Renal Nerve Ablation in Nephritis and Beyond

2021 ◽  
Vol 32 (10) ◽  
pp. 2393-2395
Author(s):  
Kristina Rodionova ◽  
Tilmann Ditting ◽  
Roland Veelken
Keyword(s):  
Renal Nerve ◽  
Renal Nerve Ablation

Renal nerve ablation reduces blood pressure in a patient with renovascular hypertension resistant to drug and revascularisation therapies

2012 ◽  
Vol 159 (2) ◽  
pp. e35-e36 ◽  
Author(s):  
Dagmara Hering ◽  
Anthony Walton ◽  
Henry Krum ◽  
Gavin W. Lambert ◽  
Murray D. Esler ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renovascular Hypertension ◽  
Renal Nerve ◽  
Renal Nerve Ablation

Device-based treatment for hypertension

ESC CardioMed ◽  
2018 ◽  
pp. 2458-2465
Author(s):  
Saarraaken Kulenthiran ◽  
Sebastian Ewen ◽  
Felix Mahfoud
Keyword(s):  
Weight Control ◽  
Treatment Options ◽  
Arteriovenous Anastomosis ◽  
Renal Nerve ◽  
Novel Device ◽  
Adherence To Medication ◽  
Carotid Baroreceptor ◽  
Improved Outcomes ◽  
Renal Nerve Ablation ◽  
Novel Drug

Autonomic imbalance is thought to play an important role in the pathophysiology of hypertension. Despite the availability of diverse pharmacological options, non-adherence to medication or inability to tolerate current pharmacological therapies has led to the development of various device-based therapy options. Inhibiting components of the sympathetic nervous system offers a unique opportunity to target the ‘neural’ component of the neurohormonal axis. Combining novel drug-, device-, and procedure-based strategies with improved utilization of existing therapies (including appropriate attention to diet, exercise, and weight control) may result in improved outcomes. This chapter discusses the rationale and current experimental and clinical data of several novel device-based treatment options—renal nerve ablation, carotid body ablation, carotid baroreceptor stimulation, and central arteriovenous anastomosis.

Device-based treatment for hypertension

ESC CardioMed ◽  
2018 ◽  
pp. 2458-2465
Author(s):  
Saarraaken Kulenthiran ◽  
Sebastian Ewen ◽  
Felix Mahfoud
Keyword(s):  
Weight Control ◽  
Treatment Options ◽  
Arteriovenous Anastomosis ◽  
Renal Nerve ◽  
Novel Device ◽  
Adherence To Medication ◽  
Carotid Baroreceptor ◽  
Improved Outcomes ◽  
Renal Nerve Ablation ◽  
Novel Drug

Autonomic imbalance is thought to play an important role in the pathophysiology of hypertension. Despite the availability of diverse pharmacological options, non-adherence to medication or inability to tolerate current pharmacological therapies has led to the development of various device-based therapy options. Inhibiting components of the sympathetic nervous system offers a unique opportunity to target the ‘neural’ component of the neurohormonal axis. Combining novel drug-, device-, and procedure-based strategies with improved utilization of existing therapies (including appropriate attention to diet, exercise, and weight control) may result in improved outcomes. This chapter discusses the rationale and current experimental and clinical data of several novel device-based treatment options—renal nerve ablation, carotid body ablation, carotid baroreceptor stimulation, and central arteriovenous anastomosis.

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

2013 ◽  
Vol 31 (9) ◽  
pp. 1893-1900 ◽  
Author(s):  
Dagmara Hering ◽  
Elisabeth A. Lambert ◽  
Petra Marusic ◽  
Carolina Ika-Sari ◽  
Antony S. Walton ◽  
...  
Keyword(s):  
Resistant Hypertension ◽  
Augmentation Index ◽  
Renal Nerve ◽  
Renal Nerve Ablation

scholarly journals Clinical Diagnosis and Management of Resistant Hypertension

2016 ◽  
Vol 11 (1) ◽  
pp. 12 ◽  
Author(s):  
Costas P Tsioufis ◽  
Alexandros Kasiakogias ◽  
Dimitrios Tousoulis ◽  
◽  
◽  
...  
Keyword(s):  
Resistant Hypertension ◽  
Treatment Resistance ◽  
Multiple Drug ◽  
Lifestyle Modifications ◽  
Renal Nerve ◽  
Invasive Approach ◽  
Initial Management ◽  
Aldosterone Antagonist ◽  
Treatment Prevalence ◽  
Renal Nerve Ablation

Resistant hypertension (RHT) is variably defined as insufficient blood pressure (BP) response to multiple drug treatment. Prevalence of RHT has been thoroughly studied in the recent years, ranging from about 5 to 30 % in various cohorts. Initial management of patients with apparent RHT requires identification of true treatment resistance by out-of-office BP measurements, assessment of adherence and screening for treatable causes of uncontrolled BP. Endorsement of lifestyle modifications and maximisation of the doses of a suitable regimen, preferably with the further addition of an aldosterone antagonist, are the mainstay of treatment. An invasive approach to RHT, mainly represented by renal nerve ablation, should be kept for persistently severe cases managed in a specialised hypertension centre.

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