Intestinal Organoids as Vehicles for Therapeutic Peptide Delivery

2021 ◽  
Author(s):  
Yuxian Lei ◽  
Gavin Bewick
Keyword(s):  
Peptide Delivery ◽  
Therapeutic Peptide ◽  
Intestinal Organoids

scholarly journals MMP9-sensitive polymers mediate environmentally-responsive bivalirudin release and thrombin inhibition

2015 ◽  
Vol 3 (1) ◽  
pp. 41-45 ◽  
Author(s):  
D. S. Chu ◽  
D. L. Sellers ◽  
M. J. Bocek ◽  
A. E. Fischedick ◽  
P. J. Horner ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injuries ◽  
Peptide Delivery ◽  
Therapeutic Peptide ◽  
Thrombin Inhibition ◽  
Injured Tissue ◽  
Environmentally Responsive ◽  
Thermoresponsive Hydrogels

Enzymatically-responsive bivalirudin polymers loaded in thermoresponsive hydrogels mediate localized therapeutic peptide delivery in spinal cord injuries. These materials respond to upregulated remodelling enzymes to release therapeutic peptide into injured tissue.

scholarly journals Physicochemical and Formulation Developability Assessment for Therapeutic Peptide Delivery—A Primer

2014 ◽  
Vol 17 (1) ◽  
pp. 144-155 ◽  
Author(s):  
Annette Bak ◽  
Dennis Leung ◽  
Stephanie E. Barrett ◽  
Seth Forster ◽  
Ellen C. Minnihan ◽  
...  
Keyword(s):  
Peptide Delivery ◽  
Therapeutic Peptide

Molecular engineering solutions for therapeutic peptide delivery

2017 ◽  
Vol 46 (21) ◽  
pp. 6553-6569 ◽  
Author(s):  
Handan Acar ◽  
Jeffrey M. Ting ◽  
Samanvaya Srivastava ◽  
James L. LaBelle ◽  
Matthew V. Tirrell
Keyword(s):  
Peptide Delivery ◽  
Molecular Engineering ◽  
The Body ◽  
Therapeutic Peptide ◽  
Therapeutic Peptides ◽  
Self Assembled

This review discusses self-assembled vehicles as nanoparticles to carry and protect therapeutic peptides through their journeys in the body.

Orally Administered Therapeutic Peptide Delivery: Enhanced Absorption Through the Small Intestine Using Permeation Enhancers

2012 ◽  
Vol 18 (3) ◽  
pp. 259-280 ◽  
Author(s):  
Viness Pillay ◽  
Angus R. Hibbins ◽  
Yahya E. Choonara ◽  
Lisa C. du Toit ◽  
Pradeep Kumar ◽  
...  
Keyword(s):  
Small Intestine ◽  
Peptide Delivery ◽  
Permeation Enhancers ◽  
Therapeutic Peptide ◽  
Enhanced Absorption

Polymer-based vehicles for therapeutic peptide delivery

2015 ◽  
Vol 6 (11) ◽  
pp. 1279-1296 ◽  
Author(s):  
Jinjin Zhang ◽  
Swapnil S Desale ◽  
Tatiana K Bronich
Keyword(s):  
Peptide Delivery ◽  
Therapeutic Peptide

Therapeutic peptide delivery via aptamer-displaying, disulfide-linked peptide amphiphile micelles

2020 ◽  
Vol 5 (1) ◽  
pp. 269-283
Author(s):  
Josiah D. Smith ◽  
Leah N. Cardwell ◽  
David Porciani ◽  
Andrea Nolla ◽  
Brenna T. Cornelison ◽  
...  
Keyword(s):  
Peptide Delivery ◽  
Peptide Amphiphile ◽  
Therapeutic Peptide ◽  
Platform Technology

Peptide amphiphile micelles (PAMs) are a powerful platform technology for improving the delivery of therapeutic and prophylactic peptides.

Challenges and new strategies for therapeutic peptide delivery to the CNS

2015 ◽  
Vol 6 (7) ◽  
pp. 841-853 ◽  
Author(s):  
Jeremy WD McGowan ◽  
Gene L Bidwell ◽  
Parminder JS Vig
Keyword(s):  
Peptide Delivery ◽  
Therapeutic Peptide ◽  
New Strategies

Targeted Therapeutic Peptide Delivery to Synaptic Junctions as Botulism Countermeasure

2007 ◽  
Vol 21 (6) ◽  
Author(s):  
Peng Zhang ◽  
Dan Li ◽  
Radharaman Ray ◽  
Bal Ram Singh ◽  
James E Keller ◽  
...  
Keyword(s):  
Peptide Delivery ◽  
Therapeutic Peptide ◽  
Synaptic Junctions ◽  
Targeted Therapeutic
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