Metal-Binding Properties of Glycated Proteins and Amino Acids

2005 ◽  
pp. 429 ◽  
Author(s):  
Valeri V Mossine ◽  
Milton S Feather
Keyword(s):  
Amino Acids ◽  
Metal Binding ◽  
Binding Properties ◽  
Glycated Proteins

scholarly journals Amino acids and peptides. XXVI. Synthesis of Agaricus bisporus metallothionein and related peptides and examination of their heavy metal-binding properties.

1990 ◽  
Vol 38 (8) ◽  
pp. 2112-2117 ◽  
Author(s):  
Yasuhiro NISHIYAMA ◽  
Sigeru NAKAYAMA ◽  
Yoshio OKADA ◽  
Kyong-Son MIN ◽  
Satomi ONOSAKA ◽  
...  
Keyword(s):  
Amino Acids ◽  
Heavy Metal ◽  
Metal Binding ◽  
Agaricus Bisporus ◽  
Binding Properties ◽  
Heavy Metal Binding

scholarly journals Enhancing Metal-binding with Noncanonical Coordinating Amino Acids

2021 ◽  
Vol 75 (6) ◽  
pp. 530-534
Author(s):  
Luca Sauser ◽  
Michal S. Shoshan
Keyword(s):  
Amino Acids ◽  
Metal Binding ◽  
Metal Ion ◽  
Chelating Agents ◽  
Binding Properties ◽  
Noncanonical Amino Acids ◽  
Post Translational Modifications ◽  
Synthetic Routes ◽  
Related Proteins ◽  
Proteins And Peptides

More than 50% of proteinogenic amino acid sidechains can bind metal ions, enabling proteins and peptides to bear these ions as cofactors. Nevertheless, post-translational modifications and incorporation of noncanonical amino acids bestow peptides and proteins myriads of other coordination capabilities, thanks to an enhanced metal binding. Here we summarize selected examples of natural and artificial systems that contain one or more noncanonical amino acids coordinating a metal ion and subsequently achieve a new or enhanced function. We report on a wide array of systems: from disease-related proteins that undergo sulfurylation or phosphorylation through natural metallophores that selectively capture precious essential ions to synthetic selfassembly strategies, biocatalysts, and chelating agents against toxic metals. Regardless of their (bio)synthetic routes, all possess unique metal-binding properties that could not be effectively achieved by systems composed of canonical residues.

scholarly journals Amino acids and peptides. XXVII. Synthesis of phytochelatin-related peptides and examination of their heavy metal-binding properties.

1990 ◽  
Vol 38 (9) ◽  
pp. 2364-2368 ◽  
Author(s):  
Yoshikazu MATSUMOTO ◽  
Yoshio OKADA ◽  
Kyong-Son MIN ◽  
Satomi ONOSAKA ◽  
Keiichi Tanaka
Keyword(s):  
Amino Acids ◽  
Heavy Metal ◽  
Metal Binding ◽  
Binding Properties ◽  
Heavy Metal Binding
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