Pathology of Spontaneous Dissection of Intracranial Arteries

1987 ◽  
Vol 14 (S1) ◽  
pp. 88-91 ◽  
Author(s):  
John H.N. Deck
Keyword(s):  
Internal Carotid ◽  
Cerebral Arteries ◽  
Internal Elastic Lamina ◽  
Cystic Medial Necrosis ◽  
Vertebrobasilar System ◽  
Moya Moya Disease ◽  
Medial Necrosis ◽  
The Media ◽  
And Control ◽  
Spontaneous Dissection

ABSTRACT:Spontaneous dissection of a major subarachnoid artery is an uncommon cause of stroke in young and apparently healthy individuals. Such dissection does not correlate well with systemic conditions such as emboli, thrombotic or hemorrhagic tendencies or hypertension, nor with disease of blood vessels such as atherosclerosis, fibromuscular dysplasia, cystic medial necrosis or Moya-Moya disease. Unusual exertion has been implicated as a factor in some cases. Gap defects were found in the internal elastic lamina near the site of dissection in three of four cases of spontaneous dissection reported here. It is suggested that such defects, because of their unusual size or number, may be responsible for initiating dissection in susceptible individuals. A detailed study of the major cerebral arteries in cases of dissection and control cases to document the size and frequency of such defects could shed light on the pathogenesis of spontaneous dissection. The subsequent course of events tends to differ in the internal carotid and vertebro-basilar systems. In most cases, the dissection in the internal carotid system is sub-intimal leading to thrombosis and cerebral infarction, while in the vertebrobasilar system dissection lies between the media and adventitia leading to subarachnoid hemorrhage. It is not known what structural differences of the two arterial systems may underlie this difference in the pattern of arterial dissection.

Cystic medial necrosis Erdheim-Gsell

VASA ◽  
2011 ◽  
Vol 40 (4) ◽  
pp. 336-337
Author(s):  
Leu ◽  
Gary ◽  
Brodmann
Keyword(s):  
Cystic Medial Necrosis ◽  
Medial Necrosis

scholarly journals Fatal aorticMyceliophthora thermophilainfection in a patient affected by cystic medial necrosis

1998 ◽  
Vol 36 (2) ◽  
pp. 113-118
Author(s):  
C. Farina ◽  
A. Gamba ◽  
R. Tambini ◽  
H. Beguin ◽  
J.L. Trouillet
Keyword(s):  
Cystic Medial Necrosis ◽  
Medial Necrosis

CYSTIC MEDIAL NECROSIS AND DISSECTING CEREBRAL ANEURYSMS

1990 ◽  
Vol 49 (3) ◽  
pp. 301
Author(s):  
D. P. Fosmire ◽  
L. Pitts ◽  
C. Jacques ◽  
C. M. Greco
Keyword(s):  
Cerebral Aneurysms ◽  
Cystic Medial Necrosis ◽  
Medial Necrosis

Genetic diseases of the aorta: aortic diseases associated with bicuspid aortic valves

ESC CardioMed ◽  
2018 ◽  
pp. 2613-2615
Author(s):  
Folkert Meijboom ◽  
Gert-Jan Sieswerda
Keyword(s):  
Aortic Wall ◽  
Structural Integrity ◽  
Genetic Diseases ◽  
Basic Research ◽  
Ascending Aorta ◽  
Flow Profile ◽  
Aortic Diseases ◽  
Cystic Medial Necrosis ◽  
Medial Necrosis ◽  
Genetically Determined

There is a genetic cause of bicuspid aortic valve. Dilatation of the aortic root and ascending aorta has long been considered genetically determined too and treated accordingly. In recent years, basic research combined with advanced cardiac imaging has made a strong case for another cause of this dilatation: an altered flow profile in the ascending aorta due to the abnormal geometry of the bicuspid valve, leading to an area of altered wall shear stress, which in turn leads to remodelling of the aortic wall, with apoptosis of vascular smooth muscle cells and disruption of media layer as a result. These histological changes, previously referred to as cystic medial necrosis, form the basis of a loss of structural integrity of the aortic wall, which makes it prone to dilatation, dissection, and rupture.

Giant Circumflex Coronary Artery Aneurysm Associated With Cystic Medial Necrosis in a Non-Marfan Patient

2007 ◽  
Vol 83 (2) ◽  
pp. 668-670 ◽  
Author(s):  
Koji Takeda ◽  
Goro Matsumiya ◽  
Motonobu Nishimura ◽  
Hajime Matsue ◽  
Yasuhiko Tomita ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Aneurysm ◽  
Artery Aneurysm ◽  
Circumflex Coronary Artery ◽  
Cystic Medial Necrosis ◽  
Medial Necrosis ◽  
Marfan Patient

Cystic Medial Necrosis

1974 ◽  
Vol 109 (1) ◽  
pp. 84 ◽  
Author(s):  
Arthur J. Roberts
Keyword(s):  
Cystic Medial Necrosis ◽  
Medial Necrosis
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