scholarly journals Epidermal Growth Factor Improves the Ultrastructure of Submandibular Salivary Glands of Streptozotocin Induced Diabetic Rats - A Qualitative Study

2020 ◽  
Vol 9 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Mahmoud Al Ankily ◽  
Mohamed Shamel ◽  
Mahmoud M. Bakr ◽  
◽  
◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Qualitative Study ◽  
Salivary Glands ◽  
Diabetic Rats ◽  
Submandibular Salivary Glands ◽  
Epidermal Growth

scholarly journals Epidermal Growth Factor Secreted from Submandibular Salivary Glands Interferes with the Lipolytic Effect of Adrenaline in Mice*

Endocrinology ◽  
2000 ◽  
Vol 141 (3) ◽  
pp. 876-882 ◽  
Author(s):  
Francesc Tebar ◽  
Montserrat Grau ◽  
Maria-Pau Mena ◽  
Anna Arnau ◽  
Maria Soley ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Salivary Glands ◽  
Lipolytic Effect ◽  
Submandibular Salivary Glands ◽  
Epidermal Growth

Effect of sialoadenectomy on ethanol-induced gastric mucosal damage in the rat: role of neutrophils

1990 ◽  
Vol 68 (2) ◽  
pp. 207-210 ◽  
Author(s):  
B. L. Tepperman ◽  
B. D. Soper
Keyword(s):  
Growth Factor ◽  
Gastric Mucosa ◽  
Epidermal Growth Factor ◽  
Salivary Glands ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Mucosal Inflammation ◽  
Prostaglandin E ◽  
Epidermal Growth ◽  
Extent Of Damage

We have observed that removal of the salivary glands is associated with an increase in the susceptibility to gastric mucosal damage in the rat. In the present study, we have examined the effect of sialoadenectomy on ethanol-induced mucosal hemorrhagic damage and myeloperoxidase (MPO) activity. Hemorrhagic damage and MPO activity in response to intragastric 50% w/v ethanol were greater in sialoadenectomized rats when compared with sham-operated animals. Pretreatment with 16,16-dimethylprostaglandin E2 (0.3 μg/kg s.c.) reduced damage and MPO activity in both sialoadenectomized and sham control rats receiving 50% ethanol. The reduction in these parameters was greater in control than in sialoadenectomized rats. Pretreatment with epidermal growth factor (5 μg/kg s.c.) significantly reduced MPO activity but did not significantly affect the extent of damage. These data suggest that sialoadenectomy is associated with an increase in mucosal inflammation in animals given ethanol. However, in some situations tissue inflammation (as indicated by MPO activity) was reduced, while the proportion of gastric mucosa exhibiting hemorrhagic damage was not changed.Key words: salivary glands, gastric mucosa, neutrophils, prostaglandin E2, epidermal growth factor.

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