scholarly journals Role of FDG-PET scan in staging of pulmonary epithelioid hemangioendothelioma

Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 158-162 ◽  
Author(s):  
Cecilia Calabrese ◽  
Marina Gilli ◽  
Nicolina De Rosa ◽  
Vincenzo Di Crescenzo ◽  
Pio Zeppa ◽  
...  

AbstractIn this report we describe a case of pulmonary epithelioid hemangioendothelioma (PEH) in a young woman. The neoplasm manifested with dry cough, chest pain, finger clubbing, and multiple bilateral pulmonary nodules on chest x-ray and computed tomographic (CT) scan. She underwent thoracoscopy, and the histological features of the lung biopsies were initially interpreted as consistent with a not-well-defined interstitial lung disease. Our patient was clinically and radiologically stable over a period of four years, after which the disease progressed to involve not only the lung but also mediastinal lymph nodes, liver and bone. Fiberoptic bronchoscopy showed subtotal occlusion of the right middle and lower lobe bronchi. The histologic examination of bronchial biopsies revealed a poorly differentiated neoplasm immunohistochemically positive for vimentin and vascular markers CD31, CD34 and Factor VIII. A diagnosis of malignant hemangioendothelioma was made. Positron emission tomography (PET) is more sensitive than CT scan and bone scintigraphy in detecting PEH metastases. Furthermore, 18-fluorodeoxyglucose (FDG) uptake seems to be related to the grade of malignancy of PEH lesions. Therefore, we suggest that FDG-PET should be included in the staging system and follow-up of PEH.

Vascular ◽  
2005 ◽  
Vol 13 (4) ◽  
pp. 252-256 ◽  
Author(s):  
Shannon Lehner ◽  
Catherine Wittgen

Radiographic documentation of the rapid development of an aortic infection has not previously been reported. We report the case of a 68-year-old woman who presented with back pain. A computed tomographic(CT) scan documented a nondisplaced L1 compression fracture as well as an atherosclerotic but nonaneurysmal aorta. Two weeks after discharge, she developed left lower lobe pneumonia and was readmitted. A second CT scan was obtained because of continuous complaints of back pain. A contained rupture of the visceral aorta was now clearly visible. Emergent operation successfully repaired her aorta. The microorganisms responsible for aortic infection have changed since the widespread use of antibiotics. Patterns of aortic involvement have also evolved. The difficulty in making these diagnoses, the role of current antibiotic therapy, and the surgical options for these infections will be discussed.


2015 ◽  
Vol 26 (3) ◽  
pp. 279-280
Author(s):  
Mevlut Kurt ◽  
Emrah Posul ◽  
Guray Can ◽  
Bulent Yilmaz ◽  
Ugur Korkmaz ◽  
...  

2008 ◽  
Vol 22 (6) ◽  
pp. 521-524 ◽  
Author(s):  
Sadahiro Watanabe ◽  
Fuzuki Yano ◽  
Tamotsu Kita ◽  
Shigeyoshi Soga ◽  
Hiroshi Shinmoto ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Riccardo Cazzuffi ◽  
Nunzio Calia ◽  
Franco Ravenna ◽  
Claudio Pasquini ◽  
Sara Saturni ◽  
...  

We report here a case of primary pulmonary epithelioid hemangioendothelioma diagnosed in a 67-year-old Caucasian man, presenting with exertion dyspnoea, dry cough, and multiple bilateral pulmonary nodules revealed by computed tomography. At the 18F-fluorodeoxyglucose positron emission tomography, these nodules were negative. The histopathological diagnosis was made on a pulmonary wedge resection (performed during video-thoracoscopic surgery).


2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Romeu Duarte Mesquita ◽  
Marta Sousa ◽  
Carmen Trinidad ◽  
Eugénia Pinto ◽  
Iosu Antón Badiola

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining. Although the prognostic factors for PEH have not yet been well established, a better prognosis is usually associated with the multinodular pattern. We report two different imagological presentations of this rare disease, based on two institutional experiences, along with a review of the relevant literature.


2009 ◽  
Vol 50 (4) ◽  
pp. 374-378 ◽  
Author(s):  
Chung-Jen Huang ◽  
Dong-Ling You ◽  
Pei-Ing Lee ◽  
Li-Han Hsu ◽  
Chia-Chuan Liu ◽  
...  

Background: Pulmonary cryptococcosis is an uncommon cause of pulmonary nodules found by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scans. It is rarely reported but may mislead interpretation. Purpose: To describe the 18F-FDG PET/CT findings of pulmonary cryptococcosis. Material and Methods: The 18F-FDG PET/CT images of seven patients with pulmonary cryptococcosis were evaluated. Results: The 18F-FDG PET/CT exams showed single or multiple nodular lesions. The standardized uptake values (SUV) in early images varied significantly for the seven patients (ranging from 2.2 to 11.6). Delayed SUVs showed significant increases in four patients. Conclusion: Pulmonary cryptococcosis mimics primary or metastatic lung cancer on 18F-FDG PET/CT scan. Tissue confirmation should be considered for any suspicious pulmonary nodules found on 18F-FDG PET/CT scan with an SUV score higher than 2.5, in order to avoid overdiagnosis or overstaging.


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