HDlive Flow Silhouette with spatiotemporal image correlation for assessment of fetal cardiac structures at 12 to 14 + 6 weeks of gestation

Objectives To assess fetal cardiac structures using HDlive Flow Silhouette with spatiotemporal image correlation (STIC) at 12 to 14 + 6 weeks of gestation, and verify the feasibility of obtaining five cardiac views in the late first and early second trimesters of pregnancy. The fetal cardiac shape and the aspect of the descending aorta were also evaluated. Methods Eighty normal fetuses at 12 to 14 + 6 weeks of gestation were studied using trans-abdominal HDlive Flow Silhouette with STIC to assess the feasibility of five fetal cardiac views (frontal, spatial three-vessel, panoramic, posterior, and right lateral views). Target structures in each cardiac view were evaluated. ‘Good’ was assigned when all structures were noted, ‘Fair’ when only one structure was missed, and ‘Poor’ when two and more structures could not be detected. Frequencies of an elongated heart and those of a tortuous descending aorta were counted. Results Forty-nine fetuses were effectively included in the analysis. Success rates of ‘Good’ and ‘Fair’ were significantly higher with spatial three-vessel (p<0.01) and panoramic views (p<0.05). Frequencies of “Elongated heart”, “Elongated left ventricle”, and “Spherical heart” were 12.2, 6.2, and 81.6%, respectively. Frequencies of “Tortuous descending aorta” and “Straight descending aorta” were 12.2 and 87.8%, respectively. Conclusions The feasibility of obtaining fetal five cardiac views using HDlive Flow Silhouette with STIC is good, and this technique provides useful information for evaluating fetal cardiac structures in the late first and early second trimesters of pregnancy.