THERAPEUTIC PRINCIPLES FOR STREPTOCOCCUS VIRIDANS INFECTIONS: RECURRENT BACTERIAL ENDOCARDITIS IN A CHILD WITH CONGENITAL HEART DISEASE

PEDIATRICS ◽  
1965 ◽  
Vol 35 (4) ◽  
pp. 704-708
Author(s):  
Welton M. Gersony ◽  
Alexander S. Nadas
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Bacterial Endocarditis ◽  
Intravenous Therapy ◽  
Phenoxymethyl Penicillin ◽  
Serum Bactericidal Activity ◽  
Therapeutic Principles ◽  
Penicillin Therapy ◽  
Principles Of Treatment

A case of recurrent bacterial endocarditis due to a relatively resistant alpha streptococcus is reviewed. The following general principles of treatment are recommended: 1. Intravenous penicillin therapy should be instituted in all instances. 2. Should serum bactericidal levels indicate the organism to be extremely sensitive (< 0.1 units/ml) oral phenoxymethyl penicillin (Penicillin-V) may be substituted after 3 weeks. 3. In cases infected with organisms sensitive to greater than 0.1 units/ml, intravenous therapy should be continued for 6 weeks and streptomycin added for 2 weeks. 4. When facilities for studying penicillin sensitivity and serum bactericidal activity are not available, the intravenous penicillin-streptomycin regime is recommended.

ACUTE INFECTIOUS SINUSITIS IN CYANOTIC CONGENITAL HEART DISEASE

PEDIATRICS ◽  
1973 ◽  
Vol 52 (5) ◽  
pp. 692-696
Author(s):  
Amnon Rosenthal ◽  
Kenneth E. Fellows
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Brain Abscess ◽  
Paranasal Sinuses ◽  
Congenital Heart ◽  
Bacterial Endocarditis ◽  
Cyanotic Congenital Heart Disease ◽  
Hematogenous Spread ◽  
Subacute Bacterial Endocarditis

The prevalance and sequelae of infectious sinusitis in a hospitalized group of children with and without congenital heart disease (CHD) were studied. Sinusitis was more common (1% versus 0.3%) in the CHD group and occurred predominantly (90%) in the cyanotic patients. It was associated with subacute bacterial endocarditis in 20% (5 of 20) and brain abscess in 15% (3 of 20) of the CHD cases. It is postulated that proliferation and distension of the venous channels and marrow spaces in patients with cyanotic CHD enhances the hematogenous spread of bacteria from the paranasal sinuses.

Endocarditis

2017 ◽  
Author(s):  
Sara Thorne ◽  
Sarah Bowater
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Antibiotic Prophylaxis ◽  
Congenital Heart ◽  
Bacterial Endocarditis ◽  
European Guidelines

Nearly all patients with congenital heart disease have a lifelong risk of bacterial endocarditis. This chapter discusses antibiotic prophylaxis, as well as UK and European guidelines.

Bacterial Endocarditis in Patients With Adult Congenital Heart Disease

2013 ◽  
Vol 29 (10) ◽  
pp. S390
Author(s):  
D. Mylotte ◽  
D. Rushani ◽  
L. Guo ◽  
M. Kaouache ◽  
K. Guo ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Bacterial Endocarditis ◽  
Adult Congenital

Endocarditis

2011 ◽  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Dental Hygiene ◽  
Dental Health ◽  
Bacterial Endocarditis ◽  
Valve Surgery ◽  
Expert Advice ◽  
Endocarditis Prophylaxis ◽  
Device Placement

Endocarditis prophylaxis 222Most congenital heart disease patients have a lifelong risk of bacterial endocarditis (Table 18.1) and hence must be educated regarding: • Symptoms that may indicate endocarditis and when to seek expert advice.• Dental health, good oral hygiene, regular brushing, flossing, and need for regular dental check-ups—good dental hygiene and a recent dental check up must be ensured prior to valve surgery or catheter interventions involving device placement....

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