A Rare Case of Metastatic Prostate Carcinoma Presenting as Obstructive Jaundice

✓ Despite the relatively high incidence of prostate carcinoma involving the spinal column, those that are associated with spinal intradural extramedullary metastases are rare. The role of surgery for metastases to this spinal compartment is limited and palliative because presentation tends to be late in the course of the disease, particularly for prostate carcinoma. It is also considered to be part of the spectrum of leptomeningeal carcinomatosis and is associated with a high incidence of brain metastases. The authors review a rare case of prostate carcinoma metastatic to the spinal intradural extramedullary space and discuss its clinical presentation, imaging features, and surgical management.

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Pulmonary Tumor Thrombotic Microangiopathy from Metastatic Prostate Carcinoma

Case Reports in Pulmonology ◽

10.1155/2015/286962 ◽

2015 ◽

Vol 2015 ◽

pp. 1-3

Author(s):

Dhruv Nayyar ◽

Kavitha Muthiah ◽

Christopher S. Hayward ◽

Zerlene Lim ◽

Emily K. Granger ◽

...

Keyword(s):

Gastric Adenocarcinoma ◽

Prostate Carcinoma ◽

Thrombotic Microangiopathy ◽

Prostate Adenocarcinoma ◽

Respiratory Complication ◽

Pulmonary Tumor ◽

Pulmonary Tumor Thrombotic Microangiopathy ◽

Metastatic Prostate Carcinoma

Pulmonary tumor thrombotic microangiopathy is a rare but serious malignancy-related respiratory complication. The most common causative neoplasm is gastric adenocarcinoma. We report a case caused by metastatic prostate adenocarcinoma, diagnosed postmortem in a 58-year-old male. To our knowledge, this is the second reported case from metastatic prostate adenocarcinoma.

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The dedifferentiation of metastatic prostate carcinoma

British Journal of Cancer ◽

10.1038/bjc.1989.16 ◽

1989 ◽

Vol 59 (1) ◽

pp. 85-88 ◽

Cited By ~ 27

Author(s):

PN Brawn ◽

VO Speights

Keyword(s):

Prostate Carcinoma ◽

Metastatic Prostate Carcinoma

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Mucin-filled CBD, difficult to manage cholangitis

BMJ Case Reports ◽

10.1136/bcr-2020-238363 ◽

2021 ◽

Vol 14 (1) ◽

pp. e238363

Author(s):

Manish Kumar ◽

Ujjwal Sonika ◽

Sanjeev Sachdeva ◽

Ashok Dalal

Keyword(s):

Bile Duct ◽

Common Bile Duct ◽

Obstructive Jaundice ◽

Rare Case ◽

Malignant Potential ◽

Cystic Neoplasm ◽

Stricture Formation ◽

Intraductal Papillary Mucinous Neoplasms ◽

Mucinous Neoplasms ◽

Optimum Management

Intraductal papillary mucinous neoplasms (IPMNs) are mucin-secreting cystic neoplasm of pancreas. They have a malignant potential. They are usually localised to the pancreas but occasionally can involve surrounding structures (1.9%–6.6%), like bile duct and duodenum, and are labelled as IPMN with invasion. Jaundice as a manifestation of IPMN is not common (4.5%). It can present as jaundice as a result of invasion of common bile duct (CBD) resulting in stricture formation or uncommonly as a result of fistulising to CBD with resultant obstruction of CBD by thick mucin secreted by this tumour. As only few cases (around 23) of mucin-filled CBD are reported in the literature. We are presenting our experience in dealing a rare case of obstructive jaundice caused by IPMN fistulising into CBD, highlighting the difficulties faced in managing such case, especially with regards to biliary drainage and what can be the optimum management in such cases.

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