Clinical Monitoring of Inhaled Nitric Oxide
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Inhaled nitric oxide (NO) is being increasingly utilized for the treatment of pulmonary hypertension and ventilation-perfusion mismatch in association with respiratory failure in adults, children, and neonates.1,2 The three major areas of potential toxicity of NO are the formation of methemoglobin, the production of free radicals such as peroxynitrite, and the formation of nitrogen dioxide (NO2) by reaction with oxygen (O2) in the delivery system. NO2 is toxic,3 with a maximum 8-hour, time-weighted, average exposure recommendation of 5 ppm.4
2003 ◽
Vol 12
(2)
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pp. 147-153
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2018 ◽
Vol 46
(6)
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pp. 657-663
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1995 ◽
Vol 38
(2)
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pp. 198-204
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2018 ◽
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