Cerebral Venous Sinus Thrombosis as a Complication of Inflammatory Bowel Disease: A Case Report

2010 ◽  
Vol 105 ◽  
pp. S358-S359
Author(s):  
Ashish Kumar ◽  
Rajesh Panchwagh ◽  
Harsh Goel
Keyword(s):  
Inflammatory Bowel Disease ◽  
Case Report ◽  
Bowel Disease ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Inflammatory Bowel

scholarly journals Cerebral Venous Sinus Thrombosis in a Patient with Ulcerative Colitis Flare

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
L. M. Conners ◽  
R. Ahad ◽  
P. H. Janda ◽  
Z. Mudasir
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Increased Risk ◽  
Inflammatory Bowel

Inflammatory bowel disease is characterized by a chronic inflammatory state and is therefore associated with abnormalities in coagulation and a hypercoagulable state. Cerebral venous sinus thrombosis is a rare complication of inflammatory bowel disease yet contributes significant morbidity and mortality to those affected. Early diagnosis is critical, as a delay in diagnosis portends a worse prognosis. This paper seeks to highlight the increased risk of venous sinus thrombosis in patients with inflammatory bowel disease. We start by discussing the case of a seventeen-year-old female who presented with ulcerative colitis flare and developed new-onset seizures, found to be caused by a large venous sinus thrombosis.

scholarly journals Cerebral Venous Sinus Thrombosis in Patients With Inflammatory Bowel Disease: A Retrospective Study

2021 ◽  
Author(s):  
Wang Shujun ◽  
Zhang Huijie ◽  
Bai Xia ◽  
Wang Hongjian
Keyword(s):  
Risk Factors ◽  
Inflammatory Bowel Disease ◽  
Clinical Data ◽  
Bowel Disease ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Speech Impairment ◽  
Venous Sinus Thrombosis ◽  
Inflammatory Bowel

Abstract BACKGROUND: Cerebral venous sinus thrombosis (CVST) is a rare and devastating complication of inflammatory bowel disease (IBD). Early diagnose and prompt treatment could improve prognosis.AIM: The aim of our study was to investigate the clinical data and risk factors of inflammatory bowel disease with diagnosis of CVST. METHODS: All data of IBD patients were collected from July 2013 and September 2020. Clinical data, risk factors and prognosis were compared between CVST in IBD patients and IBD control group. RESULTS: The incidence of CVST in our study was 0.48%. The mean age of IBD patients with CVST was 34.9 years. Average disease duration of IBD was 4 years when cerebrovascular events occur. Clinical presentation of CVST included headache (73.1%), vomiting (30.8%), limb dysmetria (26.9%), speech impairment (11.5%), blurred vision (7.7%), Epileptic seizures (7.7%) and drowsiness (3.8%). The most common location for CVST was transverse sinus (61.5%), followed by superior sagittal sinus (30.8%). Anemia, low albumin and elevated D-dimer were independent predictors of CVST in IBD patients. Anticoagulation therapy was effective. Prognosis of IBD patients with CVST was worse than those without CVST.CONCLUSION: Early identification the risk of and clinical features of CVST in IBD patients is important. Prompt antithrombotic therapy is safe and effective treatment.

scholarly journals Cerebral venous sinus thrombosis in patients with inflammatory bowel disease: a retrospective study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wang Shujun ◽  
Zhang Huijie ◽  
Bai Xia ◽  
Wang Hongjian
Keyword(s):  
Inflammatory Bowel Disease ◽  
Clinical Data ◽  
Predictive Factors ◽  
Bowel Disease ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Speech Impairment ◽  
Venous Sinus Thrombosis ◽  
Inflammatory Bowel

AbstractCerebral venous sinus thrombosis (CVST) is a rare and devastating complication of inflammatory bowel disease (IBD). Early diagnosis and prompt treatment could improve prognosis. The aim of our study was to investigate the clinical data and predictive factors of inflammatory bowel disease in patients with a diagnosis of CVST. All IBD patient data were collected from July 2013 and September 2020. Clinical data, predictive factors and prognosis were compared between IBD patients with CVST and the IBD control group. The incidence of CVST in our study was 0.48%. The mean age of IBD patients with CVST was 34.9 years. The average duration of IBD was 4 years when cerebrovascular events occurred. The clinical presentation of CVST included headache (73.1%), vomiting (30.8%), limb dysmetria (26.9%), speech impairment (11.5%), blurred vision (7.7%), epileptic seizures (7.7%) and drowsiness (3.8%). The most common location for CVST was the transverse sinus (61.5%) followed by the superior sagittal sinus (30.8%). Anaemia, low albumin and elevated d-dimer were independent predictors of CVST in patients with IBD. Anticoagulation therapy was effective. The prognosis of IBD patients with CVST was worse than that of IBD patients without CVST. Early identification of the risk and clinical features of CVST in IBD patients is important. Prompt antithrombotic therapy is a safe and effective treatment.

Abstract TP182: Risk of Acute Ischemic Stroke Increases During Severe Flares of Inflammatory Bowel Disease

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Benjamin R Kummer ◽  
Alexander E Merkler ◽  
Gino Gialdini ◽  
Hooman Kamel
Keyword(s):  
Inflammatory Bowel Disease ◽  
Ischemic Stroke ◽  
Bowel Disease ◽  
Sinus Thrombosis ◽  
Thrombotic Event ◽  
Venous Sinus ◽  
Index Hospitalization ◽  
Venous Sinus Thrombosis ◽  
Increased Risk ◽  
Inflammatory Bowel

Introduction: Flares of inflammatory bowel disease (IBD) have been associated with venous thromboembolism, and recent studies suggest an association between IBD and myocardial infarction. The association between IBD flares and cerebral thrombotic disease is less clear. We therefore sought to evaluate the risk of cerebral venous and arterial stroke during IBD flares. Hypothesis: IBD flares are associated with an increased risk of a cerebral thrombotic event. Methods: We used data on all admissions at nonfederal acute care hospitals in California, Florida, and New York to identify patients with a primary ICD-9-CM diagnosis code for ulcerative colitis or Crohn’s disease between 2005 and 2012. Patients with a documented abdominal surgery during the index hospitalization were excluded. An IBD flare was defined as a period of 120 days from the start of the index IBD-related hospitalization. Our outcomes were ischemic stroke and cerebral venous sinus thrombosis. We used a self-controlled case series design in which we compared the risk of a thrombotic event in the 120 days after hospitalization versus the risk during the 120 days prior to hospitalization. Results: We identified 31,993 patients with IBD, of whom 98 (0.31%) developed ischemic stroke. As compared with the control period preceding the index hospitalization, the risk of stroke was significantly elevated during the 120 days after IBD-related hospitalization (incidence rate ratio [IRR] 2.0; 95% confidence interval [CI] 1.3-3.0). In subgroup analyses, this elevated risk was apparent only in the 16,280 patients older than the median age of 44 years (IRR 1.9; 95% CI, 1.27-2.95), and not in the 15,713 patients younger than 44 years of age, among whom we identified only one stroke. We found only one patient with a documented venous sinus thrombosis and thus could not estimate the risk associated with an IBD flare. Conclusion: We found an association between IBD-related hospitalization and the risk of ischemic stroke in older patients. These results build on recent studies suggesting an association between IBD and the risk of arterial thrombotic events. Further research is needed to better define the association between IBD and cerebrovascular events, especially rare events such as cerebral sinus thrombosis.

scholarly journals Catatonia, beyond a psychiatric syndrome

2017 ◽  
Vol 11 (2) ◽  
pp. 209-212
Author(s):  
Nathália Stela Visoná de Figueiredo ◽  
Débora Bartzen Moraes Angst ◽  
Antônio de Matos Lima Neto ◽  
Michel Ferreira Machado ◽  
Maria Sheila Guimarães Rocha ◽  
...  
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Clinical Manifestation ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Nonconvulsive Status Epilepticus ◽  
Diagnostic Investigation ◽  
Venous Sinus Thrombosis ◽  
Psychiatric Syndrome

ABSTRACT Although catatonia is a well-known psychiatric syndrome, there are many possible systemic and neurological etiologies. The aim of this case report was to present a case of a patient with cerebral venous sinus thrombosis and infarction in which catatonia was the clinical manifestation of a possible nonconvulsive status epilepticus. To our knowledge, only one such case has been reported in the literature, which had a simplified diagnostic investigation. It is important to correctly recognize the organic cause underlying catatonia in order to treat the patient as soon as possible thereby improving outcome. Therefore, physicians need to update their knowledge on catatonia, recognizing that it can be part of a psychiatric or neurologic condition.

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