Histologic and Histometric Evaluation of Bovine Cancellous Bone and Beta-Tricalcium Phosphate 45 Months After Grafting in Maxillary Sinus

2011 ◽  
Vol 37 (6) ◽  
pp. 727-733 ◽  
Author(s):  
Farokh Khatiblou

The aim of this report is to determine the long-term histologic and histometric evaluation of beta-tricalcium phosphate (beta-TCP) and bovine cancellous bone grafted into the left maxillary sinus of a patient in order to augment the sinus floor to prepare it for receiving an implant. Beta-TCP and bovine cancellous bone (BCB) were grafted into the left maxillary sinus at the extracted sites of maxillary left first and second molars of a 62-year-old male patient. Using osteotome technique, 45 months later, core biopsies were taken for histologic and histometric comparison of the newly formed bone. Histometric and histologic evaluation of both specimens revealed a normal maxillary bone structure with 23.08% calcified bone and 76.92% marrow and connective tissue for the beta-TCP grafted site, and 24.81% calcified bone with 75.19% marrow and connective tissue for the BCB grafted site. No residual grafting material was seen in either specimen. Both beta-TCP and BCB were completely resorbed and replaced by new bone 45 months after grafting. Histologic results of the newly formed bone were similar for both grafting materials.

2016 ◽  
Vol 694 ◽  
pp. 94-98 ◽  
Author(s):  
Wai Yee Wong ◽  
Ahmad Fauzi Mohd Noor ◽  
Radzali Othman

Porous beta-tricalcium phosphate (β-TCP) bioceramic has been reported as synthetic graft for cancellous bone substitute due to its biocompatibility and biodegradability properties. A highly porous and interconnected porosity architecture of bone scaffold facilitates attachment and in-growth of new bone tissue. β-TCP foam, a porous 3-dimensional scaffold was fabricated by employing polymeric foam replica method in this study. Polyurethane (PU) foam was used as the sacrificial template, in which β-TCP slurry with powder to water ratio of 10g:10ml was coated on PU template and sintered to 1100, 1200, 1250 and 1300°C. Observation on architecture of the foam, macrostructure and microstructure of pores and surface topography of porous strut showed that sintering at 1250°C produced sufficient densification of grains and micropores on the β-TCP strut. The β-TCP foams exhibited high porosity (92 – 97%) and large pore size (200 - 750um) that resemble cancellous bone structure.


Author(s):  
Eugenio Velasco-Ortega ◽  
Angela Sierra-Baztan ◽  
Alvaro Jiménez-Guerra ◽  
Antonio España-López ◽  
Iván Ortiz-Garcia ◽  
...  

Introduction. The aim of this study was to show the long-term clinical outcomes of implants placed in maxillary sinus floor augmentation (MFSA) using beta-tricalcium phosphate (β-TCP). Patients and methods. Maxillary patients were diagnosed for MFSA and used beta- β-TCP. After the lateral sinus surgery, implants were loaded at 6 months with restorations. The clinical follow-up was at 10 years. Results. One hundred and one patients (58 females and 43 males) were treated with MFSA. Twenty-nine patients (28.7%) had a history of periodontitis. Thirty-three patients (32.7%) were smokers. One hundred and twenty-one MFSA, 81 unilateral and 20 bilateral sites, with 234 implants were performed. The average vertical bone height available was 4.92 ± 1.83 mm. The average vertical bone gain obtained was 6.95 ± 2.19 mm following MFSA. The implant cumulative survival rate was 97.2%. Three implants (1.3%) were lost during the healing period. Six implants (2.6%) were lost by peri-implantitis. One hundred and fifteen restorations were placed in the patients. Mean marginal bone loss was 1.93 mm ± 1.03 mm. Six patients (27.3%) showed technical complications. Thirty-six implants (15.3%) in 14 patients (13.9%) were associated with peri-implantitis. Conclusions. This study indicates that treatment with implant-supported restoration by MFSA using β-TCP constitutes a successful implant approach.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Valentina Fatale ◽  
Stefano Pagnoni ◽  
Albino Emidio Pagnoni ◽  
Pier Carmine Passarelli ◽  
Andrea Netti ◽  
...  

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