Key words: Titanium(IV), Hydrazone, Schiff Base, Molecular Structure, Cyclic Voltammetry

2009 ◽  
Vol 64 (4) ◽  
pp. 415-422 ◽  
Author(s):  
Elsayed M. Afsah ◽  
Ahmed A. Fadda ◽  
Samir Bondock ◽  
Mohamed M. Hammouda
Keyword(s):  
Molecular Structure ◽  
Cyclic Voltammetry ◽  
Schiff Base ◽  
Mannich Reaction ◽  
Periodate Oxidation ◽  
Aromatic Aldehydes ◽  
Schmidt Reaction ◽  
Formaldehyde Oxidation ◽  
The Mannich Reaction ◽  
Methylene Derivative

Tetrahydro-1H-benzo[b]azonin-2,7-dione (2a) has been used as a precursor in the synthesis of dibenzo[ b,f ][1,5]diazacyclododecene and dibenzo[b,g][1,6]diazacyclododecene ring systems 4 and 5, respectively, via periodate oxidation of the appropriate indolo-benzo[b]azonines 3 and 7. The synthesis of hexahydro-benzo[b][1,4]diazecin-2,7-dione (10) has been achieved by the Schmidt reaction of 2a. The periodate oxidation of 9,9´-methylenebis(2,3,4,9-tetrahydro-1H-carbazole) (11) afforded 1,1´- methylenebis(3,4,5,6-tetrahydro-1H-benzo[b]azonin-2,7-dione) (12). Its 6,6´-methylenebis isomer 13 was obtained by treating 2a with formaldehyde. Oxidation of 16 gave the unsymmetrical bi(benzo [b]azonine) 17.The Mannich reaction of 2a led to a mixture of its 6-methylene derivative 19 and the spirocyclic system 20. The reactions of 2a with aldimines and aromatic aldehydes were also investigated.

Synthesis and some reactions of functionalized 11,12-dihydro-5H-dibenzo[b,g]azonines

2015 ◽  
Vol 70 (6) ◽  
pp. 385-391 ◽  
Author(s):  
Elsayed M. Afsah ◽  
Ahmed A. Fadda ◽  
Samir Bondock ◽  
Mohamed M. Hammouda
Keyword(s):  
Mannich Reaction ◽  
Periodate Oxidation ◽  
Aromatic Aldehydes ◽  
Ring System ◽  
Schmidt Reaction ◽  
Ring Systems ◽  
Fischer Indolization ◽  
The Mannich Reaction ◽  
Polycyclic System

AbstractDihydro-5H-dibenzo[b,g]azonine-6,13-dione (2) has been used as a precursor in the synthesis of the indolo[2,3-e]dibenzo[b,g]azonine and tribenzo[b,g,j][1,6]diazacyclododecine ring systems 6 and 7 respectively via a Fischer indolization/periodate oxidation sequence. Fischer indolization of the (1,4-phenylenedihydrazono) derivative 8 gave the polycyclic system 9. The Schmidt reaction of 2 led to the formation of the benzimidazo[1,2-b] [2]benzazepine ring system 11. The Mannich reaction of 2 led to the spirocyclic system 15. The reactions of 2 with aldimines and aromatic aldehydes were also investigated.

The Mannich Reaction Between Aromatic Ketones, Aromatic Aldehydes and Aromatic Amines

Synthesis ◽  
1991 ◽  
Vol 1991 (09) ◽  
pp. 717-718 ◽  
Author(s):  
Yi Lin ◽  
Lei Huangshu ◽  
Zou Junhua ◽  
Xu Xiujuan
Keyword(s):  
Mannich Reaction ◽  
Aromatic Amines ◽  
Aromatic Aldehydes ◽  
Aromatic Ketones ◽  
The Mannich Reaction

Synthesis of some new hydrazide-hydrazones related to isatin and its Mannich and Schiff bases

2016 ◽  
Vol 71 (11) ◽  
pp. 1147-1157 ◽  
Author(s):  
Elsayed M. Afsah ◽  
Saad S. Elmorsy ◽  
Soha M. Abdelmageed ◽  
Zaki E. Zaki
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Mannich Reaction ◽  
Mannich Base ◽  
The Mannich Reaction

AbstractThe hydrazide-hydrazones 6a–d and 7a, b were obtained by treating isatin (1) or its Mannich base 2 with hydrazides incorporating piperidine, morpholine, and piperazine units. The reaction of 1 and 2 with hydrazides related to triazenes having piperidine, morpholine, and 1,2,3,4-tetrahydroisoquinoline moieties gave 12a–c and 13a–c. Treatment of 1 and 2 with iminodiacetohydrazide (14) and ethylenediamine tetraacetohydrazide (18) afforded 15–17 and 19a, b, respectively. The Mannich reaction of the Schiff base 20 with formaldehyde and the appropriate hydrazide or bis(hydrazide) gave 21a, b and 22a, b. The hydrazides related to Schiff bases 20 and 26 were used as precursors in synthesis of compounds incorporating two 2-oxoindoline units or formazan moiety.

One-pot three-component Mannich reaction in water catalyzed by eco-friendly, hydrophobic and recyclable sulfonic acid based nanosilica (SBA-15-Ph-PrSO3H)

RSC Advances ◽  
2014 ◽  
Vol 4 (71) ◽  
pp. 37941-37946 ◽  
Author(s):  
Daryoush Zareyee ◽  
Hamidreza Alizadeh
Keyword(s):  
Mannich Reaction ◽  
Aromatic Amines ◽  
Sulfonic Acid ◽  
Room Temperature ◽  
Aromatic Aldehydes ◽  
Green Method ◽  
One Pot ◽  
The Mannich Reaction ◽  
Reaction In Water

A mild, effective and green method for the Mannich reaction of aromatic aldehydes, aromatic amines and ketones has been accomplished in good to excellent yields using hydrophobic SBA-15-Ph-PrSO3H in water at room temperature.

THE MANNICH REACTION OF CYCLIC KETONES, AROMATIC ALDEHYDES AND AROMATIC AMINES

1991 ◽  
Vol 23 (5) ◽  
pp. 673-676 ◽  
Author(s):  
Yi Lin ◽  
Zou Junhua ◽  
Lei Huangshu ◽  
Lin Xiaomei ◽  
Zhang Mingxiao
Keyword(s):  
Mannich Reaction ◽  
Aromatic Amines ◽  
Aromatic Aldehydes ◽  
Cyclic Ketones ◽  
The Mannich Reaction

The Mannich Reaction of Butanone, Aromatic Aldehydes and Aromatic Amines

1991 ◽  
Vol 21 (20) ◽  
pp. 2109-2117 ◽  
Author(s):  
Yi Lin ◽  
Zou Junhua ◽  
Lei Huangshu ◽  
He Qilin
Keyword(s):  
Mannich Reaction ◽  
Aromatic Amines ◽  
Aromatic Aldehydes ◽  
The Mannich Reaction
Sign in / Sign up

Export Citation Format

Share Document