Retrospective audit of the use of cinacalcet for the treatment of primary hyperparathyroidism in adults against the NHS England prescribing criteria

2017 ◽  
Author(s):  
Andrew Ghabbour ◽  
Shakeel Ahmed ◽  
Anna Crown
2018 ◽  
Vol 12 (4) ◽  
pp. 175-179 ◽  
Author(s):  
Jessica Gehlert ◽  
Adam Morton

Introduction Asymptomatic mild primary hyperparathyroidism is increasingly being identified during pregnancy. Recent studies have demonstrated inconsistent findings with regard to pregnancy complications and the need for surgical intervention during pregnancy. Method A retrospective audit of outcomes of pregnancies complicated by hypercalcaemia over a 15-year period was performed. Results Twenty-nine pregnancies to 26 women with hypercalcaemia were identified, corresponding to 37 cases per 100,000 deliveries. Hypercalcaemia was due to primary hyperparathyroidism in 90% of cases, with mean serum calcium of 2.89 mmol/l and mean ionised calcium 1.43 mmol/l. Four women underwent successful neck exploration during pregnancy. Pregnancy complications were limited to three cases of pre-eclampsia and one case of symptomatic neonatal hypoparathyroidism. Conclusion Close observation without surgical intervention would seem reasonable in women with mild hypercalcaemia during pregnancy.


2005 ◽  
Vol 38 (23) ◽  
pp. 19
Author(s):  
WILLIAM E. GOLDEN ◽  
ROBERT H. HOPKINS

2015 ◽  
Vol 21 ◽  
pp. 142-143
Author(s):  
Sailesh Lodha ◽  
Deependra N Singh ◽  
Ankur Gahlot

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