Toxic Epidermal Necrolysis. A case report

2010 ◽  
Vol 35 (2) ◽  
pp. 197-198 ◽  
Author(s):  
Patricia Villalta ◽  
Ines Velez ◽  
Lina Mejia ◽  
Ana Maria Ospina

We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the epithelium. Severe sequelae, including blindness, hearing loss, tooth malformation and esophageal destruction are seen in this case.

2021 ◽  
Vol 12 (Supp 1) ◽  
pp. 26-29
Author(s):  
Thomas Schiestel

Bullous drug eruptions such as Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare but known adverse reactions of fluoroquinolones. Although uncommon, TEN can be life-threatening for the patient, especially in the context of delayed treatment and in fragile patients such as the pediatric population. In the present case, TEN occurred in a 13-year-old girl with no medical history following initiation of ciprofloxacin treatment for an inguinal cyst. We hope that the case report will make interrogate the practices concerning the use of antibiotics, in particular fluoroquinolones in the context of an use not prescribed by the Marketing Authorization of the drug in children.


2021 ◽  
Vol 12 (12) ◽  
pp. 421-426
Author(s):  
Sharjeel Israr ◽  
Christopher R. Mellon ◽  
Haley J. Springs ◽  
Asia N. Quan ◽  
Marc R. Matthews

Author(s):  
Lalkota Prakash Bhanu ◽  
Kumara Swamy M. ◽  
Mohammed Nasiruddin ◽  
Naveen H. D. ◽  
Rajesh Venkataraman

Stevens-Johnson syndrome (SJS) and Toxic epidermal necrolysis (TEN) are rare (one to two per 10,00,00 population per year) but life threatening adverse drug reactions. Antiepileptic drugs-induced Stevens-Johnson syndrome (SJS) is a life-threatening severe cutaneous adverse reaction, amongst anti-epileptics; carbamazepine and phenytoin are the major culprits. We report here a case of SJS due to phenytoin (CTC vs 2 Grade 3).


2010 ◽  
Vol 100 (4) ◽  
pp. 299-303 ◽  
Author(s):  
Michael R. Langlois ◽  
Francis Derk ◽  
Ronald Belczyk ◽  
Thomas Zgonis

Stevens-Johnson syndrome and toxic epidermal necrolysis are rare; however, when they occur, they usually present with severe reactions in response to medications and other stimuli. These reactions are characterized by mucocutaneous lesions, which ultimately lead to epidermal death and sloughing. We present a unique case report of Stevens-Johnson syndrome and associated toxic epidermal necrolysis in a 61-year-old man after treatment for a peripherally inserted central catheter infection with trimethoprim-sulfamethoxazole. This case report reviews a rare adverse reaction to a commonly prescribed antibiotic drug used in podiatric medical practice for the management of diabetic foot infections. (J Am Podiatr Med Assoc 100(4): 299–303, 2010)


2014 ◽  
Vol 04 (04) ◽  
pp. 102-103
Author(s):  
Babu Dharmarajan ◽  
Sanil Varghese ◽  
Sachina B. T.

AbstractStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are a rare disease which is considered to be more devastating and fatal in nature. Usually symptoms may start with the involvement of epidermis and progress to the various manifestations. Early findings, symptomatic and supportive treatment will have the more positive impact on the outcome of the client.


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