Letter Report - Review of Analysis Plan for the Hanford Thyroid Disease Study (HTDS)

10.17226/9529 ◽  
1998 ◽  
Keyword(s):  
Thyroid Disease ◽  
Disease Study

ESTIMATION OF THYROID RADIATION DOSES FOR THE HANFORD THYROID DISEASE STUDY: RESULTS AND IMPLICATIONS FOR STATISTICAL POWER OF THE EPIDEMIOLOGICAL ANALYSES

2004 ◽  
Vol 87 (1) ◽  
pp. 15-32 ◽  
Author(s):  
Kenneth J. Kopecky ◽  
Scott Davis ◽  
Thomas E. Hamilton ◽  
Mark S. Saporito ◽  
Lynn E. Onstad
Keyword(s):  
Thyroid Disease ◽  
Statistical Power ◽  
Radiation Doses ◽  
Study Results ◽  
Disease Study

Locating Members of a Cohort Identified Retrospectively From Limited Data in 50-Year-Old Records: Successful Approaches Employed by the Hanford Thyroid Disease Study

2008 ◽  
Vol 18 (3) ◽  
pp. 187-195 ◽  
Author(s):  
Scott Davis ◽  
Lynn Onstad ◽  
Kenneth J. Kopecky ◽  
Charles Wiggins ◽  
Thomas E. Hamilton
Keyword(s):  
Thyroid Disease ◽  
Limited Data ◽  
Disease Study

Review of the Hanford Thyroid Disease Study Draft Final Report

2000 ◽  
Vol 20 (2) ◽  
pp. 253-254
Author(s):  
Richard Wakeford
Keyword(s):  
Thyroid Disease ◽  
Final Report ◽  
Disease Study

scholarly journals MALIGNANT THYROID DISEASE;

2017 ◽  
Vol 24 (12) ◽  
pp. 1794-1800
Author(s):  
Altaf Ahmed Talpur ◽  
Bheesham Kumar ◽  
Ahsan Ali Laghari ◽  
Abdul Qadeer Shikh ◽  
Afzal Junejo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Surgical Procedures ◽  
Thyroid Surgery ◽  
Thyroid Disease ◽  
Cervical Lymph Node ◽  
Thyroid Malignancy ◽  
Node Dissection ◽  
Postoperative Hypocalcemia ◽  
Permanent Hypocalcemia ◽  
Disease Study

Objectives: To determine frequency of Transient & permanent hypocalcemiaafter Thyroid Surgery for Malignant thyroid disease. Study Design: Observational study.Setting: Public & Private Sector Hospitals of Hyderabad. Period: December 2008 to April 2016.Materials and Methods: All patients of Thyroid pathology who fulfilled the inclusion criteriawere admitted in the ward. They were evaluated preoperatively & surgery was performed.Postoperatively patients were assessed clinically & biochemically for Hypocalcaemia. Patient’sdata was recorded & analyzed for variables like age, sex, diagnosis of thyroid disease on FNAC,Type of thyroid Malignancy, type of thyroid surgery, Transient & permanent hypocalcemia inrelation to type of type of thyroid surgery performed & the hospital stay. Results: Total 254patients were operated for different thyroid pathologies. It includes 91(35.82%) male & and163 (64.17%) female patients making ratio of 1: 1.79. Mean age was 37.29 ±7.4 years.Amongst them 33 patients were diagnosed as Malignant Thyroid diseases. Most commontype of thyroid malignancy detected was papillary carcinoma in 48.48% patients followed byfollicular carcinoma in 42.42% patients. Most common surgical procedures performed includescompletion thyroidectomy in 57.57% patients with 01(3.03%) of them underwent cervicalneck dissection followed by total thyroidectomy in 36.36% patients with 02(6.06%) of themunderwent cervical neck dissection. Postoperative hypocalcemia was noted in 45.45% patientswith 36.36% patients developed hypocalcemia within 24 hours of operation, 6.06% within 24to 48 hours & 3.03% patients after 48 hours of surgery. Transient hypocalcemia was noticed in13/33 (39.39%) cases & permanent hypocalcemia in 02/33(6.06%) patients. Mean hospital staywas 4.13± 0.32 days. Conclusion: Hypocalcaemia was noted in 15(45.45%) patients operatedfor thyroid Malignancy. Revision surgery & cervical lymph node dissection were noted as riskfactors.

Final Report of Hanford Thyroid Disease Study Released

2002 ◽  
Vol 94 (14) ◽  
pp. 1046-1048 ◽  
Author(s):  
T. Reynolds
Keyword(s):  
Thyroid Disease ◽  
Final Report ◽  
Disease Study

scholarly journals Application of Data Science Approaches to Investigate Autoimmune Thyroid Disease in Precision Medicine

2021 ◽  
Author(s):  
Ayodeji Folorunsho Ajayi ◽  
Emmanuel Tayo Adebayo ◽  
Iyanuoluwa Oluwadunsi Adebayo ◽  
Olubunmi Simeon Oyekunle ◽  
Victor Oluwaseyi Amos ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Big Data ◽  
Precision Medicine ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Data Science ◽  
Genetic Difference ◽  
Genetic Data ◽  
Autoimmune Thyroid ◽  
Disease Study

In recent times, the application of artificial intelligence in facilitating, capturing, and restructuring Big data has transformed the accuracy of diagnosis and treatment of diseases, a field known as precision medicine. Big data has been established in various domains of medicine for example, artificial intelligence has found its way into immunology termed as immunoinformatics. There is evidence that precision medicine tools have made an effort to accurately detect, profile, and suggest treatment regimens for thyroid dysfunction using Big data such as imaging and genetic sequences. In addition, the accumulation of data on polymorphisms, autoimmune thyroid disease, and genetic data related to environmental factors has occurred over time resulting in drastic development of clinical autoimmune thyroid disease study. This review emphasized how genetic data plays a vital role in diagnosing and treating diseases related to autoimmune thyroid disease like Graves’ disease, subtle subclinical thyroid dysfunctions, Hashimoto’s thyroiditis, and hypothyroid autoimmune thyroiditis. Furthermore, connotation between environmental and endocrine risk factors in the etiology of the disease in genetically susceptible individuals were discussed. Thus, endocrinologists’ potential hurdles in cancer and thyroid nodules field include unreliable biomarkers, lack of distinct therapeutic alternatives due to genetic difference. Precision medicine data may improve their diagnostic and therapeutic capabilities using artificial intelligence.

Sign in / Sign up

Export Citation Format

Share Document