THE INFLUENCE OF DEXAMETHASONE ON THE CARBOHYDRATE METABOLISM OF THE ADRENAL CORTEX OF THE RAT

Donor twins in the monovular placental transfusion syndrome have organs which are significantly different than those found in their better nourished recipient partners. The malnourished donors have disproportionate reductions in the size of liver, pancreas, and fetal adrenal cortex. Liver and adrenal abnormalities are due to a reduced mass of cytoplasm of individual parenchymal cells. The mass of pancreatic islet tissue was as great as that found in well nourished neonates of the same gestational age. All of these anatomic changes have possible implications for neonatal carbohydrate metabolism.

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THE RELATION OF THE ADRENAL CORTEX TO CARBOHYDRATE METABOLISM

American Journal of Physiology-Legacy Content ◽

10.1152/ajplegacy.1938.122.2.460 ◽

1938 ◽

Vol 122 (2) ◽

pp. 460-471 ◽

Cited By ~ 7

Author(s):

Arthur Grollman

Keyword(s):

Carbohydrate Metabolism ◽

Adrenal Cortex

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Pork Adrenal-Cortex Extract: Effect upon Carbohydrate Metabolism and Work Capacity in Addison's Disease1

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem-4-7-287 ◽

1944 ◽

Vol 4 (7) ◽

pp. 287-296 ◽

Cited By ~ 8

Author(s):

Cyril M. Macbryde ◽

F. A. De La Balze

Keyword(s):

Carbohydrate Metabolism ◽

Adrenal Cortex ◽

Work Capacity

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HYPOPHYSEO-ADRENAL FUNCTION IN DIABETIC ANGIOPATHY

Acta Endocrinologica ◽

10.1530/acta.0.0460135 ◽

1964 ◽

Vol 46 (1) ◽

pp. 135-141 ◽

Cited By ~ 5

Author(s):

S. Szücs ◽

G. Csapó

Keyword(s):

Carbohydrate Metabolism ◽

Adrenal Cortex ◽

Cortisol Level ◽

Plasma Cortisol ◽

Plasma Cortisol Level ◽

Adrenal Function ◽

Diabetic Patients ◽

Diabetic Angiopathy ◽

Hormone Production

ABSTRACT It has been demonstrated that alterations in the corticotrophin-glucocorticoid system follow the extreme changes in carbohydrate metabolism which occur in diabetic patients. In acidosis and hypoglycaemia there is a transitory pathological increase in the plasma cortisol level and in the urinary 17-OHCS excretion. If the diabetes is satisfactorily controlled – even in labile patients – the average values are normal. In satisfactorily controlled angiopathic patients a pathologically increased hormone production cannot be demonstrated. In the uraemic phase of the Kimmelstiel-Wilson syndrome the function of the adrenal cortex deteriorates.

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