Cerebral blood flow pattern and autoregtilation during open-heart surgery in infants and young children

1992 ◽  
Vol 20 (6) ◽  
pp. 771-777 ◽  
Author(s):  
JAN BUIJS ◽  
FRANK VAN BEL ◽  
ANNEMARIE NANDORFF ◽  
RUDI HARDJOWIJONO ◽  
THEO STIJNEN ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Young Children ◽  
Flow Pattern ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Blood Flow Pattern ◽  
Infants And Young Children

Spinal Anesthesia with an Indwelling Catheter Reduces the Stress Response in Pediatric Open Heart Surgery

2005 ◽  
Vol 103 (6) ◽  
pp. 1113-1120 ◽  
Author(s):  
Nigel Humphreys ◽  
Simon M. Bays ◽  
Andrew J. Parry ◽  
Ashwinikumar Pawade ◽  
Robert S. Heyderman ◽  
...  
Keyword(s):  
Young Children ◽  
Spinal Anesthesia ◽  
Stress Responses ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Plasma Norepinephrine ◽  
High Dose ◽  
Open Heart ◽  
Extreme Stress ◽  
Infants And Young Children

Background Extreme stress and inflammatory responses to open heart surgery are associated with increased morbidity and mortality. Based on both animal and adult human data, it was hypothesized that spinal anesthesia would be more effective at attenuating these responses than conventional high dose intravenous opioid techniques in infants and young children undergoing open heart surgery. Methods A prospective randomized controlled clinical trial was performed in 60 children aged up to 24 months undergoing open heart surgery. Patients were randomly assigned to receive either high-dose intravenous opioid or high-dose intravenous opioid plus spinal anesthesia. Spinal anesthesia was administered via an indwelling intrathecal catheter. Results Spinal anesthesia significantly reduced the stress responses as measured by plasma norepinephrine and epinephrine concentrations (both P < 0.05). Spinal anesthesia reduced plasma lactate concentrations (P < 0.05), but increased fluid requirements during the first postoperative day (P < 0.05). There were no differences in other cardiovascular parameters. Conclusions Continuous spinal anesthesia reduces stress responses in infants and young children undergoing cardiac surgery with cardiopulmonary bypass more effectively than high-dose intravenous opioids alone.

Internal Jugular Bulb Blood Velocity as a Continuous Indicator of Cerebral Blood Flow during Open Heart Surgery

1994 ◽  
Vol 81 (2) ◽  
pp. 325-332 ◽  
Author(s):  
Hisatoshi Ohsumi ◽  
Katsuyasu Kitaguchi ◽  
Toshito Nakajima ◽  
Yoshihiko Ohnishi ◽  
Masakazu Kuro
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Jugular Bulb ◽  
Blood Velocity ◽  
Open Heart

scholarly journals CEREBRAL BLOOD FLOW MEASURED BY NEAR INFRARED SPECTROSCOPY (NIRS) IN CHILDREN UNDERGOING OPEN HEART SURGERY

1994 ◽  
Vol 35 (2) ◽  
pp. 259-259
Author(s):  
Penny Fallen ◽  
Idris Roberts ◽  
Richard Maynard ◽  
Adrian Lloyd-Thomas ◽  
Martin J Elliott ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Heart Surgery ◽  
Near Infrared ◽  
Open Heart Surgery ◽  
Open Heart

scholarly journals Effect of Open-Heart Surgery on the Body Composition of Infants and Young Children

1981 ◽  
Vol 15 (7) ◽  
pp. 1024-1028 ◽  
Author(s):  
Yves W Brans ◽  
Harry S Dweck ◽  
Howard B Harris ◽  
Grant V S Parr ◽  
Penrhyn E Bailey ◽  
...  
Keyword(s):  
Body Composition ◽  
Young Children ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
The Body ◽  
Open Heart ◽  
Infants And Young Children

Neonatal Intracranial Hemorrhage and Phenobarbital

PEDIATRICS ◽  
1987 ◽  
Vol 79 (2) ◽  
pp. 315-315
Author(s):  
KARL C. K. KUBAN ◽  
ELIZABETH BROWN ◽  
ALAN LEVITON ◽  
KALPATHY KRISHNAMOORTHY
Keyword(s):  
Risk Factors ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Pattern ◽  
Intracranial Hemorrhage ◽  
Double Blind Study ◽  
Inclusion Criteria ◽  
Blood Flow Pattern ◽  
Double Blind ◽  
Ultrasound Testing

In Reply.— We appreciate the comments by Dr Battisti et al. As noted in the inclusion criteria for our study,1 all intubated babies with birth weights less than 1,751 g were eligible for the study. One of the advantages of a randomized double-blind study is that babies with other risk factors, including presence of a fluctuating cerebral blood flow pattern on Doppler ultrasound testing, should have equal chances of being in the treated and placebo groups.

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