Letters to the Editor

We do not disagree with the recommendations of Drs Fischer, Bass, and Arthur for treating hospitalized patients with pneumonia. They might have mentioned, additionally, the possible utility of cefamandole as an alternative to a penicillinase-resistant penicillin plus chloramphenicol for hospitalized infants with presumed bacterial pneumonia. We are currently evaluating cefuroxime, which has a similar in vitro spectrum, and are finding it effective in patients with pneumonia due to Haemophilus influenzae type b, pneumococci and Staphylococcus aureus.

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Immunoglobulin allotypes and genetic susceptibility to invasive Haemophilus influenzae type b and Staphylococcus aureus infections in South African children

The Pediatric Infectious Disease Journal ◽

10.1097/00006454-199605000-00008 ◽

1996 ◽

Vol 15 (5) ◽

pp. 419-424 ◽

Cited By ~ 4

Author(s):

E. A. GODDARD ◽

D. W. BEATTY ◽

E. B. HOFFMAN

Keyword(s):

Staphylococcus Aureus ◽

Haemophilus Influenzae ◽

Genetic Susceptibility ◽

South African ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Type B ◽

African Children ◽

Immunoglobulin Allotypes ◽

And Staphylococcus Aureus

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Haemophilus influenzae Pneumonia

Pediatrics in Review ◽

10.1542/pir.3.4.105 ◽

1981 ◽

Vol 3 (4) ◽

pp. 105-130

Keyword(s):

Haemophilus Influenzae ◽

Pleural Fluid ◽

Bacterial Pneumonia ◽

Hospitalized Patients ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Purulent Pericarditis ◽

Type B ◽

Pleural Involvement ◽

Treated Child

Haemophilus influenzae type b can cause pneumonia. Although the frequency has not been accurately assessed, this etiology is not rare and may represent as much as one third of hospitalized patients with bacterial pneumonia. Approximately half have pleural involvement. The majority of patients have associated manifestations including otitis, meningitis, purulent pericarditis and epiglottitis. Cultures from the blood and localized areas (pleural fluid, etc) are usually positive and establish the diagnosis. Countercurrent immunoelectrophoresis (CIE) may be helpful in the partially treated child. Comment: H influenzae b can cause a variety of diseases including, obviously more commonly than heretofore believed, pneumonia. Treatment of this illness depends upon the B lactamase production by the isolated Haemophilus.

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Letters to the Editor

PEDIATRICS ◽

10.1542/peds.67.4.581a ◽

1981 ◽

Vol 67 (4) ◽

pp. 581-582

Author(s):

L. Rebecca Campbell ◽

Arnold J. Zedd ◽

Richard H. Michaels

Keyword(s):

Haemophilus Influenzae ◽

Meningococcal Meningitis ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Type B ◽

Letters To The Editor

Dr Walker has presented a concise summary of distinctions between epiglottitis and meningitis due to Haemophilus influenzae type b, suggesting that there may be a difference in pathogenesis for these two conditions. Two epidemiologic distinctions can be added. Ounsted1 has shown that children with Haemophilus meningitis almost invariably have siblings. This is not true for those with pneumococcal or meningococcal meningitis, and it is also not true for children with epiglottitis. 2 There is also a seasonal distinction.>

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Counterimmunoelectrophoresis of Urine for Diagnosis of Bacterial Pneumonia in Pediatric Outpatients

PEDIATRICS ◽

10.1542/peds.71.5.780 ◽

1983 ◽

Vol 71 (5) ◽

pp. 780-783

Author(s):

Ronald B. Turner ◽

Frederick G. Hayden ◽

J. Owen Hendley

Keyword(s):

Haemophilus Influenzae ◽

Bacterial Pneumonia ◽

Clinical Spectrum ◽

Haemophilus Influenzae Type ◽

Haemophilus Influenzae Type B ◽

Type B ◽

Older Children ◽

Pediatric Outpatients ◽

Etiologic Diagnosis

Thirty-eight pediatric outpatients with pneumonia were studied by counterimmunoelectrophoresis for the presence of Haemophilus influenzae type b or pneumococcal antigenuria. Of the 38 patients eight (21%) hadH influenzae type b antigenuria and two (5%) had pneumococcal antigenuria. H influenzae, type b antigenuria was detected more frequently in patients <2 years of age than in older children. Urine counterimmunoelectrophoriesis appears to be a useful tool for the etiologic diagnosis of bacterial pneumonia and should facilitate further studies of the epidemiology, pathogenesis, and clinical spectrum of this disease.

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