The Effect of Top G2 Liquid Organic Fertilizer and SP-36 Fertilizer on Peanut Plant Growth and Yield

The purpose of this study is to find out the effect of the administration of Top G2 liquid organic fertilizer and SP-36 fertilizer on peanut crop yields, to know the dose of SP-36 fertilizer and Top G2 liquid organic fertilizer that can produce the best peanut crop results and to know the interaction of liquid organic fertilizer Top G2 and SP-36 fertilizer in improving the yield of peanut crops. The design used in this study is a Randomized Group Design (RGD) factorial pattern. This treatment consists of two factors: First Factor: Concentration of POC Top G2 consisting of OC0: No POC Top G2, OC1: POC Top G2 4 cc ltr air-1petak-1 OC2: POC Top G2 8 cc ltr water-1Swath-1; The second factor: Fertilizer Dose P (SP36) consists of P0: Without SP36 fertilizer; P1: 300 kg ha-1; Q2: 400 kg ha-1. The results showed that the administration of g2 top liquid organic fertilizer with a concentration of 8 cc ltr water-1 produced the highest plant height of 20.75 cm tan-1, the number of leaves 27.36 strands of tan-1, the number of pods 39.89 tan-1 and the harvest index 0.326. The interaction of g2 top liquid organic fertilizer and phosphorus fertilizer increases the weight of dried seeds harvesting crops, i.e. in the treatment of liquid fertilizer concentration top G2 8 cc ltr water-1 plot-1 with a seed weight of 235 g tan-1. Cultivation of peanut crops should use liquid organic fertilizer top G2 concentration eight cc tr water-1 tile-1 and need further research using higher concentrations of liquid organic fertilizer top G2 to see the optimum needs of peanut crops.

Intraocular epidermal growth factor concentration, axial length, and high axial myopia

Purpose Various molecules such as dopamine have been found to be associated with axial elongation in experimental studies. Here, we examined whether intraocular EGF is associated with axial length in myopic patients. Methods The hospital-based investigation included patients of European descent without optic nerve, retinal, or macular diseases except for myopic maculopathy. Using aqueous humor samples collected during surgery, the EGF concentration was examined applying a cytometric bead array. High myopia was defined by an axial length of ≥ 27.0 mm. Results The study included a non-highly myopic group of 11 patients (mean age, 72.9 ± 10.8 years; mean axial length, 24.3 ± 1.1 mm) and a highly myopic group of three patients (age, 81.11 ± 12.3 years; axial length, 29.5 ± 1.3 mm), with one of them having pathologic myopic maculopathy. In multivariable linear regression analysis, higher EGF concentration was correlated with the highly myopic versus non-highly myopic group (beta, 1.24; non-standardized correlation coefficient B, 6.24; 95% confidence interval (CI), 0.10,12.4;P = 0.047) after adjusting for axial length. The amount of intraocular EGF was significantly higher in the highly myopic group than in the non-highly myopic group (89.1 ± 40.8 pg versus 34.1 ± 13.2 pg; P = 0.005), and it was highest in the eye with myopic maculopathy (135 pg). Conclusions The intraocular amount of EGF is higher in highly myopic versus non-highly myopic eyes.

Effect of Hypoxia Preconditioned Secretomes on Lymphangiogenic and Angiogenic Sprouting: An in Vitro Analysis

Hypoxia Preconditioned Plasma (HPP) and Serum (HPS) are two blood-derived autologous growth factor compositions that are being clinically employed as tools for promoting tissue regeneration, and have been extensively examined for their angiogenic activity. As yet, their ability to stimulate/support lymphangiogenesis remains unknown, although this is an important but often-neglected process in wound healing and tissue repair. Here we set out to characterize the potential of hypoxia preconditioned secretomes as promoters of angiogenic and lymphangiogenic sprouting in vitro. We first analysed HPP/HPS in terms of pro- (VEGF-C) and anti- (TSP-1, PF-4) angiogenic/lymphangiogenic growth factor concentration, before testing their ability to stimulate microvessel sprouting in the mouse aortic ring assay and lymphatic sprouting in the thoracic duct ring assay. The origin of lymphatic structures was validated with lymph-specific immunohistochemical staining (Anti-LYVE-1) and lymphatic vessel-associated protein (polydom) quantification in culture supernatants. HPP/HPS induced greater angiogenic and lymphatic sprouting compared to non-hypoxia preconditioned samples (normal plasma/serum), a response that was compatible with their higher VEGF-C concentration. These findings demonstrate that hypoxia preconditioned blood-derived secretomes have the ability to not only support sprouting angiogenesis, but also lymphangiogenesis, which underlines their multimodal regenerative potential.