Synthesis and biological evaluation of novel cyclopropyl derivatives as subtype-selective ligands for estrogen receptor

Zunyuan Wang; Yewei Yang; Xiaoliang Zheng; Tao Zhang; Wenhai Huang; Dongmei Yan; Wenjun Zhang; Xiaoju Wang; Zhengrong Shen

doi:10.1111/jphp.12908

Synthesis and biological evaluation of novel cyclopropyl derivatives as subtype-selective ligands for estrogen receptor

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.12908 ◽

2018 ◽

Vol 70 (7) ◽

pp. 910-918 ◽

Cited By ~ 2

Author(s):

Zunyuan Wang ◽

Yewei Yang ◽

Xiaoliang Zheng ◽

Tao Zhang ◽

Wenhai Huang ◽

...

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Selective Ligands ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Estrogen Receptor Subtype-Selective Ligands: Asymmetric Synthesis and Biological Evaluation ofcis- andtrans-5,11-Dialkyl- 5,6,11,12-tetrahydrochrysenes

Journal of Medicinal Chemistry ◽

10.1021/jm990101b ◽

1999 ◽

Vol 42 (13) ◽

pp. 2456-2468 ◽

Cited By ~ 103

Author(s):

Marvin J. Meyers ◽

Jun Sun ◽

Kathryn E. Carlson ◽

Benita S. Katzenellenbogen ◽

John A. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Asymmetric Synthesis ◽

Biological Evaluation ◽

Receptor Subtype ◽

Selective Ligands ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of cyclopropyl analogues of stilbene with raloxifene side chain as subtype-selective ligands for estrogen receptor

Archives of Pharmacal Research ◽

10.1007/s12272-013-0134-2 ◽

2013 ◽

Vol 36 (9) ◽

pp. 1096-1103 ◽

Cited By ~ 8

Author(s):

Hye Lim Yeo ◽

Yoon Sun Song ◽

Jae-Ha Ryu ◽

Hee-Doo Kim

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Side Chain ◽

Design Synthesis ◽

Selective Ligands ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Faculty Opinions recommendation of Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1064759.517678 ◽

2007 ◽

Author(s):

Hugh Rosen

Keyword(s):

Biological Evaluation ◽

Receptor Agonists ◽

Sphingosine 1 Phosphate ◽

Subtype Selective ◽

Synthesis And Biological Evaluation ◽

Receptor Agonists And Antagonists

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Synthesis and Biological Evaluation of 7,8,9,10-Tetrahydroimidazo[1,2-c]pyrido[3,4-e]pyrimdin-5(6H)-ones as Functionally Selective Ligands of the Benzodiazepine Receptor Site on the GABAAReceptor

Journal of Medicinal Chemistry ◽

10.1021/jm0202019 ◽

2002 ◽

Vol 45 (23) ◽

pp. 5043-5051 ◽

Cited By ~ 20

Author(s):

Pamela A. Albaugh ◽

Lu Marshall ◽

James Gregory ◽

Geoff White ◽

Alan Hutchison ◽

...

Keyword(s):

Receptor Site ◽

Benzodiazepine Receptor ◽

Biological Evaluation ◽

Selective Ligands ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor α and β agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.04.007 ◽

2010 ◽

Vol 18 (10) ◽

pp. 3437-3447 ◽

Cited By ~ 23

Author(s):

Pekka K. Poutiainen ◽

Tuomas A. Venäläinen ◽

Mikael Peräkylä ◽

Juha M. Matilainen ◽

Sami Väisänen ◽

...

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Α ◽

Biological Evaluation ◽

Hydroxy Ketones ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of novel m-carborane-containing estrogen receptor partial agonists as SERM candidates

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.05.083 ◽

2015 ◽

Vol 25 (16) ◽

pp. 3213-3216 ◽

Cited By ~ 8

Author(s):

Kiminori Ohta ◽

Takumi Ogawa ◽

Asako Kaise ◽

Yasuyuki Endo

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Partial Agonists ◽

Synthesis And Biological Evaluation

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Molecular design, chemical synthesis, and biological evaluation of agents that selectively photo-degrade the transcription factor estrogen receptor-α

Organic & Biomolecular Chemistry ◽

10.1039/c1ob05629h ◽

2011 ◽

Vol 9 (18) ◽

pp. 6357 ◽

Cited By ~ 9

Author(s):

Kana Tsumura ◽

Akane Suzuki ◽

Takeo Tsuzuki ◽

Shuho Tanimoto ◽

Hajime Kaneko ◽

...

Keyword(s):

Estrogen Receptor ◽

Transcription Factor ◽

Chemical Synthesis ◽

Molecular Design ◽

Estrogen Receptor Α ◽

Biological Evaluation ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of conformationally constrained sphingosine-1-phosphate analogs as subtype selective S1P receptor agonist/antagonist

10.18130/v3wg9m ◽

2008 ◽

Author(s):

Ran Zhu

Keyword(s):

Receptor Agonist ◽

Biological Evaluation ◽

Conformationally Constrained ◽

Sphingosine 1 Phosphate ◽

S1p Receptor ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel dual-acting modulators targeting both estrogen receptor α (ERα) and lysine-specific demethylase 1 (LSD1) for treatment of breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112281 ◽

2020 ◽

Vol 195 ◽

pp. 112281

Author(s):

Ming He ◽

Wentao Ning ◽

Zhiye Hu ◽

Jian Huang ◽

Chune Dong ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Estrogen Receptor Α ◽

Biological Evaluation ◽

Design Synthesis ◽

Lysine Specific Demethylase ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of a fluorine-18 labeled estrogen receptor-α selective ligand: [18F] propyl pyrazole triol

Nuclear Medicine and Biology ◽

10.1016/s0969-8051(02)00446-8 ◽

2003 ◽

Vol 30 (4) ◽

pp. 397-404 ◽

Cited By ~ 8

Author(s):

Dange Vijaykumar ◽

Mohammed H. Al-Qahtani ◽

Michael J. Welch ◽

John A. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Α ◽

Biological Evaluation ◽

Selective Ligand ◽

Synthesis And Biological Evaluation

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