Splicing machinery landscape is dysregulated in chronic liver disease: central role of EIF4A3 in hepatocarcinogenesis.

2021 ◽  
Author(s):  
Juan Luis López-Cánovas ◽  
Natalia Hermán-Sánchez ◽  
María T Moreno-Montilla ◽  
Rio-Moreno Mercedes del ◽  
Marina E. Sánchez-Frias ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Splicing Machinery

scholarly journals The Role of Iron and Iron Overload in Chronic Liver Disease

2016 ◽  
Vol 22 ◽  
pp. 2144-2151 ◽  
Author(s):  
Sandra Milic ◽  
Ivana Mikolasevic ◽  
Lidija Orlic ◽  
Edita Devcic ◽  
Nada Starcevic-Cizmarevic ◽  
...  
Keyword(s):  
Liver Disease ◽  
Iron Overload ◽  
Chronic Liver Disease ◽  
Chronic Liver

scholarly journals The Matrisome, Inflammation, and Liver Disease

2020 ◽  
Vol 40 (02) ◽  
pp. 180-188 ◽  
Author(s):  
Christine E. Dolin ◽  
Gavin E. Arteel
Keyword(s):  
Extracellular Matrix ◽  
Liver Disease ◽  
Fatty Liver ◽  
Chronic Liver Disease ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Disease Development ◽  
Disease States ◽  
Ecm Proteins

AbstractChronic fatty liver disease is common worldwide. This disease is a spectrum of disease states, ranging from simple steatosis (fat accumulation) to inflammation, and eventually to fibrosis and cirrhosis if untreated. The fibrotic stage of chronic liver disease is primarily characterized by robust accumulation of extracellular matrix (ECM) proteins (collagens) that ultimately impairs the function of the organ. The role of the ECM in early stages of chronic liver disease is less well-understood, but recent research has demonstrated that several changes in the hepatic ECM in prefibrotic liver disease are not only present but may also contribute to disease progression. The purpose of this review is to summarize the established and proposed changes to the hepatic ECM that may contribute to inflammation during earlier stages of disease development, and to discuss potential mechanisms by which these changes may mediate the progression of the disease.

Chronic liver disease in central harlem: The role of alcohol and viral hepatitis

Hepatology ◽  
1999 ◽  
Vol 29 (3) ◽  
pp. 883-888 ◽  
Author(s):  
Thomas R. Frieden ◽  
Lisa Ozick ◽  
Colin McCord ◽  
Omana V. Nainan ◽  
Sara Workman ◽  
...  
Keyword(s):  
Liver Disease ◽  
Viral Hepatitis ◽  
Chronic Liver Disease ◽  
Chronic Liver

The role of liver and spleen elastography in advanced chronic liver disease

2021 ◽  
Vol 67 (2) ◽  
Author(s):  
Elton DAJTI ◽  
Giovanni MARASCO ◽  
Federico RAVAIOLI ◽  
Luigina V. ALEMANNI ◽  
Benedetta ROSSINI ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver

scholarly journals Sequential Occurrence of Hepatocellular Carcinoma Following Waldenstroem's Macroglobulinemia: The Pathogenetic Role of Chronic Liver Disease.

1996 ◽  
Vol 35 (5) ◽  
pp. 416-418 ◽  
Author(s):  
Tohru IZUMI ◽  
Ryuhei SASAKI ◽  
Saburo TSUNODA ◽  
Makio HATAKEYAMA ◽  
Hirotaka KOYAMA ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Pathogenetic Role
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