Synthesis and biological evaluation of conformationally constrained sphingosine-1-phosphate analogs as subtype selective S1P receptor agonist/antagonist

Mapping Intimacies ◽

10.18130/v3wg9m ◽

2008 ◽

Author(s):

Ran Zhu

Keyword(s):

Receptor Agonist ◽

Biological Evaluation ◽

Conformationally Constrained ◽

Sphingosine 1 Phosphate ◽

S1p Receptor ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Faculty Opinions recommendation of Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1064759.517678 ◽

2007 ◽

Author(s):

Hugh Rosen

Keyword(s):

Biological Evaluation ◽

Receptor Agonists ◽

Sphingosine 1 Phosphate ◽

Subtype Selective ◽

Synthesis And Biological Evaluation ◽

Receptor Agonists And Antagonists

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Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.10.060 ◽

2007 ◽

Vol 15 (2) ◽

pp. 663-677 ◽

Author(s):

Frank W. Foss ◽

Ashley H. Snyder ◽

Michael D. Davis ◽

Michael Rouse ◽

Mark D. Okusa ◽

...

Keyword(s):

Biological Evaluation ◽

Receptor Agonists ◽

Sphingosine 1 Phosphate ◽

Subtype Selective ◽

Synthesis And Biological Evaluation ◽

Receptor Agonists And Antagonists

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Synthesis of 2,3-Dihydrofuro[3,2-c]pyridine-3,4-dicarboxylic Acid, a Conformationally Constrained Analogue of the Subtype Selective NMDA Receptor Agonist Homoquinolinic Acid

Heterocycles ◽

10.3987/com-04-s(p)22 ◽

2004 ◽

Vol 64 (1) ◽

pp. 261 ◽

Author(s):

Robert H. Dodd ◽

Marcus Vinicius Nora de Souza ◽

Zhaohua Yan

Keyword(s):

Nmda Receptor ◽

Dicarboxylic Acid ◽

Receptor Agonist ◽

Conformationally Constrained ◽

Subtype Selective

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Effects of fingolimod, a sphingosine-1-phosphate (S1P) receptor agonist, on white matter microstructure, cognition and symptoms in schizophrenia

Brain Imaging and Behavior ◽

10.1007/s11682-020-00375-7 ◽

2020 ◽

Author(s):

Michael M. Francis ◽

Tom A. Hummer ◽

Emily Liffick ◽

Jenifer L. Vohs ◽

Nikki F. Mehdiyoun ◽

...

Keyword(s):

White Matter ◽

Receptor Agonist ◽

White Matter Microstructure ◽

Sphingosine 1 Phosphate ◽

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Design, synthesis, and biological evaluation of conformationally constrained glycerol 3-phosphate acyltransferase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.06.091 ◽

2010 ◽

Vol 18 (17) ◽

pp. 6470-6479 ◽

Author(s):

Edward A. Wydysh ◽

Aravinda Vadlamudi ◽

Susan M. Medghalchi ◽

Craig A. Townsend

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Conformationally Constrained ◽

Acyltransferase Inhibitors ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of sphingosine-1-phosphate receptor 2 antagonists as potent 5-FU-resistance reversal agents for the treatment of colorectal cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113775 ◽

2021 ◽

pp. 113775

Author(s):

Dongdong Luo ◽

Yuhang Zhang ◽

Shuang Yang ◽

Xiaochen Tian ◽

Yan Lv ◽

...

Keyword(s):

Colorectal Cancer ◽

Biological Evaluation ◽

Design Synthesis ◽

Reversal Agents ◽

Resistance Reversal ◽

Sphingosine 1 Phosphate ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.11.036 ◽

2006 ◽

Vol 14 (7) ◽

pp. 2462-2467 ◽

Author(s):

Stuart T. Hazeldine ◽

Lisa Polin ◽

Juiwanna Kushner ◽

Kathryn White ◽

Thomas H. Corbett ◽

...

Keyword(s):

Antitumor Agents ◽

Biological Evaluation ◽

Conformationally Constrained ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of novel cyclopropyl derivatives as subtype-selective ligands for estrogen receptor

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.12908 ◽

2018 ◽

Vol 70 (7) ◽

pp. 910-918 ◽

Author(s):

Zunyuan Wang ◽

Yewei Yang ◽

Xiaoliang Zheng ◽

Tao Zhang ◽

Wenhai Huang ◽

...

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Selective Ligands ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Computer-Aided Molecular Modeling, Synthesis, and Biological Evaluation of 8-(Benzyloxy)-2-phenylpyrazolo[4,3-c]quinoline as a Novel Benzodiazepine Receptor Agonist Ligand

Journal of Medicinal Chemistry ◽

10.1021/jm00006a014 ◽

1995 ◽

Vol 38 (6) ◽

pp. 950-957 ◽

Author(s):

C. G. Wang ◽

T. Langer ◽

P. G. Kamath ◽

Z.-Q. Gu ◽

P. Skolnick ◽

...

Keyword(s):

Molecular Modeling ◽

Receptor Agonist ◽

Benzodiazepine Receptor ◽

Biological Evaluation ◽

Computer Aided ◽

Benzodiazepine Receptor Agonist ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.04.015 ◽

2009 ◽

Vol 17 (16) ◽

pp. 6123-6136 ◽

Author(s):

Frank W. Foss ◽

Thomas P. Mathews ◽

Yugesh Kharel ◽

Perry C. Kennedy ◽

Ashley H. Snyder ◽

...

Keyword(s):

Sphingosine Kinase ◽

Biological Evaluation ◽

Sphingosine 1 Phosphate ◽

Kinase Substrates ◽

Synthesis And Biological Evaluation

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