Intralesional Corticosteroid Injections for Infantile Hemangiomas of the Eyelid

PEDIATRICS ◽  
1984 ◽  
Vol 74 (2) ◽  
pp. 241-245
Author(s):  
Leonard B. Nelson ◽  
Judith E. Melick ◽  
Robison D. Harley

Infants with capillary hemangiomas of the eyelid are at risk for amblyopia and strabismus. Several methods of treating these tumors have been associated with complications and limitations. The use of intralesional corticosteroid injections has been demonstrated to be a simple, safe, and effective method of treating capillary hemangiomas of the eyelid.

2015 ◽  
Vol 126 (3) ◽  
pp. 549-550 ◽  
Author(s):  
Louis Insalaco ◽  
Sarah Saxon ◽  
Jeffrey H. Spiegel

2019 ◽  
Vol 3 (6) ◽  
pp. 438-442
Author(s):  
James Foshee ◽  
Thomas Griffin ◽  
Kristin Cam ◽  
Michael Rivlin ◽  
Matthew Keller

Nephrogenic systemic fibrosis (NSF) is a sclerotic disorder presenting with painful indurated plaques and skin thickening involving the trunk and extremities, which can lead to tethering and joint contractures.  NSF most commonly affects patients with renal insufficiency who have been exposed to gadolinium. We present a case of NSF involving the bilateral hands, knees, and lower extremities developing over 10 years after gadolinium exposure.  Initial improvement was noted in the lower extremities after initiation of imatinib mesylate therapy, but recalcitrant, thickened hand plaques caused persistent pain and functional limitation. Adjunct intralesional corticosteroid injections produced durable softening of the recalcitrant lesions with considerable functional improvement in hand mobility. Based on our experience, intralesional corticosteroid injections appear to be an effective adjunct treatment in patients with incomplete response to anti-fibrotic therapies.


2012 ◽  
Vol 69 (6) ◽  
pp. 627-632 ◽  
Author(s):  
Jian-Jr Lee ◽  
Li-Ying Lin ◽  
Shun-Wen Hsieh ◽  
Ting-An Chang ◽  
Shiann-Tarng Jou ◽  
...  

2018 ◽  
Vol 6 ◽  
pp. 2050313X1877872 ◽  
Author(s):  
Erika L Crowley ◽  
Ashley O’Toole ◽  
Melinda J Gooderham

Introduction: Hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome are chronic, debilitating diseases involving apocrine gland-bearing skin inflammation and bone inflammation, respectively. Although both often present with multiple comorbidities, single patient co-presentation is rare. Methods/Results: This study reports the 8-year treatment course of a 40-year-old man with hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome, and reviews relevant literature. Initial oral and topical antibiotics had little effect. Intralesional corticosteroid injections were effective for localized inflammatory lesions but insufficient for hidradenitis suppurativa control. Adalimumab initiation and local excision of a persistent HS lesion led to stabilization. Adalimumab provided dramatic back pain improvement. Synovitis, acne, pustulosis, hyperostosis, osteitis was diagnosed; adalimumab continuation with subsequent methotrexate addition resulted in hidradenitis suppurativa-synovitis, acne, pustulosis, hyperostosis, osteitis control. Conclusions: Literature regarding comorbid hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome therapy is scarce but growing. Adalimumab, methotrexate, intralesional corticosteroid, and lifestyle changes successfully maintained a severe hidradenitis suppurativa–synovitis, acne, pustulosis, hyperostosis, osteitis–syndrome case. Further studies beyond a case-based review could yield more definitive treatment plans.


2009 ◽  
Vol 61 (3) ◽  
pp. 537-538 ◽  
Author(s):  
Laura B. Pincus ◽  
Brian S. Schwartz ◽  
Gail Cunningham ◽  
Sadia Saeed ◽  
Timothy G. Berger

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