scholarly journals Granulomatous slack skin T-cell lymphoma: an important differential diagnosis with giant cell tumor of soft tissue

2015 ◽  
Vol 90 (6) ◽  
pp. 892-895
Author(s):  
André Ricardo Adriano ◽  
Tiago Silveira Lima ◽  
Maxime Battistella ◽  
Martine Bagot



1996 ◽  
Vol 10 (4) ◽  
pp. 239-246
Author(s):  
Anders Cervin ◽  
Michael Dictor ◽  
Olof Kalm

The clinical course of 12 patients with sinonasal T-cell lymphoma retrospectively diagnosed using in situ hybridization for Epstein-Barr virus RNA was compared with that of 10 recently treated patients with Wegener's granulomatosis (WG) in the upper airways. In particular, we studied the presenting signs and symptoms of both diseases, which commonly offer a problem in differential diagnosis at the clinical and pathological level. A bimodal age distribution was suggested in both T-cell lymphoma and WG; five patients with T-cell lymphoma developed disease prior to 40 years of age. Four of the 12 lymphoma patients had a history of “chronic rhinitis” for several years before developing mucosal ulcerations, which were initially unilateral, as opposed to the bilateral ulcerations in early sinonasal WG. Two lymphoma patients had swelling of the nasal dorsum and cheek. In contrast to the WG patients, cases of T-cell lymphoma did not exhibit associated clinical signs of arthritis, conjunctivitis, pulmonary lesions, or nephritis in the early stage of the disease. Nine of the patients with T-cell lymphoma presenting as a sinonasal lesion developed disseminated disease, variably including infiltrates in intestine, lung, CNS, and skin. Four of these patients died from gastrointestinal complications of their disease. We conclude that unilateral ulcerative or hemorrhagic polypoid mucosal lesions in the sinonasal area are suggestive of lymphoma rather than WG, and nonspecific symptoms, at least in Western patients, may be present as early as the second or third decade of life. A biopsy specimen containing T lymphocytes positive for the EBV ribonucleoprotein EBER1 on in situ hybridization offers reliable confirmation of T-cell lymphoma and is of differential diagnostic value against WG.



2014 ◽  
Vol 30 (1) ◽  
pp. 73 ◽  
Author(s):  
Aylin Orgen Calli ◽  
Mine Tunakan ◽  
Huseyin Katilmis ◽  
Sevil Kilciksiz ◽  
Sedat Ozturkcan


2003 ◽  
Vol 47 (6) ◽  
pp. 1103-1106 ◽  
Author(s):  
Na Rae Kim ◽  
Joungho Han


2010 ◽  
Vol 16 (3) ◽  
Author(s):  
Victoria Nguyen ◽  
Carlos Garcia ◽  
Henry Haskell


2020 ◽  
Vol 9 (1) ◽  
pp. 120-123
Author(s):  
Debasis Gochhait ◽  
Shailesh Kekade ◽  
Durga Devi ◽  
Bheemanathi Hanuman Srinivas ◽  
Neelaiah Siddaraju ◽  
...  


2007 ◽  
Vol 34 (1) ◽  
pp. 102-104 ◽  
Author(s):  
SELMA SONMEZ ERGUN ◽  
NESIMI BUYUKBABANI ◽  
ULVIYE ATILGANOGLU


2008 ◽  
Vol 12 (6) ◽  
pp. 299-301
Author(s):  
Mark A. Lomaga ◽  
Scott Walsh

Background: There are two rare variants of cutaneous T-cell lymphoma (CTCL) that primarily involve the subcutis. These include subcutaneous panniculitis-like T-cell lymphoma (SPTL) and cutaneous γ/δ T-cell lymphoma. Objective: This case report describes the clinical presentation, diagnosis, and treatment of a young man with probable SPTL. A review of recent literature outlining the differences between SPTL and cutaneous γ/δ T-cell lymphoma is discussed. Conclusion: The differential diagnosis in patients presenting with subcutaneous nodules and constitutional symptoms should include CTCL.



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