scholarly journals NMR SPECTROSCOPIC AND X-RAY STRUCTURAL CHARACTERIZATION OF TWO DIARYL DERIVATIVES OF (4-CYANO-6-METHYL-3,8-DIOXO-2,3,5,6,7,8-HEXAHYDROPYRIDO[3,4-c] ΡYRIDAZIN-6-YL)HYDRAZONO-ACETIC ACID ETHYL ESTER

2004 ◽  
Vol 10 (1) ◽  
Author(s):  
Katri Laihia ◽  
Erkki Kolehmainen ◽  
Elina Wegelius ◽  
Sergei Miltsov ◽  
Vladimir Nikiforov ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Ethyl Ester ◽  
Structural Characterization ◽  
Acid Ethyl Ester ◽  
X Ray ◽  
Derivatives Of

scholarly journals New Synthetic Routes for 1-Benzyl-1,4,7,10-tetraazacyclododecane and 1,4,7,10-Tetraazacyclododecane-1-acetic Acid Ethyl Ester, Important Starting Materials for Metal-coded DOTA-Based Affinity Tags

2007 ◽  
Vol 62 (3) ◽  
pp. 397-406 ◽  
Author(s):  
Stephan W. Kohl ◽  
Katharina Kuse ◽  
Markus Hummert ◽  
Herbert Schumann ◽  
Clemens Mügge ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Ethyl Ester ◽  
Nmr Spectra ◽  
Acid Ethyl Ester ◽  
Affinity Tags ◽  
X Ray ◽  
H Nmr ◽  
Synthetic Routes ◽  
New Compounds ◽  
C Nmr

Two improved routes to synthesize 1-benzyl-1,4,7,10-tetraazacyclododecane (6) and 1,4,7,10- tetraazacyclododecane-1-acetic acid ethyl ester (11) are described as well as the synthesis of 1-{2-[4-(maleimido-N-propylacetamidobutyl)amino]-2-oxoethyl}-1,4,7,10-tetraazacyclododecane- 4,7,10-triacetic acid (17) and its Y, Ho, Tm, and Lu complexes. The 1H and 13C NMR spectra of the new compounds as well as the single crystal X-ray structure analyses of the intermediates 4-benzyl-1,7-bis(p-toluenesulfonyl)diethylenetriamine (3) and 1,4,7-tris(p-toluenesulfonyl)diethylenetriamine (7) are reported and discussed. The rare earth complexes of 17 have been characterized by 1H NMR spectroscopy and MALDI-TOF mass spectrometry.

Synthesis and Characterization of Some New 2-Hydroxy-N-(3-Trifluoromethyl-Phenyl)-Benzamide Derivatives

2008 ◽  
Vol 59 (1) ◽  
pp. 56-60
Author(s):  
Ioana M.c. Ienascu ◽  
Alfa X. Lupea ◽  
Iuliana M. Popescu ◽  
Stefan Th. Tomas ◽  
Alina D. Zamfir
Keyword(s):  
Acetic Acid ◽  
Ethyl Ester ◽  
13C Nmr ◽  
Acid Ethyl Ester ◽  
Synthesis And Characterization ◽  
Chemical Methods ◽  
Physico Chemical ◽  
New Compounds ◽  
Benzamide Derivatives

In the reaction between 2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide and chloro-acetic acid ethyl ester, [2-(3-trifluoromethyl-phenylcarbamoyl)-phenoxy]-acetic acid ethyl ester was obtained. The ethyl ester was condensed with hydrazine giving 2-hydrazinocarbonylmethoxy-N-(3-trifluoromethyl-phenyl)-benzamide. This hydrazide is considered the key intermediate for the synthesis of new compounds. So, in the reaction between hydrazide and chloro-substituted benzaldehydes hydrazones were obtained. In order to establish their structures, all new synthesized compounds were analyzed by modern physico-chemical methods (FTIR, 1H-NMR, 13C-NMR, MS).

Synthesis and x-ray structural characterization of Cu(I) and Cu(II) derivatives of a new symmetric tripodal ligand N(CH2CH2-py)3, (py = 2-pyridyl)

1982 ◽  
Vol 64 ◽  
pp. L219-L220 ◽  
Author(s):  
Kenneth D. Karlin ◽  
Jon C. Hayes ◽  
John P. Hutchinson ◽  
Jeffrey R. Hyde ◽  
Jon Zubieta
Keyword(s):  
Structural Characterization ◽  
Tripodal Ligand ◽  
X Ray ◽  
Derivatives Of
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