Molecular Dynamics Simulations of NAD+-Induced Domain Closure in Horse Liver Alcohol Dehydrogenase

Biophysical Journal ◽

10.1529/biophysj.106.085910 ◽

2006 ◽

Vol 91 (5) ◽

pp. 1823-1831 ◽

Author(s):

Steven Hayward ◽

Akio Kitao

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Molecular Dynamics Simulations ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Dynamics Simulations

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Dynamic Structures of Horse Liver Alcohol Dehydrogenase (HLADH): Results of Molecular Dynamics Simulations of HLADH-NAD+-PhCH2OH, HLADH-NAD+-PhCH2O-, and HLADH-NADH-PhCHO

Journal of the American Chemical Society ◽

10.1021/ja0109747 ◽

2001 ◽

Vol 123 (48) ◽

pp. 11952-11959 ◽

Author(s):

Jia Luo ◽

Thomas C. Bruice

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Molecular Dynamics Simulations ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Dynamic Structures ◽

Dynamics Simulations

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Response to Comment on “Effect of Active Site Mutation Phe93 → Trp in the Horse Liver Alcohol Dehydrogenase Enzyme on Catalysis: A Molecular Dynamics Study”

The Journal of Physical Chemistry B ◽

10.1021/jp035474+ ◽

2003 ◽

Vol 107 (44) ◽

pp. 12372-12372 ◽

Author(s):

Steven D. Schwartz

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Site Mutation ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Dehydrogenase Enzyme

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Comment on “Effect of Active Site Mutation Phe93 → Trp in the Horse Liver Alcohol Dehydrogenase Enzyme on Catalysis: A Molecular Dynamics Study”

The Journal of Physical Chemistry B ◽

10.1021/jp034932b ◽

2003 ◽

Vol 107 (44) ◽

pp. 12370-12371 ◽

Author(s):

Arieh Warshel ◽

Jordi Villà-Freixa

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Site Mutation ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Dehydrogenase Enzyme

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Effect of Active Site Mutation Phe 93 → Trp in the Horse Liver Alcohol Dehydrogenase Enzyme on Catalysis: A Molecular Dynamics Study

The Journal of Physical Chemistry B ◽

10.1021/jp027088i ◽

2002 ◽

Vol 106 (51) ◽

pp. 13111-13113 ◽

Author(s):

C. Kalyanaraman ◽

Steven D. Schwartz

Keyword(s):

Molecular Dynamics ◽

Alcohol Dehydrogenase ◽

Active Site ◽

Site Mutation ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

Horse Liver ◽

Dehydrogenase Enzyme

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Ten-nanosecond molecular dynamics simulation of the motions of the horse liver alcohol dehydrogenase*PhCH2O- complex

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.262667599 ◽

2002 ◽

Vol 99 (26) ◽

pp. 16597-16600 ◽

Author(s):

J. Luo ◽

T. C. Bruice

Keyword(s):

Molecular Dynamics ◽

Molecular Dynamics Simulation ◽

Alcohol Dehydrogenase ◽

Dynamics Simulation ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

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Chloroprothixene binding into the active site pocket of horse liver alcohol dehydrogenase

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19760928 ◽

1976 ◽

Vol 41 (3) ◽

pp. 928-940 ◽

Author(s):

J. Kovář ◽

L. Skurský ◽

K. Bláha

Keyword(s):

Alcohol Dehydrogenase ◽

Active Site ◽

Horse Liver Alcohol Dehydrogenase ◽

Active Site Pocket ◽

Liver Alcohol Dehydrogenase ◽

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Binding of substrate in a ternary complex of horse liver alcohol dehydrogenase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)45387-8 ◽

1982 ◽

Vol 257 (23) ◽

pp. 14349-14358 ◽

Author(s):

H Eklund ◽

B V Plapp ◽

J P Samama ◽

C I Brändén

Keyword(s):

Alcohol Dehydrogenase ◽

Ternary Complex ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

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Activation and inactivation of horse liver alcohol dehydrogenase with pyridoxal compounds.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)42001-2 ◽

1975 ◽

Vol 250 (1) ◽

pp. 205-210

Author(s):

D C Sogin ◽

B V Plapp

Keyword(s):

Alcohol Dehydrogenase ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

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The Behavior of Horse Liver Alcohol Dehydrogenase in Guanidine Hydrochloride Solutions

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)94306-1 ◽

1969 ◽

Vol 244 (18) ◽

pp. 5034-5043

Author(s):

R W Green ◽

R H McKay

Keyword(s):

Alcohol Dehydrogenase ◽

Guanidine Hydrochloride ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

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Rate constants for a mechanism including intermediates in the interconversion of ternary complexes by horse liver alcohol dehydrogenase

Biochemistry ◽

10.1021/bi00470a005 ◽

1990 ◽

Vol 29 (18) ◽

pp. 4289-4295 ◽

Author(s):

V. Chandra Sekhar ◽

Bryce V. Plapp

Keyword(s):

Alcohol Dehydrogenase ◽

Rate Constants ◽

Ternary Complexes ◽

Horse Liver Alcohol Dehydrogenase ◽

Liver Alcohol Dehydrogenase ◽

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