Photocatalytic Oxidation of Pharmaceutical compounds: Kinetics and Pathways for Ibuprofen, Clofibric Acid, Diclofenac and Naproxen

2007 ◽  
Vol 10 (2) ◽  
Author(s):  
Haruthai Thanasawasdi ◽  
James Leckie ◽  
Theodore Mill
Keyword(s):  
Photocatalytic Oxidation ◽  
Pharmaceutical Compounds ◽  
Clofibric Acid

AbstractPhotocatalytic oxidation of ibuprofen, clofibric acid, diclofenac and naproxen were studied in near- UV illuminated (> 300nm) aqueous TiO

Photocatalytic Oxidation of Emerging Contaminants: Kinetics and Pathways for Photocatalytic Oxidation of Pharmaceutical Compounds

2006 ◽  
Vol 9 (1) ◽  
Author(s):  
Haruthai Tungudomwongsa ◽  
James Leckie ◽  
Theodore Mill
Keyword(s):  
Photocatalytic Oxidation ◽  
Emerging Contaminants ◽  
Pharmaceutical Compounds ◽  
Clofibric Acid

AbstractThe rates and products of photooxidation of ibuprofen, clofibric acid, diclofenac and naproxen, pharmaceuticals emerging as contaminants in wastewater, were examined in UV-irradiated TiO

EFFICIENT DEGRADATION OF CLOFIBRIC ACID BY HETEROGENEOUS PHOTOCATALYTIC OXIDATION PROCESS

2019 ◽  
Vol 18 (8) ◽  
pp. 1683-1692 ◽  
Author(s):  
Lidia Favier ◽  
Lacramioara Rusu ◽  
Andrei Ionut Simion ◽  
Raluca Maria Hlihor ◽  
Mariana Liliana Pacala ◽  
...  
Keyword(s):  
Photocatalytic Oxidation ◽  
Oxidation Process ◽  
Clofibric Acid

Mechanism considerations for photocatalytic oxidation, ozonation and photocatalytic ozonation of some pharmaceutical compounds in water

2013 ◽  
Vol 127 ◽  
pp. 114-124 ◽  
Author(s):  
Eva M. Rodríguez ◽  
Gracia Márquez ◽  
Elena A. León ◽  
Pedro M. Álvarez ◽  
Ana M. Amat ◽  
...  
Keyword(s):  
Photocatalytic Oxidation ◽  
Pharmaceutical Compounds ◽  
Photocatalytic Ozonation

A Practical and General Approach to the Late-Stage Functionalization of Complex Sulfonamides

2019 ◽  
Author(s):  
Patrick Fier ◽  
Kevin M. Maloney
Keyword(s):  
Functional Groups ◽  
Late Stage ◽  
Building Blocks ◽  
Pharmaceutical Compounds ◽  
Stage Conversion

Herein we describe the development and application of a method for the mild, late-stage conversion of primary sulfonamides to several other other functional groups. These reactions occur via initial reductive deamination of sulfonamides to sulfinates via an NHC-catalyzed reaction of transiently formed <i>N</i>-sulfonylimines. The method described here is tolerant of nearly all common functional groups, as exemplified by the late-stage derivatization of several complex pharmaceutical compounds. Based on the prevalence of sulfonamide-containing drugs and building blocks, we have developed a method to enable sulfonamides to be applied as versatile synthetic handles for synthetic chemsitry.

A Practical and General Approach to the Late-Stage Functionalization of Complex Sulfonamides

2019 ◽  
Author(s):  
Patrick Fier ◽  
Kevin M. Maloney
Keyword(s):  
Functional Groups ◽  
Late Stage ◽  
Building Blocks ◽  
Pharmaceutical Compounds ◽  
Stage Conversion

Herein we describe the development and application of a method for the mild, late-stage conversion of primary sulfonamides to several other other functional groups. These reactions occur via initial reductive deamination of sulfonamides to sulfinates via an NHC-catalyzed reaction of transiently formed <i>N</i>-sulfonylimines. The method described here is tolerant of nearly all common functional groups, as exemplified by the late-stage derivatization of several complex pharmaceutical compounds. Based on the prevalence of sulfonamide-containing drugs and building blocks, we have developed a method to enable sulfonamides to be applied as versatile synthetic handles for synthetic chemsitry.

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