Neonatal Intracranial Hemorrhage and Phenobarbital

PEDIATRICS ◽  
1987 ◽  
Vol 79 (2) ◽  
pp. 315-315
Author(s):  
KARL C. K. KUBAN ◽  
ELIZABETH BROWN ◽  
ALAN LEVITON ◽  
KALPATHY KRISHNAMOORTHY

In Reply.— We appreciate the comments by Dr Battisti et al. As noted in the inclusion criteria for our study,1 all intubated babies with birth weights less than 1,751 g were eligible for the study. One of the advantages of a randomized double-blind study is that babies with other risk factors, including presence of a fluctuating cerebral blood flow pattern on Doppler ultrasound testing, should have equal chances of being in the treated and placebo groups.

1977 ◽  
Vol 1 (3) ◽  
pp. 225-234 ◽  
Author(s):  
Shinichi Hosokawa ◽  
Yoriaki Yamashita ◽  
Hideo Ueno ◽  
William F. Caveness

1992 ◽  
Vol 20 (6) ◽  
pp. 771-777 ◽  
Author(s):  
JAN BUIJS ◽  
FRANK VAN BEL ◽  
ANNEMARIE NANDORFF ◽  
RUDI HARDJOWIJONO ◽  
THEO STIJNEN ◽  
...  

2005 ◽  
Vol 102 (49) ◽  
pp. 17804-17809 ◽  
Author(s):  
J. Wang ◽  
H. Rao ◽  
G. S. Wetmore ◽  
P. M. Furlan ◽  
M. Korczykowski ◽  
...  

2008 ◽  
Vol 17 (1) ◽  
pp. 82-88 ◽  
Author(s):  
EUN YEON JOO ◽  
WOO SUK TAE ◽  
KI-YOUNG JUNG ◽  
SEUNG BONG HONG

PEDIATRICS ◽  
1987 ◽  
Vol 79 (2) ◽  
pp. 314-315
Author(s):  
O. G. BATTISTI ◽  
J. M. BERTRAND ◽  
J. P. LANGHENDRIES

To the Editor.— We appreciate the recent study by Kuban et al1 about neonatal intracranial hemorrhage and phenobarbital use, but we would like to mention several points. The number of neonates not having been enrolled represents a high proportion of the eligible population (263/554 or 47.5%) from which 48 (8.7%) had hemorrhage before enrollment, suggesting that the inclusion criteria were not sufficient according to the pathophysiology of cerebral blood flow variability in the neonates. In fact, the authors were missing 48/140 (34.3%) of infants with any hemorrhage (the number of infants with any hemorrhage they studied was 92).


2005 ◽  
Vol 22 (3) ◽  
pp. 165-170 ◽  
Author(s):  
A. Schachtrupp ◽  
H. Wrigge ◽  
T. Busch ◽  
W. Buhre ◽  
A. Weyland

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