scholarly journals New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Romeu Duarte Mesquita ◽  
Marta Sousa ◽  
Carmen Trinidad ◽  
Eugénia Pinto ◽  
Iosu Antón Badiola

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining. Although the prognostic factors for PEH have not yet been well established, a better prognosis is usually associated with the multinodular pattern. We report two different imagological presentations of this rare disease, based on two institutional experiences, along with a review of the relevant literature.

2006 ◽  
Vol 82 (6) ◽  
pp. 2010-2013 ◽  
Author(s):  
Patrick Bagan ◽  
Mohammed Hassan ◽  
Françoise Le Pimpec Barthes ◽  
Séverine Peyrard ◽  
Redha Souilamas ◽  
...  

Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 158-162 ◽  
Author(s):  
Cecilia Calabrese ◽  
Marina Gilli ◽  
Nicolina De Rosa ◽  
Vincenzo Di Crescenzo ◽  
Pio Zeppa ◽  
...  

AbstractIn this report we describe a case of pulmonary epithelioid hemangioendothelioma (PEH) in a young woman. The neoplasm manifested with dry cough, chest pain, finger clubbing, and multiple bilateral pulmonary nodules on chest x-ray and computed tomographic (CT) scan. She underwent thoracoscopy, and the histological features of the lung biopsies were initially interpreted as consistent with a not-well-defined interstitial lung disease. Our patient was clinically and radiologically stable over a period of four years, after which the disease progressed to involve not only the lung but also mediastinal lymph nodes, liver and bone. Fiberoptic bronchoscopy showed subtotal occlusion of the right middle and lower lobe bronchi. The histologic examination of bronchial biopsies revealed a poorly differentiated neoplasm immunohistochemically positive for vimentin and vascular markers CD31, CD34 and Factor VIII. A diagnosis of malignant hemangioendothelioma was made. Positron emission tomography (PET) is more sensitive than CT scan and bone scintigraphy in detecting PEH metastases. Furthermore, 18-fluorodeoxyglucose (FDG) uptake seems to be related to the grade of malignancy of PEH lesions. Therefore, we suggest that FDG-PET should be included in the staging system and follow-up of PEH.


2018 ◽  
Vol 5 (1) ◽  
pp. 65-68
Author(s):  
Nilufer Alpay Kanitez ◽  
Selda Celik ◽  
Sibel Yilmaz Oner ◽  
Halide Nur Urer ◽  
Cemal Bes ◽  
...  

CNS Spectrums ◽  
1997 ◽  
Vol 2 (5) ◽  
pp. 43-60 ◽  
Author(s):  
Bonnie R. Aronowitz ◽  
Concetta Decaria ◽  
Andrea Allen ◽  
Nicola Weiss ◽  
Audrey Saunders ◽  
...  

AbstractThe literature on neuropsychiatric, neuropsychological, and neuroimaging findings in autism and Asperger's disorder is briefly reviewed. Neurological soft sign, neuropsychological, and positron-emission tomography findings in one patient with Asperger's disorder and one patient with autism are highlighted, discussed as examples of heterogeneity, and integrated with the relevant literature.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Thu Thu Aung ◽  
Andrew Chu ◽  
Divya Kondapi ◽  
Danny Markabawi ◽  
Kanish Mirchia ◽  
...  

Pulmonary epithelioid hemangioendothelioma is a rare vascular tumor and infrequently described in medical literature as case reports and case series. Diagnosis is often incidental with high index of histopathological suspicion from clinical pathologist. The pathological pattern is quite unique with distinct immunohistochemical stains. Up to this day, there is no established standard treatment owing to the scarcity of this tumor. In this case report, we describe a case of pulmonary epithelioid hemangioendothelioma unexpectedly diagnosed with transthoracic needle biopsy, along with a review of the current literature.


2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Riccardo Cazzuffi ◽  
Nunzio Calia ◽  
Franco Ravenna ◽  
Claudio Pasquini ◽  
Sara Saturni ◽  
...  

We report here a case of primary pulmonary epithelioid hemangioendothelioma diagnosed in a 67-year-old Caucasian man, presenting with exertion dyspnoea, dry cough, and multiple bilateral pulmonary nodules revealed by computed tomography. At the 18F-fluorodeoxyglucose positron emission tomography, these nodules were negative. The histopathological diagnosis was made on a pulmonary wedge resection (performed during video-thoracoscopic surgery).


Sign in / Sign up

Export Citation Format

Share Document