Different Stability of Free and Complexed Prostate-Specific Antigen in Serum in Relation to Specimen Handling and Storage Conditions

2000 ◽  
Vol 38 (12) ◽  
Author(s):  
Klaus Jung ◽  
Michael Lein ◽  
Brigitte Brux ◽  
Pranav Sinha ◽  
Dietmar Schnorr ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Storage Conditions ◽  
Specimen Handling ◽  
And Storage

scholarly journals Preanalytical Determinants of Total and Free Prostate-Specific Antigen and Their Ratio: Blood Collection and Storage Conditions

1998 ◽  
Vol 44 (3) ◽  
pp. 685-688 ◽  
Author(s):  
Klaus Jung ◽  
Philipp von Klinggräff ◽  
Brigitte Brux ◽  
Pranav Sinha ◽  
Dietmar Schnorr ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Storage Conditions ◽  
Blood Collection ◽  
And Storage

Stability of serum prostate-specific antigen determination across laboratory, assay, and storage time

Urology ◽  
1995 ◽  
Vol 45 (3) ◽  
pp. 447-453 ◽  
Author(s):  
Steven J. Jacobsen ◽  
George G. Klee ◽  
Hans Lilja ◽  
George L. Wright ◽  
Joseph E. Oesterling
Keyword(s):  
Prostate Specific Antigen ◽  
Storage Time ◽  
Specific Antigen ◽  
Serum Prostate Specific Antigen ◽  
Antigen Determination ◽  
And Storage ◽  
Laboratory Assay

Influences of specimen processing and storage conditions on results for plasma ammonia.

1984 ◽  
Vol 30 (6) ◽  
pp. 906-908 ◽  
Author(s):  
J H Howanitz ◽  
P J Howanitz ◽  
C A Skrodzki ◽  
J A Iwanski
Keyword(s):  
Whole Blood ◽  
Storage Conditions ◽  
Minimal Effect ◽  
Blood Components ◽  
Blood Storage ◽  
Specimen Handling ◽  
Plasma Ammonia ◽  
Specimen Processing ◽  
Processing And Storage ◽  
And Storage

Abstract Ammonia concentrations in plasma may increase because of contamination and deterioration of blood components during specimen handling and storage. Using replicate specimens from healthy volunteers, we studied influences of specimen processing and storage procedures on ammonia measurements made with a self-contained reagent system. Under some conditions, ammonia concentrations more than doubled. The use of nonhemolyzed plasma specimens and prompt centrifugation, separation of plasma, and ammonia determination apparently were important in avoiding such increases, the duration of contact between plasma and cells being the most important factor. Lower temperatures had minimal effect on whole-blood storage and centrifugation, but retarded increases in ammonia in stored plasma. We conclude that procedures for collection and storage of specimens for ammonia determinations should be standardized and strictly observed.

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