A rare case of retroperitoneal castleman disease

Background. Hemophagocytic lymphohistiocytosis (HLH) is a rare condition associated with viral infections including HIV. Cases have been reported mainly in advanced HIV/AIDS. This is a rare case that reports HLH associated with human herpes virus-8 (HHV-8) associated multicentric Castleman disease in a stable HIV patient. Case Presentation. A 70-year-old Asian male patient with history of stable HIV on medications with CD 4 cell count above 200 presented with cough and fever and was initially treated for pneumonia as an outpatient. Persisting symptoms prompted presentation to the hospital. The patient was found to have anemia which persisted despite repeated transfusion of packed red cells. A bone marrow biopsy to investigate anemia revealed hemophagocytosis. A CT scan revealed multiple enlarged lymph nodes and hepatosplenomegaly. An excisional lymph node biopsy revealed HHV-8 associated multicentric Castleman disease. The patient deteriorated despite initiation of treatment. Conclusion. HLH can occur at any stage of HIV, rapid diagnosis to identify possible underlying reactive infectious etiology and prompt initiation of treatment is crucial to survival.

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A Rare Case of Bilateral Orbital Castleman Disease

Orbit ◽

10.3109/01676830.2014.904381 ◽

2014 ◽

Vol 33 (4) ◽

pp. 314-317

Author(s):

Bipasha Mukherjee ◽

Mohammad Shahid Alam ◽

S. Krishnakumar

Keyword(s):

Rare Case ◽

Castleman Disease

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A rare case of idiopathic multicentric Castleman disease in a patient with long-standing systemic autoimmunity

Scandinavian Journal of Rheumatology ◽

10.1080/03009742.2021.1947591 ◽

2021 ◽

pp. 1-3

Author(s):

M Saleh ◽

M Hallbeck ◽

C Sjöwall

Keyword(s):

Rare Case ◽

Castleman Disease ◽

Multicentric Castleman Disease ◽

Systemic Autoimmunity

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Doppler findings In castleman disease - A rare case

Indian Journal of Radiology and Imaging ◽

10.4103/0971-3026.29068 ◽

2006 ◽

Vol 16 (1) ◽

pp. 127 ◽

Cited By ~ 1

Author(s):

S Raniga ◽

C Shah ◽

A Shrivastava ◽

P Amin ◽

P Patel

Keyword(s):

Rare Case ◽

Castleman Disease

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A rare case of hyaline-type Castleman disease in the liver

World Journal of Hepatology ◽

10.4254/wjh.v5.i7.404 ◽

2013 ◽

Vol 5 (7) ◽

pp. 404 ◽

Cited By ~ 9

Author(s):

Hisaaki Miyoshi

Keyword(s):

Rare Case ◽

Castleman Disease

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Castleman Disease in the Buccal Space Mimicking Lymphoma: A Case Report

Advances in Bioscience and Clinical Medicine ◽

10.7575/aiac.abcmed.v.7n.3p.23 ◽

2019 ◽

Vol 7 (3) ◽

pp. 23

Author(s):

Mohsen Hashemi ◽

Javad Yazdani ◽

Amir Hossein Bani Shah Abadi ◽

Tannaz Abdollah Zade Baghai ◽

Behrouz Shokouhi

Keyword(s):

Case Report ◽

Lymphoproliferative Disorder ◽

Rare Case ◽

Systemic Treatment ◽

Surgical Excision ◽

Castleman Disease ◽

Unknown Etiology ◽

Histopathological Features ◽

Buccal Space

Castleman disease is a benign lymphoproliferative disorder of unknown etiology, more commonly appearing in the mediastinum. Craniofacial involvement is rare. Surgical excision is the only intervention needed for the unicentric type, while systemic treatment would be necessary for the multicentric type. Here, we report a rare case of unicentric castleman disease of the buccal space of a 23-year-old woman. Additionally, we review the radiological and histopathological features of this lesion.

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Suprarenal unicentric Castelman’s disease: A rare case report

Journal of Clinical Images and Medical Case Reports ◽

10.52768/2766-7820/1353 ◽

2021 ◽

Vol 2 (5) ◽

Author(s):

Mohammed Arafath Ali ◽

◽

Ramachandra C ◽

Uday Karjol ◽

Ravi Arjunan ◽

...

Keyword(s):

Ct Scan ◽

Complete Resolution ◽

Lymphoproliferative Disorder ◽

Rare Case ◽

Clinical Presentation ◽

Castleman Disease ◽

Malignant Diseases ◽

Rare Case Report ◽

Suprarenal Mass

Castleman Disease (CD) is a rare non-clonal lymphoproliferative disorder. The clinical presentation of CD often overlaps with autoimmune, infectious, or other malignant diseases. The diagnosis is confirmed by a biopsy of the affected lymph-node tissue. A 39-year-old gentleman was evaluated for intractable abdominal pain fatigue of 2 months duration. CT scan showed a 4 X 4 X 5 cm right suprarenal mass. Laparotomy and near total excision was performed which showed reactive B cells expressing CD20 and PAX5, favoring CD. Patient received adjuvant 6 cycles of Rituximab and steroids. A follow up CT scan after 3 months showed a near complete resolution.

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