The Proton Pump Inhibitor Time Problem: A Quality Improvement Pilot Study

2013 ◽  
Vol 108 ◽  
pp. S494
Author(s):  
Niket Sonpal ◽  
Raji Shameem ◽  
Robert Graham
2021 ◽  
Vol 5 (1) ◽  
pp. 19
Author(s):  
Adriana M. L. Ferraz ◽  
Susana Bandarra ◽  
Paulo Mascarenhas ◽  
Isabel Barahona ◽  
Rui Martins ◽  
...  

The interindividual variability of Proton Pump Inhibitor (PPI) therapy results from the phenotype variability associated with the cytochrome P450 2C19 (CYP2C19) gene, namely the CYP2C19*17 allele. Our aim was to characterize patients’ genetic variability undergoing PPI therapy. A sample of 33 oral mucosa cells from Portuguese pharmacy patients was collected, followed by genotyping. The allelic frequencies of CYP2C19*1 (-806C) and CYP2C19*17 (-806T) were 71.2% and 28.8%, respectively. The genotypic frequencies for CYP2C19*1/*1 and CYP2C19*1/*17 were 42.4% and 57.6%, respectively, and 19 of these patients may have a Rapid Metabolizer (RM) phenotype pharmaceutical opinion letter, based on genetic evidence.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Angela Horvath ◽  
Bettina Leber ◽  
Nicole Feldbacher ◽  
Markus Steinwender ◽  
Irina Komarova ◽  
...  

2020 ◽  
Vol 158 (6) ◽  
pp. S-1000-S-1001
Author(s):  
Prateek Mathur ◽  
Taylor Rider ◽  
Paridhi Malik ◽  
Anisleidys Munoz ◽  
Erik Olson

Gut and Liver ◽  
2016 ◽  
Vol 10 (6) ◽  
pp. 896-901 ◽  
Author(s):  
Cheol Min Shin ◽  
Nayoung Kim ◽  
Yong Sung Kim ◽  
Ryoung Hee Nam ◽  
Ji Hyun Park ◽  
...  

2012 ◽  
Vol 60 (6) ◽  
pp. 362 ◽  
Author(s):  
Jeong Hwan Yoo ◽  
Chang-Il Kwon ◽  
Kwang-Ho Yoo ◽  
Harry Yoon ◽  
Won Hee Kim ◽  
...  

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