Hypoplastic coronary artery disease and hypertension in a child: a case report

Background Hypoplastic coronary artery disease (HCAD) is an extremely rare disease associated with a risk of sudden cardiac death. It is rarely recognized in a live pediatric patient. Case summary We report a case of HCAD in a patient who first presented with vomiting and poor feeding, suggestive of acute heart failure due to cardiomyopathy or acute myocarditis in infancy. Hypertension and signs of ischemia became evident on electrocardiography and scintigraphy after his cardiac function fully recovered, and he was diagnosed with HCAD by angiography performed at the age of eight years. He has remained under close observation with anti-hypertensives, aspirin, and exercise restriction. Discussion Although HCAD is a rare disease, it may not only cause ischemia but may also result in heart failure and sudden cardiac death. It should be considered in any pediatric patient with heart failure. Mid-term follow-up visits might be necessary to detect signs of ischemia in pediatric patients presenting with features of heart failure.

Employees’ Post-service Plans and Options in Nigeria

One of the greatest challenges that faced typical employees throughout their working life is life after retirement. Despite government roles at providing social security, retirement epoch has been a tension provoking and overwhelming phenomenon in Nigeria and other emerging economies of Africa, Asia and Latin America. A close observation of many retirees in Nigeria society and the problems they are facing draw the attention of all and sundry. These problems seem to range from sudden death, dwindling status, lack of occupation, loss of the usual monthly salary, decreased strength and deteriorated health condition, physical disabilities, aging and anxiety about a residential home. In Nigeria, the regular non-payment of pensions and gratuities benefits has brought untold hardship and sudden death to many retirees, thereby making retirement something that is dreaded by workers. This problem is further compounded to lack of planning and management of post-service epoch and conditions. It is against this backdrop that this paper seeks to identify and discusses strategies available for managing post-service condition in Nigeria. The paper calls on Nigerian workers to embrace one of the options to remain moderately productive and healthy after retirement. The paper suggests, among others, that both employers and government should undertake regular pre-retirement training for their workers in order to save the country the embarrassment of seeing their retirees going to early graves or turning into destitute on the streets.

Treatable Ataxia: a comprehensive case series study

Autosomal recessive cerebellar ataxias are a group of heterogeneous early-onset progressive disorders that some of them are treatable. We performed 4-year-follow up for 25 patients that considered as treatable ataxia in the literature. According to our study, patients would benefit from early detection of treatable ataxia, close observation, and follow-up.

The CO2 Emission Efficiency of China’s Hotel Industry under the Double Carbon Objectives and Homestay Growth

Hotels emit large amounts of CO2 when providing services. Carbon neutrality objectives and the growth of homestays have forced hotel managers to pay more attention to carbon reduction. First, this paper adopted the input–output method to calculate hotel CO2 emissions. It was found that the amount of CO2 emissions in the hotel industry decreased from the year of 2016 to 2018, and there are structural differences in the CO2 emissions of the hotel industry in China. Furthermore, this paper adopted the three-stage SBM-DEA model to evaluate hotel CO2 emission efficiency in 30 provinces in China. The results show that CO2 emission efficiency increased significantly when environmental factors were eliminated. A close observation of different regions shows that the eastern region has a higher CO2 emission efficiency than the western and middle regions. The emergence of homestays has led to increased input slacks in the labor and energy consumption of hotels, which has a negative effect on efficiency indirectly. Finally, implications and recommendations for the hotel industry are proposed.

Labour in Wonder Woman: A Marxist Feminist Reading

An Amazonian Goddess who was raised a warrior set in World War I, screams the impact of Marxism. Wonder Women (2017), produced by DC, has a nominal heroine who seems like an icon of Feminism but is instead the opposite in close observation. Though the character seems vigorously empowered, she is reduced to a commodity in the clutches of capitalism. Wonder Woman’s labour was tried to fit into the domestic sphere. This paper would explore the film from the focal lenses of Marxist Feminism. The investigative questions revolve around ‘cheap labour,’ ‘reserve labour,’ and ‘reproduction.’ Also, the marginalized status of other proletariats is examined. How the character becomes a target of capitalism by pushing her into the domestic sphere and objectification is the paper’s primary concern. The paper would use a qualitative approach to achieve the desired result. The analysis will be a subjective judgment based on the film text. The characters’ cognitive behavior and the surrounding are a central element that will be explored through the narrative analysis. The research methodology will employ conceptualization and qualitative design and methodology.

NILAI MORAL TOKOH UTAMA DALAM “LEGENDA MALIN KUNDANG” DAN “SI TENGGANG”: KAJIAN SASTRA BANDINGAN SERTA IMPLEMENTASINYA SEBAGAI BAHAN AJAR SASTRA DI SMA

ABSTRAK Penelitian ini bertujuan untuk menemukan perbandingan nilai moral tokoh utama dalam “Legenda Malin Kundang” dan “Si Tenggang” serta implementasinya sebagai bahan ajar sastra di SMA. Penelitian ini menggunakan kajian sastra bandingan. Pengumpulan data dilakukan dengan metode simak dengan teknik dasar sadap catat. Metode analisis data menggunakan metode padan dengan teknik dasar Pilah Unsur Penentu (PUP). Hasil penelitian ini menunjukkan adanya tiga jenis nilai moral dalam “Legenda Malin Kundang” dan “Si Tenggang” yang meliputi (1) moralitas hubungan manusia dengan diri sendiri, (2) moralitas hubungan manusia dengan lingkungan sosial termasuk hubungannya dengan lingkungan alam, dan (3) moralitas hubungan manusia dengan Tuhan. Selanjutnya hasil penelitian ini akan diimplementasikan dalam bentuk handout untuk siswa SMA.Kata Kunci: legenda, nilai moral, sastra bandingan ABSTRACTThis study aims to compare moral values brought by the main characters of Legenda Malin Kundang and Si Tenggang and the implementation of those values as literature teaching materials in high school. This research applies comparative literature study method. The data are collected by data collection methods a close observation and deep listening with a basic technique of taking some notes. The data analysis method applies an identity method with taking advantages of a basic technique, sorting determinants of elements (PUP). The results of this study reveal that there are three types of moral values in Legenda Malin Kundang and Si Tenggang, covering (1) morality of human relations with oneself, (2) morality of human relations with the social environment including their relationship with natural environment, and (3) morality of human relations with the God. Finally, the results of this study are implemented in the form of handouts for high school students.Keywords: legend, moral value, comparative literatur

Increasing Animal Cognition Research in Zoos

Animal cognition covers various mental processes including perception, learning, decision-making and memory, and animal behavior is often used as a proxy for measuring cognition. Animal cognition/behavior research has multiple benefits; it provides fundamental knowledge on animal biology and evolution but can also have applied conservation and welfare applications. Zoos provide an excellent yet relatively untapped resource for animal cognition research, because they house a wide variety of species - many of which are under threat - and allow close observation and relatively high experimental control compared to the wild. Multi-zoo collaboration leads to increased sample size and species representation, which in turn leads to more robust science. However, there are salient challenges associated with zoo-based cognitive research, which are subject-based (e.g., small sample sizes at single zoos, untrained/unhabituated subjects, site effects) and human-based (e.g., time restrictions, safety concerns, and perceptions of animals interacting with unnatural technology or apparatus). We aim to increase the understanding and subsequent uptake of animal cognition research in zoos, by transparently outlining the main benefits and challenges. Importantly, we use our own research (1) a study on novelty responses in hornbills, and (2) a multi-zoo collaboration called the ManyBirds project to demonstrate how challenges may be overcome. These potential options include using drop and go apparatuses that require no training, close human contact or animal separation. This article is aimed at zoo animal care and research staff, as well as external researchers interested in zoo-based studies.

Risk Factors Associated with Refractory Epilepsy in Patients with Tuberous Sclerosis Complex: A Systematic Review

Background: Epilepsy affects 70–90% of patients with tuberous sclerosis complex (TSC). In one-third of them, the seizures become refractory to treatment. Drug-resistant epilepsy (DRE) carries a significant educational, social, cognitive, and economic burden. Therefore, determining risk factors that increase the odds of refractory seizures is needed. We reviewed current data on risk factors associated with DRE in patients with tuberous sclerosis. Methods: The review was performed according to the PRISMA guidelines. Embase, Cochrane Library, MEDLINE, and ClinicalTrial.gov databases were searched. Only full-text journal articles on patients with TSC which defined risk factors related to DRE were included. Results: Twenty articles were identified, with a cohort size between 6 and 1546. Seven studies were prospective. Three factors appear to significantly increase DRE risk: TSC2 mutation, infantile spasms, and a high number of cortical tubers. Conclusions: A proper MRI and EEG monitoring, along with genetic testing, and close observation of individuals with early onset of seizures, allow identification of the patients at risk of DRE.

Study of potential games using Ising interaction

Problems can be handled properly in game theory as long as a countable number of players are considered, whereas, in real life, we have a large number of players. Hence, games at the thermodynamic limit are analyzed in general. There is a one-to-one correspondence between classical games and the modeled Hamiltonian at a particular equilibrium condition, usually the Nash equilibrium. Such a correspondence is arrived for symmetric games, namely the Prisoner’s Dilemma using the Ising Hamiltonian. In this work, we have shown that another class of games known as potential games can be analyzed with the Ising Hamiltonian. Analysis of this work brings out very close observation with real-world scenarios. In other words, the model of a potential game studied using Ising Hamiltonian predicts behavioral aspects of a large population precisely.

Stevens-Johnson Syndrome Caused by Enzalutamide: A Case Report and Literature Review

ObjectiveEnzalutamide is the most frequently prescribed compound for treating metastatic castration-resistant prostate cancer (mCRPC). Common adverse drug events of enzalutamide are febrile neutropenia, hot flashes, hypertension, and fatigue.MethodsWe present a case of a patient with mCRPC who received enzalutamide and developed Stevens-Johnson syndrome (SJS). The culprit drug was confirmed using the Naranjo Adverse Drug Reaction Probability Scale. Clinical characteristics and management principles were analyzed in combination with literature reports.ResultsSJS occurred within two weeks of enzalutamide therapy. Supportive care such as steroid treatment led to a complete resolution of skin lesions and improved clinical symptoms after three weeks.ConclusionMost cutaneous adverse events occur early during enzalutamide therapy, and close observation should be given within two weeks of starting treatment.