scholarly journals Neuropsychiatric lupus

2021 ◽  
Vol 7 (2) ◽  
pp. 41-48
Author(s):  
Claudia Centurión-Wenninger
Keyword(s):  
Neuropsychiatric Lupus

Immunological Mechanisms of Neuropsychiatric Lupus

2015 ◽  
Vol 11 (2) ◽  
pp. 93-106 ◽  
Author(s):  
Kyle Sinclair ◽  
Jonathan Miner ◽  
Alfred Kim
Keyword(s):  
Neuropsychiatric Lupus ◽  
Immunological Mechanisms

scholarly journals FRI0128 The age distribution of the focal hyperintensities in brain mr in patients with neuropsychiatric lupus

2001 ◽  
Author(s):  
V Peterová ◽  
C Dostál ◽  
Z Seidl ◽  
T Viták ◽  
J Obenberger ◽  
...  
Keyword(s):  
Age Distribution ◽  
Neuropsychiatric Lupus

scholarly journals Autoantibodies in neuropsychiatric lupus: still looking

Rheumatology ◽  
2018 ◽  
Vol 58 (5) ◽  
pp. 746-747 ◽  
Author(s):  
Shamik Bhattacharyya
Keyword(s):  
Neuropsychiatric Lupus

AB0215 Experimental neuropsychiatric lupus induced by 16/6 idiotype antibodies

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 649.16-649
Author(s):  
S. Kivity ◽  
A. Katzav ◽  
M. Teresa-Arango ◽  
M. Rabi ◽  
Y. Zafrir ◽  
...  
Keyword(s):  
Neuropsychiatric Lupus

Brain MRI in neuropsychiatric lupus: associations with the 1999 ACR case definitions

2014 ◽  
Vol 35 (5) ◽  
pp. 861-869 ◽  
Author(s):  
Hae Woong Jeong ◽  
Minyoung Her ◽  
Jong Seok Bae ◽  
Seong-Kyu Kim ◽  
Sung Won Lee ◽  
...  
Keyword(s):  
Brain Mri ◽  
Neuropsychiatric Lupus ◽  
Case Definitions

scholarly journals THE ROLE OF ANTI-B CELL THERAPY IN THE RAPID AND EFFECTIVE CONTROL OF NEUROPSYCHIATRIC LUPUS

2019 ◽  
Author(s):  
VICTÓRIA CARNEIRO DAL MORO ◽  
IHAN BRUNO LOPES RABELO ◽  
FILIPE AUGUSTO CARVALHO DE PAULA ◽  
SILVIA LARISSA SANTOS ◽  
FERNANDO ANTÔNIO BOTONI ◽  
...  
Keyword(s):  
Cell Therapy ◽  
B Cell ◽  
Effective Control ◽  
Neuropsychiatric Lupus

scholarly journals Neuropsychiatric lupus: The devil is in the detail

2019 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
MamtaB Singh ◽  
Arunmozhimaran Elavarasi ◽  
Padma Srivastava ◽  
Vinay Goyal
Keyword(s):  
Neuropsychiatric Lupus ◽  
The Devil

Ribosomal P antibody: 30 years on the road

Lupus ◽  
2017 ◽  
Vol 26 (5) ◽  
pp. 453-462 ◽  
Author(s):  
V T Viana ◽  
L Durcan ◽  
E Bonfa ◽  
K B Elkon
Keyword(s):  
Lupus Erythematosus ◽  
Age Of Onset ◽  
Direct Injection ◽  
Experimental Studies ◽  
Clinical Manifestations ◽  
Cross Reactivity ◽  
Neuropsychiatric Lupus ◽  
Protein Antigens ◽  
Systemic Lupus ◽  
On The Road

The identity of the protein antigens targeted by anti-cytoplasmic antibodies in lupus was discovered 30 years ago. These antigens are three acidic ribosomal phosphoproteins, P0, P1, and P2. Precise identification of the shared epitope on these three proteins enabled sensitive and specific immunoassays to be developed. Anti-P antibodies are highly specific for systemic lupus erythematosus (SLE) and occur in 15%–35% of patients, depending on ethnicity as well as the age of onset. Increased frequencies of detection of anti-P have been reported in childhood SLE as well as in neuropsychiatric, renal, and hepatic disease. While longitudinal studies by the Systemic Lupus International Collaborating Clinics (SLICC) consortium supported the association of anti-P with neuropsychiatric lupus, the predictive value of antibody determination remains controversial. This is likely explained by the heterogeneity of neuropsychiatric lupus as well as by the different methodologies used for assay. A number of experimental studies have suggested a direct pathogenic role for anti-P antibodies in brain disease. Findings include cross reactivity between anti-P and a neuronal surface antigen, which was detected in areas of the brain involved in memory, cognition, and emotion. Direct injection of anti-P antibodies into the brains of rodents was also associated with abnormal electrical activity and behavioral disturbances. Taken together, research over the last 30 years has established anti-P antibodies as a useful diagnostic marker of SLE and at least a subset of patients with neuropsychiatric disease. Further research is required to fine tune the association of anti-P with clinical manifestations and establish beyond high probability a pathophysiologic role for the antibodies.

scholarly journals PS10:182 Nmda-positive neuropsychiatric lupus manifesting as weight increase and hyposmia

2018 ◽  
Author(s):  
C Pamfil ◽  
S Rednic ◽  
I Catana ◽  
M Deac Badaranza ◽  
D Balint Gib ◽  
...  
Keyword(s):  
Weight Increase ◽  
Neuropsychiatric Lupus

scholarly journals A20/TNFAIP3 heterozygosity predisposes to behavioral symptoms in a mouse model for neuropsychiatric lupus

2020 ◽  
Vol 2 ◽  
pp. 100018
Author(s):  
C. Daems ◽  
M. Sékulic ◽  
V. Vulsteke ◽  
G. van Loo ◽  
R. D’Hooge ◽  
...  
Keyword(s):  
Mouse Model ◽  
Behavioral Symptoms ◽  
Neuropsychiatric Lupus
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